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Macquin 500mg Tablet 1
Macquin 500mg Tablet 2
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Macquin 500mg Tablet

Quinidine (500mg)
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Product Summary :

Macquin 500mg Tablet is an antiarrhythmic medicine used for selected abnormal heart rhythms. It slows electrical signal conduction in the heart and prolongs the recovery period between heartbeats. Take it only as prescribed and attend regular ECG and blood-test monitoring, as it can cause serious heart rhythm disturbances.


Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 04 Nov 2026 | 05:07 PM (IST)
₹214 MRP ₹233.038% off 
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General Information

The content is shown in English
Macquin 500mg Tablet 1
Macquin 500mg Tablet 2

Product introduction

Macquin 500mg Tablet is a medicine used to treat arrhythmia (abnormal heart rhythm). It restores normal heart rhythm by blocking abnormal electrical signals in the heart. This helps to maintain a regular and steady heartbeat.

Macquin 500mg Tablet should be taken exactly as prescribed by your doctor. The dose and timing depend on the type of heart rhythm problem and the formulation prescribed. Follow the instructions on your medicine pack regarding food, and do not change the dose or stop taking it without consulting your doctor.


It may cause nausea, vomiting, diarrhoea, dizziness, headache, ringing in the ears and changes in vision. It can also affect the heart's electrical activity and may cause serious irregular heartbeats. Seek immediate medical attention if you experience fainting, severe dizziness, chest pain, breathlessness or a new or worsening irregular heartbeat.


Your doctor may monitor your heart rhythm using an ECG and check your blood pressure and blood levels of potassium and magnesium. Inform your doctor about all medicines and supplements you take, especially medicines that affect heart rhythm. Tell your doctor if you have heart, liver or kidney problems, or if you are pregnant, planning a pregnancy or breastfeeding.

Uses of Macquin Tablet

Benefits of Macquin Tablet

Arrhythmia
Arrhythmia is a condition where the heart beats irregularly, too quickly, or too slowly, affecting its ability to pump blood efficiently. Macquin 500mg Tablet helps restore and maintain a normal heart rhythm, improving blood flow and reducing symptoms such as palpitations, fatigue, or dizziness. This supports healthy heart function and helps prevent complications related to abnormal heart rhythms.

Side effects of Macquin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Macquin
  • Diarrhea
  • Vomiting
  • Dizziness
  • Weakness
  • Abdominal discomfort
  • Hypotension (low blood pressure)
  • Hearing impairment
  • Skin rash

How to use Macquin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macquin 500mg Tablet should be taken with or after food.

How Macquin Tablet works

Macquin 500mg Tablet is an anti-arrhythmic medication. It works by blocking abnormal electrical signals in the heart to correct irregular heartbeat to a normal rhythm.

Dosage

The dose depends on the type of arrhythmia you are being treated for. Take it only in the dose and at the intervals prescribed by your doctor. Do not change the brand name in between your treatment.

Quick tips

  • It may cause dizziness. Do not drive or perform activities require mental focus until you know how it affects you.
  • Do not start any medicine including prescription or over-the-counter medicines without informing your doctor, as they may alter Macquin 500mg Tablet levels in your body.
  • Your doctor may get blood tests done to check your sodium and potassium levels, kidney function, and lung function before starting treatment with this medicine.
  • Your doctor may regularly monitor blood sugar level while taking this medicine.
  • Inform your doctor if you experience slow or fast heart rate, chest pain, shortness of breath.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Macquin 500mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Macquin 500mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Macquin 500mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Macquin 500mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Macquin 500mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Macquin 500mg Tablet in patients with liver disease.

Interaction with drugs

Taking Macquin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Quinidine.
Life-threatening

Aripiprazole (Oral Route)

Do not consume Aripiprazole with Quinidine.
Life-threatening

Escitalopram Oxalate (Oral Route)

Do not consume Escitalopram Oxalate with Quinidine.
Life-threatening

Pimozide (Oral Route)

Do not consume Pimozide with Quinidine.
Life-threatening

Haloperidol (Oral Route)

Do not consume Haloperidol with Quinidine.

Frequently asked questions

Yes. Although Macquin 500mg Tablet is used to treat certain abnormal heart rhythms, it can sometimes cause new or worsening rhythm disturbances, including serious ventricular arrhythmias. Seek immediate medical attention if you experience fainting, severe dizziness, chest pain or a new irregular heartbeat.
Yes. Macquin 500mg Tablet may cause ringing in the ears, hearing changes, dizziness or visual disturbances. These symptoms may be signs of a condition called cinchonism, which can occur with quinidine toxicity. Inform your doctor if you experience them.
Yes. Macquin 500mg Tablet may lower blood pressure and cause dizziness or light-headedness, particularly when standing up. Inform your doctor if these symptoms are severe or persistent.
Low blood sugar has been reported with quinidine use. Watch for symptoms such as sweating, shakiness, hunger, dizziness or confusion, and inform your doctor if they occur.
Tell your doctor about all medicines you take, including prescription medicines, over-the-counter products and supplements. Some medicines can increase the risk of serious heart rhythm disturbances or alter quinidine levels. Do not start or stop any medicine without medical advice.
No. Do not stop or change the dose on your own. Your doctor will decide whether treatment should continue, change or stop based on your condition and monitoring results.

Fact Box

Chemical Class

Cinchona alkaloids

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Class I Antiarrhythmics

References

  1. Sampson KJ, Kass RS. Anti-Arrhythmic Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 843-45.
  2. Nattel S, Gersh BJ, Opie LH. Antiarrhythmic Drugs and Strategies. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 273-74.
  3. Hume JR, Grant AO. Agents Used in Cardiac Arrhythmias. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 237-38.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1186-87.
  5. Quinidine gluconate. Philadelphia, Pennsylvania: Mutual Pharmaceutical Company, Inc.; 2009. [Accessed 20 Mar. 2019] (online) Available from:
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
  7. Quinidine [Prescribing information]. Epic Pharma, LLC; 2023. [Accessed 3 Nov 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torque Pharmaceuticals Pvt Ltd
Address: C-83, Industrial Area, Phase 7, Mohali, Punjab (INDIA) – 160055

Vendor Details

Country of origin: India
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