Makclop 5mg Injection

Metoclopramide (5mg)

Genuine

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Makclop 5mg Injection is a prescription medicine used to treat nausea, vomiting, indigestion, and heartburn. It prevents the feeling of fullness during or shortly after a meal and help reduce symptoms caused by the flow of the stomach contents back into the food pipe.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Apr 2026 | 04:20 PM (IST)

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General Information

Contains

Metoclopramide (5mg)

Marketer

Makcur Laboratories Ltd.

Storage

Store below 30°C

The content is shown in English

Product introduction

Makclop 5mg Injection is given by your doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. You should take this medicine until your doctor tells you to stop. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are restlessness, fatigue, and weakness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It also causes drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. This medicine may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration.

Before taking this medicine, you should let your doctor know if you have liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor.

Uses of Makclop Injection

Benefits of Makclop Injection

Treatment of Indigestion
Indigestion means discomfort of mainly the upper part of your stomach which may also have other symptoms such as stomach pain, bloating, feeling full etc. Makclop 5mg Injection improves the movement of food in your stomach and gut (intestine). This relieves these symptoms and helps in proper digestion of food.

Take Makclop 5mg Injection as prescribed by the doctor. Think about what foods trigger indigestion and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Side effects of Makclop Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Makclop

Weakness
Restlessness
Fatigue

How to use Makclop Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Makclop Injection works

Makclop 5mg Injection is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

All substitutes for Makclop 5mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Makclop 5mg Injection helps relieve nausea, vomiting, indigestion and heartburn.
It is usually given as an injection into a vein or muscle by your doctor.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Makclop 5mg Injection as it may cause excessive drowsiness.
Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Makclop 5mg Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy

SAFE IF PRESCRIBED

Makclop 5mg Injection is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Makclop 5mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Makclop 5mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Makclop 5mg Injection may cause drowsiness, dizziness, dyskinesia and dystonias which could affect the vision and may interfere with the ability to drive.

Kidney

CAUTION

Makclop 5mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Makclop 5mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Makclop with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Thioridazine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Paroxetine (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.

Moderate

Venlafaxine (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.

Moderate

Vilazodone (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.

Moderate

Sertraline (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.

Frequently asked questions

Does Makclop 5mg Injection work for morning sickness?

Makclop 5mg Injection can help in relieving morning sickness. However, this is not an approved indication for its use. There are other medicines also available to treat morning sickness. Consult a doctor if you need treatment for morning sickness as you should not take any medicine during pregnancy without consulting a doctor.

Can I take Makclop 5mg Injection with ranitidine?

Makclop 5mg Injection can be taken with ranitidine. No drug-drug interactions have been reported between the two. However, interactions can occur. Talk to your doctor before taking the two medicines together.

Fact Box

Chemical Class

Aminophenyl ethers

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Dopamine D2 Receptor Antagonists- Prokinetic Agents

References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1325-26.
McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Trevor AJ, editors. Basic & Clinical Pharmacology. 13th ed. New York, New York: McGraw-Hill Education; 2015. [Accessed 29 Jan. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 28 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Makcur Laboratories Ltd.
Address: CORPORATE OFFICE: No. 9/1, Magnet Corporate Park,Nr. Sola Bridge, Off. S.G.Highway, Ahmedabad – 380054 Gujarat.INDIA

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Makclop 5mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Makclop Injection

Benefits of Makclop Injection

Side effects of Makclop Injection

How to use Makclop Injection

How Makclop Injection works

All substitutes for Makclop 5mg Injection

Reglan 5mg Injection

Peridon 5mg Injection

Vominorm 5mg Injection

Clomet 5mg Injection

Esmet 5mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Thioridazine (Oral Route)

Paroxetine (Oral Route)

Venlafaxine (Oral Route)

Vilazodone (Oral Route)

Sertraline (Oral Route)

Frequently asked questions

Does Makclop 5mg Injection work for morning sickness?

Can I take Makclop 5mg Injection with ranitidine?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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