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Metacin Tablet

Paracetamol (500mg)
Genuine
Authenticity Assured
NPPA Regulated
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Metacin Tablet helps relieve pain and fever by blocking the release of certain chemical messengers responsible for fever and pain. It is used to treat headaches, migraine, toothaches, sore throats, period (menstrual) pains, arthritis, muscle aches, and the common cold.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 01 Apr 2026 | 01:02 PM (IST)
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Product introduction

Metacin Tablet may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended.

Side effects are rare if this medicine is used correctly but this medicine may cause stomach pain, nausea, and vomiting in some people. Consult your doctor if any of these side effects bother you or do not go away.

This medicine is widely prescribed and considered safe but is not suitable for everybody. Before taking it, let your doctor know if you have liver or kidney problems or are using blood-thinning medicines. It may affect the dose or suitability of this medicine. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Uses of Metacin Tablet

Benefits of Metacin Tablet

Pain relief
Metacin Tablet is a common painkiller for treating aches and pains. It is widely used and rarely causes any side effects if taken properly. To get the most benefits, take it as prescribed. Do not take more or for longer than needed as that can be dangerous.
Treatment of Fever
Metacin Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with other medicines. Take it as prescribed by the doctor.

Side effects of Metacin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metacin
  • Nausea
  • Vomiting
  • Constipation
  • Itching
  • Headache
  • Insomnia (difficulty in sleeping)

How to use Metacin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metacin Tablet should be taken with or after food.

How Metacin Tablet works

Metacin Tablet is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

Quick tips

  • Metacin Tablet should be taken with food or milk to prevent an upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
  • Do not take indigestion remedies (antacids) within two hours of taking Metacin Tablet.
  • Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
  • Inform your doctor if you have liver disease as your dose may need to be adjusted.
  • The doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking Metacin Tablet for long-term treatment.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Metacin Tablet.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Metacin Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

SAFE
Metacin Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Metacin Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, Metacin Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.
Liver

Liver

UNSAFE
Metacin Tablet is unsafe to use in patients with liver disease and should be avoided.
However, the use of Metacin Tablet is not recommended in patients with severe liver disease and active liver disease.

Interaction with drugs

Taking Metacin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Bemiparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Certoparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Cholestyramine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Paracetamol may increase the effect of Cholestyramine.
Moderate

Dalteparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Enoxaparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.

Frequently asked questions

If you vomit in less than 30 minutes after having a dose of Metacin Tablet tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Usually, you will start feeling better after about half an hour of taking a Metacin Tablet.
You should only take four doses of Metacin Tablet in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Metacin Tablet for more than 3 days without consulting a doctor first.
No, Metacin Tablet is not an antibiotic. It works as a painkiller and fever-reducing medicine.
Ibuprofen and Metacin Tablet are safe medicines, but both should not be used together. Consult your doctor if you are not sure.
Metacin Tablet takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.
Overdose of Metacin Tablete may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.
Yes, Metacin Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.<br>
No, Metacin Tablet should not be taken for stomach pain without consulting a doctor. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Yes, taking Metacin Tablet and antibiotics at the same time should not cause any problems. Antibiotics are used to help clear infections but often don't do anything to relieve pain. Therefore you can generally take Metacin Tablet alongside your antibiotics. However, always consult your doctor before taking any medications.
If you vomit in less than 30 minutes after having a dose of Metacin Tablet tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Usually, you will start feeling better after about half an hour of taking a Metacin Tablet.
You should only take four doses of Metacin Tablet in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Metacin Tablet for more than 3 days without consulting a doctor first.
No, Metacin Tablet does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
Metacin Tablet is considered safe for children only when used as directed by the doctor.
If you take Metacin Tablet tablet when you don’t have a fever, then any minor pain or ache you might be experiencing in your body will be relieved. If you don’t have any pain, you will not notice any difference. At low doses, Metacin Tablet is harmless.

Fact Box

Chemical Class

1- hydroxy- 2- unsubstituted benzenoids

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Analgesic & Antipyretic-PCM

Related lab tests

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 635-36.
  2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 8-12.
  4. Paracetamol. County Tipperary, Ireland: Pinewood Healthcare; 2015. [Accessed 17 Jun. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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User feedback

Once A Day
58%
Twice A Day
19%
Thrice A Day
14%
Four Times A Day
8%
Alternate Day
2%
Fever
51%
Headache
18%
Pain relief
18%
Others
11%
Pain during menstruation
3%
Excellent
40%
Average
34%
Poor
26%
No Side Effect
47%
Allergic reaction
20%
Liver damage
20%
Vomiting
7%
Stomach pain
7%
With food
76%
With or without food
20%
Empty stomach
4%
Not Expensive
64%
Average
25%
Expensive
12%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)THEMIS PHARMACEUTICALS
Address: A)69-B, G.I.D.C. Industrial Estate, Vapi-396 195

Marketer details

Name: Themis Pharmaceuticals Prop Chemosyn Ltd
Address: 69-B , J-type area ,G.I.D.C. Industrial Estate,Near CNG Gas Station,Vapi- 396195

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Metacin Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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