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22 Nov 2019 | 10:20 PM (IST)
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Mevotrex 10 Tablet


Overview

Introduction

Mevotrex 10 Tablet is a medicine used to treat rheumatoid arthritis where it can prevent further joint damage. It is also used to treat severe forms of a skin disease called psoriasis by killing cells in the skin which are growing too quickly.

Mevotrex 10 Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking it too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, abdominal pain, tiredness, and mouth sores. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is a very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you are pregnant, have stomach, liver or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, x-rays and physical examinations both before and during treatment with this medicine.

Uses of Mevotrex Tablet

Side effects of Mevotrex Tablet

Common
  • Abdominal pain
  • Dyspepsia
  • Loss of appetite
  • Nausea
  • Vomiting
  • Tiredness
  • Mouth sore

How to use Mevotrex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mevotrex 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Mevotrex Tablet works

Mevotrex 10 Tablet is an immunosuppressant. In rheumatoid arthritis, it works by decreasing the activity of body's immune system. This decreases swelling, reduces pain and stiffness, and improves function. In psoriasis, it works by slowing down the rapid growth of skin cells.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Mevotrex 10 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Mevotrex 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
UNSAFE
Mevotrex 10 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Mevotrex 10 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Mevotrex 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mevotrex 10 Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Mevotrex 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Mevotrex 10 Tablet may be needed. Please consult your doctor.
Use of Mevotrex 10 Tablet is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Mevotrex 10 Tablet
₹12.77/Tablet
Folitrax 10 Tablet
Ipca Laboratories Ltd
₹12.48/Tablet
save 2%
Mexate 10 Tablet
Zydus Cadila
₹12.48/Tablet
save 2%
Mext 10 Tablet
Wallace Pharmaceuticals Pvt Ltd
₹12.48/Tablet
save 2%
₹11.97/Tablet
save 6%
Dermotrex 10mg Tablet
East West Pharma
₹13.89/Tablet
9% costlier

Quick Tips

  • Take it once a week, on the same day every week.
  • Drink plenty of liquids to stay hydrated while taking this  medication.
  • Always take folic acid as advised by your doctor. This will help lessen the side effects of this medicine.
  • It may take 6 to 8 weeks for Mevotrex 10 Tablet to work. Keep taking the medication as prescribed.
  • Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
  • It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.

Interaction with Drugs

Taking Mevotrex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Rotasiil, Rotarix, RotaTeq
LIFE-THREATENING
LIFE-THREATENING
Brand(s): Abhay M, Measles, M-Vac
LIFE-THREATENING
Brand(s): Rubella
LIFE-THREATENING

Patient Concerns

arrow
Rheumatoid arthritis with severe deformities from last 10 years
Dr. Akshat Goel
Bone & Joint Specialist
Please refer to a Rheumatologist In-person for detailed examination of deformed joints
Rheumatoid arthritis diseases attackRheumatoid arthritis diseases tablet for this
Dr. Vipul Aggarwal
Bone & Joint Specialist
please consult rheumatologist for the same
arrow
Do you have any questions related to Mevotrex 10 Tablet ?

User Feedback


FAQs

Q. Can Mevotrex cause mouth ulcers?

Yes, in fact a sore mouth and mouth ulcers are sometimes side effects of Mevotrex therapy. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Q. Why do I have to take folic acid with Mevotrex?

Folic acid is required to make new cells in the body and Mevotrex decreases the folic acid levels in the body. By taking folic acid some of the common side effects, like mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems can be reduced.

Q. Why do I need to take regular blood tests while taking Mevotrex?

Regular blood tests will help your doctor to check your response to Mevotrex and monitor you for side effects. You will need to regularly check your liver function and your blood counts -white blood cells, red blood cells and platelets. Your doctor may also order additional tests depending on the results.

Q. Can Mevotrex use make me more prone to infections?

Mevotrex may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports of serious lung infections with Mevotrex use. If you have an active infection, Mevotrex should be used with extreme caution.

Q. Can Mevotrex affect fertility?

Yes, it may affect fertility in both males and females. There may be a decrease in sperm count in males and menstrual disturbances in females. These effects are reversible and disappear once the therapy is discontinued.

Q. What to do if I am planning to become pregnant and my husband is taking Mevotrex?

You should avoid pregnancy if your husband is taking Mevotrex. Also, avoid pregnancy for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
  3. Methotrexate. Camberley, Surrey: Sandoz Limited; 2005 [revised 23 Mar. 2018]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  4. Drugs.com. Methotrexate Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Methotrexate. Feucht, Germany: EXCELLA GmbH; 2016. [Accessed 26 Mar. 2019] (online) Available from:External Link
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