Lefrin Drop

Phenylephrine (NA)

Genuine

Authenticity Assured

Prescription

required

Lefrin Drop is a decongestant. It is used to relieve symptoms of common cold such as blocked nose, runny nose, watery eyes, sneezing, and swelling.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 07 Apr 2026 | 11:10 AM (IST)

₹34.1 MRP ₹36.988% off

Gurgaon

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 75 with minimum cashback of Rs. 15

Earn cashback up to Rs.75 with Amazon Pay Later

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Pay with Amazon Pay Balance and get cashback up to Rs. 75 with minimum cashback of Rs. 15

Earn cashback up to Rs.75 with Amazon Pay Later

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback on minimum transaction of Rs.599/- with Mobikwik UPI.

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

General Information

Contains

Phenylephrine (NA)

Marketer

Cadila Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Lefrin Drop is best taken with food. Use it in the dose and duration as prescribed by your doctor. This medicine needs to be taken regularly to get the most benefit from it. Keep using it as prescribed even if your symptoms disappear. Before you take this medicine, let your doctor know about any other medicines you are taking. You should also tell your doctor if you have any problems with your heart, liver, or kidneys.

The most common side effects of taking this medicine include nausea, vomiting, and headache. While you are on treatment with this medicine, do not smoke as it can worsen your symptoms. Drinking alcohol can also affect how the medicine works and should be avoided. It is not recommended for pregnant women, however, it may be safe for breastfeeding mothers if the doctor prescribes it.

Uses of Lefrin Drop

Nasal congestion (blocked nose)
Conjunctivitis
Uveitis
Pupil dilation
Eye Irritation
Common cold

Benefits of Lefrin Drop

Common cold
Lefrin Drop is a combination medicine that effectively relieves symptoms of the common cold, such as a blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps loosen thick mucus, making it easier to cough out. It also shrinks the blood vessels and provides rapid relief that lasts for several hours. These actions make breathing easier.

Lefrin Drop is safe and effective. It usually starts to work within a few minutes, and the effects can last up to several hours. Take it as prescribed by your doctor, and do not stop using it unless you are advised otherwise.

How to use Lefrin Drop

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. Lefrin Drop should be taken with or after food.

How Lefrin Drop works

Lefrin Drop is a nasal decongestant. It works by narrowing the small blood vessels, which provide temporary relief from congestion or stuffiness in the nose.

All substitutes for Lefrin Drop

For information purposes only. Consult a doctor before taking any medicine.

Salin P Drop

by West-Coast Pharmaceutical Works Ltd

₹25.24/drop

32% cheaper

Quick tips

You have been prescribed Lefrin Drop for the treatment of common cold symptoms.
Lefrin Drop can make you restless, so don't take it too close to bedtime.
Always take Lefrin Drop with food.
Do not use this medicine without a doctor's advice if you are pregnant or breastfeeding.
Avoid drinking and smoking while taking Lefrin Drop.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Lefrin Drop. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Lefrin Drop during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Lefrin Drop should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

NOT RELEVANT

Not relevant, as Lefrin Drop is intended for use in hospitalized patients.

Kidney

CAUTION

Lefrin Drop should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Regular monitoring of blood pressure is advised for dose adjustment.

Liver

CAUTION

Lefrin Drop should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Lefrin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Phenylephrine. If concurrent use is essential, please consult your doctor.

Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Phenylephrine. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Phenylephrine. Please consult your doctor.

Severe

Selegiline (Oral Route)

Do not consume Selegiline with Phenylephrine. If concurrent use is essential, your doctor may monitor your blood pressure frequently.

Moderate

Linezolid (Oral Route)

Do not consume Linezolid with Phenylephrine. If concurrent use is essential, please consult your doctor. They may monitor your blood pressure frequently.

Moderate

Linezolid (Injection Route)

Do not consume Linezolid with Phenylephrine. If concurrent use is essential, please consult your doctor. They may monitor your blood pressure frequently.

Frequently asked questions

Is it safe to use Lefrin Drop?

Yes, Lefrin Drop is safe for most of the patients. However, in some patients, it may cause side effects like nausea, vomiting, headache, fatigue, dizziness, dryness in the mouth, sleepiness and allergic reaction. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.

Can the use of Lefrin Drop cause dizziness?

Yes, the use of Lefrin Drop can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better. Do not drive or use any machines. Consult your doctor if the side effect persist or worsen.

Can the use of Lefrin Drop cause nausea and vomiting?

Yes, the use of Lefrin Drop can cause nausea and vomiting. To avoid nausea one can take Lefrin Drop with milk, food or with antacids. If vomiting occurs, drink plenty of water or other fluids. Talk to your doctor if vomiting persists. You should let your doctor know if you are unable to drink water and there are signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Avoid taking fatty or fried foods along with this medication. Do not take any other medicine without consulting your doctor.

Fact Box

Chemical Class

1- hydroxy- 4- unsubstituted benzenoids

Habit Forming

Therapeutic Class

OPHTHAL

Action Class

Sympathomimetics- Alpha-1 (Nasal)

References

Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 295.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1110.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:

User feedback

What are you using Lefrin Drop for?

Nasal congestion (blocked nose)

100%

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cadila Pharmaceuticals Ltd
Address: Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Lefrin Drop

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Lefrin Drop

Benefits of Lefrin Drop

How to use Lefrin Drop

How Lefrin Drop works

All substitutes for Lefrin Drop

Salin P Drop

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Moclobemide (Oral Route)

Tranylcypromine (Oral Route)

Selegiline (Oral Route)

Linezolid (Oral Route)

Linezolid (Injection Route)

Frequently asked questions

Is it safe to use Lefrin Drop?

Can the use of Lefrin Drop cause dizziness?

Can the use of Lefrin Drop cause nausea and vomiting?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

What are you using Lefrin Drop for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests