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Memo-G Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 11 Feb 2026 | 01:32 PM (IST)
Memo-G Tablet is a medicine used in the treatment of Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's disease by improving memory and thinking. This medicine works by blocking a chemical messenger involved in the transmission of nerve signals.
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General Information

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Product introduction

Memo-G Tablet maybe taken with or without food. However, it is advised to take it at the same time each day to maintain a consistent level of medicine in the blood. If you missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor.


The most common side effects of this medicine are dizziness, headache, drowsiness, and constipation. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.


Before taking this medicine, inform the doctor if you have a history of seizures, kidney disease, heart disease, or liver disease. Let your doctor also know if you are taking any other medicines for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.

Uses of Memo-G Tablet

Benefits of Memo-G Tablet

Alzheimer's disease
Memo-G Tablet helps manage symptoms of Alzheimer’s disease by improving memory, attention, and the ability to perform daily activities. It may slow the progression of cognitive decline, helping patients maintain independence for a longer time.

Side effects of Memo-G Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Memo-G
  • Dizziness
  • Constipation
  • Headache
  • High blood pressure
  • Breathing problems
  • Drowsiness

How to use Memo-G Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Memo-G Tablet may be taken with or without food.

How Memo-G Tablet works

Memo-G Tablet is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Memo-G Tablet works by preventing the action of NMDA receptors and regulates the production of glutamate.  involved in the transmission of nerve signals. This is how it prevents memory loss in Alzheimer’s disease.

Quick tips

  • You have been prescribed Memo-G Tablet to treat dementia (memory loss) in patients with Alzheimer's disease.
  • It is well tolerated and has lesser side effects as compared to other similar medicines.
  • Be cautious while driving or doing anything that requires concentration until you know how Memo-G Tablet affects you.
  • Inform your doctor if you have a history of seizures, kidney disease, heart disease, or liver disease.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Memo-G Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Memo-G Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Memo-G Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Memo-G Tablet may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Memo-G Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Memo-G Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.
In severe liver impairment, it should not be given.

Interaction with drugs

Taking Memo-G with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Amantadine (Oral Route)

Do not consume Memantine with Amantadine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Amisulpride (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Memantine may reduce efficacy of Amisulpride.
Moderate

Amisulpride (Injection Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Memantine may reduce efficacy of Amisulpride.
Moderate

Aripiprazole (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Memantine may reduce efficacy of Aripiprazole.
Moderate

Chlorpromazine (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Memantine may reduce efficacy of Chlorpromazine.

Frequently asked questions

No, Memo-G Tablet does not have abuse potential. On the contrary, it may prevent excess use of addictive drugs such as morphine or ethanol.
Memo-G Tablet should be taken orally once a day. To benefit from your medicine you should take it regularly every day at the same time of the day. The tablets should be swallowed with some water. The tablets can be taken with or without food.
For Memo-G Tablet to start working and show its full benefits, it may require between 3 and 8 hours. The doctor may require a follow-up clinical assessment to check the progress after 4 weeks and then 6 months after the first assessment.
The symptoms which can be observed due to an overdose of Memo-G Tablet include tiredness, weakness, drowsiness, confusion, hallucinations, and/or vomiting. Some may also experience diarrhea, vertigo, agitation, aggression, and walking difficulty.
Memo-G Tablet belongs to a class of medications called N-methyl-D- aspartate (NMDA) receptor antagonists. It works by decreasing abnormal activity in the brain. Memo-G Tablet may improve the ability to think and remember. It may also reduce the deterioration of these abilities in people who have Alzheimer's disease. However, with time the effectiveness of this medicine will reduce and it may not be able to cure Alzheimer's disease or prevent the loss of these abilities.
Dementia is a syndrome in which there is deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Dementia is one of the major causes of disability and dependency among older people worldwide. Alzheimer disease is the most common form of dementia which contributes to around 60 to 70% of cases.
No, Memo-G Tablet should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimer's disease but does not cure it. If you need to stop the medication then doctor should be consulted first.
Yes, Memo-G Tablet may make you sleepy. Memo-G Tablet has minor to moderate influence on the ability to drive and usage of machines. In such cases, outpatients should be warned to take special care.
Yes, Memo-G Tablet can be combined with donepezil, as there will be no increased adverse effects. However, this combination will not cure Alzheimer's, but it can only improve thinking ability, short term memory, and other related symptoms.
Memo-G Tablet can interact with several medicines. Taking other medicines along with Memo-G Tablet can either make Memo-G Tablet less effective or increase its side effect. Do not take any medicine without talking to your doctor.
Yes, Memo-G Tablet may interfere with the working of hydrochlorothiazide (HCT). It decreases the levels of HCT which will reduce the effectiveness of HCT. Also, procainamide and quinidine may increase levels of Memo-G Tablet which may cause increased toxicity.
No, keep using Memo-G Tablet as advised by your doctor, even if you feel well. Stopping Memo-G Tablet can bring back your symptoms of dementia.

Fact Box

Chemical Class

Monoalkylamines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

NMDA (N-methyl-D-aspartate) Receptor Antagonists

References

  1. Katzung BG. Special Aspect of Geriatric Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1141-42.
  2. Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 622.
  3. Stahl SM, editor. Memantine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 397-400.
  4. Memantine HCl. Dublin, Ireland: Forest Laboratories Ireland Ltd.; 2003 [revised Oct 2013]. [Accessed 25 Jan. 2019] (online) Available from:
  5. Memantine hydrochloride [EMC SmPC]. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2013 [revised Jun. 2015]. [Accessed 25 Mar 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
  7. Central Drugs Standard Control Organisation. Memantine. [Accessed 11 Jul. 2023]. (online) Available from:
  8. Memantine Hydrochloride [Patient Information Leaflet]. Bachupally, India: Dr. Reddy’s Laboratories Limited. [Accessed 11 Jul. 2023]. (online) Available from:
  9. Memantine hydrochloride [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited (Formulation Division); 2023. [Accessed 11 Jul. 2023]. (online) Available from:
  10. Memantine hydrochloride [Prescribing Information]. Schimatari, Greece: Accord Healthcare Single Member S.A.; [Accessed 11 Feb. 2026]. (online). Available from:
  11. Memantine hydrochloride. Tipperary, Ireland 2021 [Accessed 11 Feb. 2026]. (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Address: Tuttsan House Survey No.92, Plot No.14,Marigold compound Nr. CRI pump,Khatraj Chowkdi, Taluka Kalol, Dist: Gandhinagar- 382721, Gujarat, India

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Country of origin: India
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