Levitrend 500mg Injection

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 31 Mar 2026 | 02:31 PM (IST)

Levitrend 500mg Injection is an anti-epileptic medicine used to treat seizures (fits) in epilepsy. It can be used alone or along with other medicines. It helps to prevent seizures for as long as you continue to take it.

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General Information

Contains

Levetiracetam (500mg)

Marketer

Starus Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Levitrend 500mg Injection is given as an infusion (slow drip) into a vein under the supervision of a healthcare professional. It is generally used for short-term control of seizures when treatment with oral medication is not feasible (eg. when the patient is unconscious). You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. Your doctor is likely to prescribe you oral medicines for long-term seizure control, after treatment with this injection has been completed.

Some common side effects of this medicine include dizziness, headache, infection, irritation, nasopharyngitis, sleepiness, aggressive behavior, and decreased appetite. You may also experience behavioral changes, aggressive behavior, irritation, agitation, etc. Side effects are more common during the first few days and usually lessen as your body gets used to the medicine. Most of these side effects do not need medical attention, but some of them can be serious. Let your doctor know right away if you have developed an allergic reaction (hives, itching, weakness, dizziness, difficulty in breathing, or swelling of face, tongue, and throat), a skin rash, or persistent behavioral changes like confusion, forgetfulness, feeling irritable, increased aggression or hostility. There may be ways of preventing or reducing them. A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse.

Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. Avoid alcohol while taking this medicine, as it may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested periodically while taking this medicine.

Uses of Levitrend Injection

Benefits of Levitrend Injection

Treatment of Epilepsy/Seizures
Levitrend 500mg Injection belongs to a group of medicines called anticonvulsants (or anti-epileptics). It works by slowing down electrical signals in the brain which cause seizures (fits). This medicine can be used to control various types of seizures—myoclonic, partial-onset, and primary generalized tonic-clonic (or grand mal). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. You should continue taking it even if you feel well and are not having any seizures. Missing doses may trigger a seizure. Do not stop using this medicine until your doctor advises you.

Side effects of Levitrend Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Levitrend

Sleepiness
Dizziness
Decreased appetite
Fatigue
Headache
Behavioral changes
Irritation
Aggressive behavior
Agitation
Infection
Nasopharyngitis (inflammation of the throat and nasal passages)

How to use Levitrend Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Levitrend Injection works

Levitrend 500mg Injection is an antiepileptic medication. It works by attaching to specific sites (SV2A) on the surfaces of nerve cells. This suppresses the abnormal activity of the nerve cells in the brain and prevents the spread of electrical signals that cause seizures.

All substitutes for Levitrend 500mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

It is given as IV infusion under the supervision of a doctor.
Some healthy tips to prevent seizures:
- Take a healthy diet along with regular exercise.
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/ laptop.
- Take your medication on time.
It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Inform your doctor if you have ever been diagnosed with kidney disease. The dose of your medicine may need to be adjusted.
Your doctor has prescribed Levitrend 500mg Injection to reduce the frequency of seizures.
Levitrend 500mg Injection should be taken at the same time every day to maintain consistent levels in your body.
Do not stop using Levitrend 500mg Injection without talking to your doctor, even if you feel better.
It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Avoid consuming alcohol when taking the Levitrend 500mg Injection as it may cause excessive drowsiness and calmness.
Inform your doctor if you have ever been diagnosed with kidney disease. The dose of your medicine may need to be adjusted.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Levitrend 500mg Injection should be taken regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Take a healthy diet along with regular exercise.
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/ laptop.
- Take your medication on time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Levitrend 500mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Levitrend 500mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Levitrend 500mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Monitor the baby for sleepiness and adequate weight gain.

Driving

UNSAFE

Levitrend 500mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Levitrend 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Levitrend 500mg Injection is safe to use in patients with liver disease. No dose adjustment is recommended.
However, a lower dose may be advised in patients with severe liver disease.

Interaction with drugs

Taking Levitrend with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Carbamazepine (Oral Route)

Talk to your doctor if you experience blurred vision, uncontrolled eye movement, lack of muscle control, and drowsiness. Carbamazepine may reduce blood levels of Levetiracetam.

Moderate

Fosphenytoin (Injection Route)

Talk to your doctor if you experience blurred vision, uncontrolled eye movement, lack of muscle control, and drowsiness. Fosphenytoin may reduce blood levels of Levetiracetam.

Moderate

Methotrexate (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Methotrexate (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Phenytoin (Injection Route)

Talk to your doctor if you experience blurred vision, uncontrolled eye movement, lack of muscle control, and drowsiness. Phenytoin may reduce blood levels of Levetiracetam.

Frequently asked questions

Will the use of Levitrend 500mg Injection affect my fertility?

Levitrend 500mg Injection is not known to affect fertility in males or females. However, talk to your doctor if you are facing fertility issues during the treatment with this medicine.

Can the use of Levitrend 500mg Injection cause sleepiness?

Yes, Levitrend 500mg Injection can make you feel sleepy. Therefore, during the initial phase of treatment, avoid driving, operating machinery, working at heights, or participating in potentially dangerous activities until you know how this medicine affects you.

I have gained weight since I started taking Levitrend 500mg Injection. Is it because of Levitrend 500mg Injection? What should I do?

Weight gain is an uncommon side effect of Levitrend 500mg Injection. However, the response may vary from person to person. To prevent weight gain you should take a healthy balanced diet, avoid snacking, cut down on high-calorie food items, include more vegetables and fruits in your diet, and exercise regularly. If you still have issues with your weight, consult your doctor.

How long does Levitrend 500mg Injection take to show its effect?

Levitrend 500mg Injection may take a few weeks to start working properly since the dose is increased slowly. Your seizures may continue until Levitrend 500mg Injection starts working completely.

For how long do I need to take Levitrend 500mg Injection?

You should continue to take Levitrend 500mg Injection for as long as your doctor advises you to. Do not stop taking it suddenly because this may increase the frequency of seizures which may be difficult to control.

Can I drink alcohol with Levitrend 500mg Injection?

Yes, you may drink alcohol while taking Levitrend 500mg Injection. Alcohol itself does not affect the way Levitrend 500mg Injection works. However, alcohol can increase the sleepiness or dizziness that occur as side effects of Levitrend 500mg Injection in some individuals. Therefore, you should avoid alcohol while taking Levitrend 500mg Injection until you know how it affects you.

Will I get addicted to Levitrend 500mg Injection if I use it for a long time?

No, Levitrend 500mg Injection is not habit-forming. No physical or psychological dependence has been reported with Levitrend 500mg Injection. Consult your doctor if you experience any side effects.

What symptoms can occur if someone takes an excess of Levitrend 500mg Injection?

Taking an excess of Levitrend 500mg Injection may cause sleepiness, agitation, aggression, a decrease of alertness, inhibition of breathing, and even a state of coma. In case of an overdose, immediate medical care should be provided to the patient in a nearby hospital.

Fact Box

Chemical Class

Alpha amino acid derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Synaptic Vesicle 2A (SV2A) Protein Ligands- Antiepileptic Drugs (AEDs)

References

Stahl SM, editor. Levetiracetam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 333-36.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 600.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 411.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 789.
Levetiracetam [FDA Label]. Albuquerque, New Mexico: Cardinal Health; 2006. [Accessed 25 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Levetiracetam. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
Levetiracetam [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2021. [Accessed 08 Jul. 2023]. (online) Available from:
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Levetiracetam. [Updated 2022 Nov 30]. [Accessed 08 Jul. 2023]. (online) Available from:
National Health Service. Pregnancy, breastfeeding and fertility while taking levetiracetam. [Last Reviewed: 10 May 2022]. [Accessed 08 Jul. 2023]. (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Starus Pharmaceuticals
Address: STARUS PHARMACEUTICALS PRIVATE LIMITED, 1st FLOOR, MOPARTHY TOWERS, LANE BESIDE KARACHI BAKERY, ROAD NO:1, BANJARA HILLS, HYDERABAD-500034, INDIA

Vendor Details

Country of origin: India

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Levitrend 500mg Injection

Save more with additional offers

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Levitrend Injection

Benefits of Levitrend Injection

Side effects of Levitrend Injection

How to use Levitrend Injection

How Levitrend Injection works

All substitutes for Levitrend 500mg Injection

Keppra Injection

Torleva Injection

Epicetam Injection

Levihop Injection

Levetrapal 500mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Carbamazepine (Oral Route)

Fosphenytoin (Injection Route)

Methotrexate (Injection Route)

Methotrexate (Oral Route)

Phenytoin (Injection Route)

Frequently asked questions

Will the use of Levitrend 500mg Injection affect my fertility?

Can the use of Levitrend 500mg Injection cause sleepiness?

I have gained weight since I started taking Levitrend 500mg Injection. Is it because of Levitrend 500mg Injection? What should I do?

How long does Levitrend 500mg Injection take to show its effect?

For how long do I need to take Levitrend 500mg Injection?

Can I drink alcohol with Levitrend 500mg Injection?

Will I get addicted to Levitrend 500mg Injection if I use it for a long time?

What symptoms can occur if someone takes an excess of Levitrend 500mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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