Manitonika Injection

Mannitol (20% w/v)

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Manitonika Injection is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to reduce the pressure inside the eyes in a condition called glaucoma.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 29 May 2026 | 12:02 PM (IST)

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General Information

Contains

Mannitol (20% w/v)

Marketer

Tara Biosciences Private Limited

Storage

Store below 25°C

The content is shown in English

Product introduction

Manitonika Injection works by removing excess water and also relieves inflammation in the affected areas. It may be used alone or in combination with other medicines. It is administered as an injection under the supervision of a medical professional and should not be self administered. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember.

Some common side effects of this medicine include nausea, vomiting, headache, and dehydration. You may also notice some injection site reactions such as pain, redness or swelling. However, these are temporary and usually subside on their own after some time. Please consult your doctor if these do not subside or bother you. Regular monitoring by blood tests may be required while using this medicine.

Uses of Manitonika Infusion

Glaucoma
Acute renal failure
Cerebral edema (accumulation of excessive fluid in the brain)

Benefits of Manitonika Infusion

Glaucoma
Manitonika Injection is used in glaucoma to rapidly lower eye pressure, providing relief from pain and helping prevent vision loss during acute episodes.

Acute renal failure
In acute renal failure, Manitonika Injection supports urine production and helps flush out toxins, aiding in kidney function recovery.

Cerebral edema (accumulation of excessive fluid in the brain)
Manitonika Injection helps reduce swelling in the brain by drawing excess fluid away, relieving pressure and lowering the risk of complications from brain injuries or conditions.

Side effects of Manitonika Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Manitonika

Nausea
Vomiting
Headache
Dehydration
Injection site reactions (pain, swelling, redness)

How to use Manitonika Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Manitonika Infusion works

Manitonika Injection is an inert substance with high osmotic pressure. It draws water into the kidney, which in turn increases the amount of urine production. Manitonika Injection is also used to lower the pressure inside the eye or swelling around the brain.

All substitutes for Manitonika Injection

For information purposes only. Consult a doctor before taking any medicine.

Fabitol 20% Infusion

by Elkos Healthcare Pvt Ltd

₹0.25/ml of infusion

26% cheaper

Quick tips

It is given as an injection into the veins by a doctor or healthcare professional.
Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
It is given as an injection into the veins by a doctor or healthcare professional.
Your doctor may get regular blood tests done to monitor sodium and potassium level, kidney function, and lung function while you are taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Manitonika Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Manitonika Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Manitonika Injection during breastfeeding is not available. Please consult your doctor.

Driving

NOT RELEVANT

Not relevant, as Manitonika Injection is intended for use in hospitalized patients.

Kidney

CAUTION

Manitonika Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Manitonika Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Manitonika with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tobramycin (Injection Route)

Do not consume Tobramycin with Mannitol. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Tobramycin (Inhalation Route)

Do not consume Tobramycin with Mannitol. If concurrent use is essential, your doctor may monitor your kidney function closely.

Severe

Tobramycin (Oral Route)

Do not consume Tobramycin with Mannitol. If concurrent use is essential, your doctor may monitor your kidney function closely.

Moderate

Lamivudine (Oral Route)

Do not consume Lamivudine with Mannitol. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Mannitol may reduce blood levels of Lamivudine.

Moderate

Atracurium (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required. Mannitol may increase the effect of Atracurium.

Frequently asked questions

What is Manitonika Injection used for?

Manitonika Injection is used to help remove extra fluid from your body. It is often given in hospitals to reduce pressure in the brain (after injury or surgery) or in the eyes (like in glaucoma). It can also help your kidneys produce urine when they are not working well and help flush out certain poisons from the body.

Who should not receive Manitonika Injection?

Individuals should not receive Manitonika Injection if they have severe kidney problems, heart failure, lung congestion, severe dehydration, or active bleeding inside the brain (except during surgery). It should also be avoided if the individual is allergic to mannitol.

Is Manitonika Injection safe for people with kidney problems?

Manitonika Injection should be used with great care if your kidneys are not working well. Your doctor may give a small test dose first to check if your kidneys can handle it. If you stop passing urine or your kidney function worsens, the treatment is usually stopped immediately.

Can Manitonika Injection cause brain swelling or confusion?

In some people, Manitonika Injection can cross into the brain and cause confusion, drowsiness, or even worsen swelling in certain cases, especially if the protective barrier between the brain and blood is damaged. Your doctor will monitor you closely to avoid this.

What serious side effects of Manitonika Injection should I watch for?

Serious side effects of Manitonika Injection may include difficulty breathing, chest pain, confusion, reduced urination, or swelling in your feet. These can be signs of fluid overload, heart failure, or kidney problems, which require medical attention.

Why is Manitonika Injection used to lower pressure in the brain and eyes?

Manitonika Injection helps draw excess fluid out of tissues into the bloodstream, reducing swelling and pressure in the brain and eyes. It is commonly used in emergencies like head injury, stroke, or glaucoma when other treatments are not enough.

Can Manitonika Injection affect my body’s water and salt balance?

Yes, Manitonika Injection can change your body’s water and electrolyte levels, sometimes leading to dehydration, high or low sodium, or acid‑base imbalance. Doctors check your blood and urine regularly to keep this in control.

What happens if Manitonika Injection builds up in the body?

If Manitonika Injection is not removed properly by the kidneys, it can build up, causing too much fluid in the body, swelling, or even worsening heart or kidney problems. That is why it is given under close hospital supervision.

Can Manitonika Injection affect people with heart problems?

Yes, Manitonika Injection can cause too much fluid in the bloodstream, which may worsen heart failure or cause lung congestion. Doctors will check your heart condition carefully before giving it.

Why do doctors monitor urine output closely during Manitonika Injection?

Urine output helps doctors know if your kidneys are removing Manitonika Injection effectively. Low or no urine during treatment may mean your kidneys are not tolerating it, and the infusion might need to be stopped.

Is Manitonika Injection safe for older adults or children?

Older adults and children may be more sensitive to fluid or electrolyte imbalances caused by Manitonika Injection. The dose is adjusted carefully based on age, weight, and medical condition.

Fact Box

Chemical Class

Sugar alcohols

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Osmotic Diuretics

Related lab tests

Blood Urea Nitrogen

Creatinine - Spot

Kidney Function Test

Sodium

Urine Routine & Microscopy

References

Ives HE. Diuretic Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 263.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 836-37.
Mannitol. Thetford, Norfolk: Baxter Healthcare Ltd.; 2003 [revised Jan. 2017]. [Accessed 25 Mar 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Tara Biosciences Private Limited
Address: E-41 H RIICO IA khushkheda 301707, Bhiwadi,Rajasthan

Vendor Details

Country of origin: India

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Manitonika Injection

Manitonika Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Manitonika Infusion

Benefits of Manitonika Infusion

Side effects of Manitonika Infusion

How to use Manitonika Infusion

How Manitonika Infusion works

All substitutes for Manitonika Injection

Fabitol 20% Infusion

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tobramycin (Injection Route)

Tobramycin (Inhalation Route)

Tobramycin (Oral Route)

Lamivudine (Oral Route)

Atracurium (Injection Route)

Frequently asked questions

What is Manitonika Injection used for?

Who should not receive Manitonika Injection?

Is Manitonika Injection safe for people with kidney problems?

Can Manitonika Injection cause brain swelling or confusion?

What serious side effects of Manitonika Injection should I watch for?

Why is Manitonika Injection used to lower pressure in the brain and eyes?

Can Manitonika Injection affect my body’s water and salt balance?

What happens if Manitonika Injection builds up in the body?

Can Manitonika Injection affect people with heart problems?

Why do doctors monitor urine output closely during Manitonika Injection?

Is Manitonika Injection safe for older adults or children?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Blood Urea Nitrogen

Creatinine - Spot

Kidney Function Test

Sodium

Urine Routine & Microscopy

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests