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Lenvatinib Capsule

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Mar 2026 | 11:29 AM (IST)
Lenvatinib Capsule is used to treat certain types of cancers like differentiated thyroid cancer, liver cancer, kidney cancer, and endometrial cancer. It works by blocking specific proteins that promote cancer cell growth and spread, and reducing tumor size in affected individuals.
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Lenvatinib Capsule
Lenvatinib Capsule
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General Information

The content is shown in English
Lenvatinib Capsule image
Lenvatinib Capsule image
Lenvatinib Capsule image
Lenvatinib Capsule image

Product introduction

Lenvatinib Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will determine the right dose and how often you should take it. This will depend on what you are being treated for. The dosage may change over time. You should take it exactly as your doctor has advised. Taking it the wrong way or taking too much can cause very serious side effects.


Common side effects of this medicine include high blood pressure, bleeding, and diarrhea. It might also cause severe headaches and loss of appetite. If any of these side effects persist or worsen, consult your doctor. They may be able to suggest ways to manage the side effects.


Before taking Lenvatinib Capsule, tell your doctor if you have heart disease, liver, or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect or be affected by this medicine, so let your doctor know about all the medicines you are taking. Pregnant and breastfeeding women should consult their doctors before starting this medicine, as it may cause harm to the developing baby.

Benefits of Lenvatinib Capsule

Differentiated Thyroid cancer
Thyroid is a butterfly-shaped gland located at the base of your neck. Your thyroid produces hormones that regulate your heart rate, blood pressure, body temperature and weight. Thyroid cancer occurs in the cells of the thyroid and it might not cause any symptoms at first. Lenvatinib Capsule restricts the oxygen supply of the cancer cells and stops its growth as well as further spread. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
Treatment of Kidney cancer
Lenvatinib Capsule, when used in combination with other anticancer medicines, is used to treat kidney cancer. This combination helps slow the growth and spread of cancer cells, which can contribute to improved treatment outcomes. It may help patients live longer and maintain a better quality of life during therapy.
Liver cancer
Lenvatinib Capsule is used to treat liver cancer when surgery is not possible. It helps control the disease by slowing its progression and reducing tumor size, which can improve survival and ease symptoms. This gives patients better disease management and helps maintain their quality of life.
Treatment of Endometrial cancer
Lenvatinib Capsule is used in the treatment of certain types of endometrial cancer, especially when the disease has spread or returned after initial therapy. It may help in managing the condition by slowing disease progression and is often used in combination with other treatments based on clinical guidance.

Side effects of Lenvatinib Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lenvatinib
  • High blood pressure
  • Diarrhea
  • Increased bleeding tendency

How to use Lenvatinib Capsule

Take this medicine in the dose and duration as advised by your doctor. Lenvatinib Capsule may be taken with or without food.

How Lenvatinib Capsule works

Lenvatinib Capsule is a tyrosine kinase inhibitor. It works by blocking the oxygen and nutrient supply to cancer cells, due to which they stop growing. And Lenvatinib Capsule helps in treating thyroid cancer.

Quick tips

  • Take it with or without food, preferably at the same time each day.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure, such as severe headache, confusion, problems with your eyesight, nausea, or vomiting.
  • It may cause serious bleeding problems. Inform your doctor if you get headaches or stomach pain or if you notice blood in your urine or stools.
  • Consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lenvatinib Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Lenvatinib Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Lenvatinib Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Lenvatinib Capsule may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Lenvatinib Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Lenvatinib Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Lenvatinib with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Thioridazine (Oral Route)

Do not consume Thioridazine with Lenvatinib.
Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Lenvatinib.
Life-threatening

Pimozide (Oral Route)

Do not consume Pimozide with Lenvatinib.
Life-threatening

Haloperidol (Oral Route)

Do not consume Haloperidol with Lenvatinib.
Life-threatening

Sotalol (Oral Route)

Do not consume Sotalol with Lenvatinib.

Frequently asked questions

To evaluate if Lenvatinib Capsule is effective, your doctor may assess your improvement through scans to monitor your tumor. Your doctor can let you know how well you are doing with Lenvatinib Capsule treatment and if there is any resolution of your tumor.
During Lenvatinib Capsule treatment, contact your doctor or go to the hospital immediately if you experience serious side effects. These may include high blood pressure, such as severe headaches or chest pain. You may also have heart problems like shortness of breath, swelling, or a fast heartbeat. Bleeding or blood in vomit or stool can occur. Signs of liver or kidney failure include yellowing of the skin, confusion, or dark urine. Other serious symptoms may include severe diarrhea or vomiting, seizures, vision changes, or confusion. These could be signs of posterior reversible encephalopathy syndrome (PRES), a rare brain condition.
No, never stop taking Lenvatinib Capsule on your own, as doing this may cause your cancer to worsen or spread to other parts of the body. Stopping abruptly without your doctor's advice may cause serious harm to your body.
You should avoid taking Lenvatinib Capsule if you are allergic to lenvatinib or any of its ingredients. Do not take it if you have uncontrolled high blood pressure, have had recent major surgery (as it may delay wound healing), have a hole in the stomach or intestine, or have recently had a stroke or heart attack. Always inform your doctor about your complete medical history before starting Lenvatinib Capsule treatment to ensure safer, better, and faster results.
Yes, your doctor will check blood pressure, liver function, kidney function, thyroid function, calcium level, protein in urine, heart function (possibly with ECGs), etc. These tests help catch serious problems early.
You should continue the Lenvatinib Capsule treatment until cancer has not properly resolved. Stopping or modification in the dose should only be done by a doctor once your cancer has resolved and shows no active symptoms.
Lenvatinib Capsule may impair fertility. Talk to your doctor about options like egg preservation before starting treatment.
While on Lenvatinib Capsule treatment, you should not have surgery unless your doctor tells you to stop the medicine as it can slow healing, tell your dentist before any dental work (it can increase the risk of jaw problems), and drink plenty of fluids to avoid dehydration, especially if you have diarrhea.

Fact Box

Chemical Class

Quinoline carboxylic acids

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Country of origin: India
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