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Last updated
28 Jun 2022 | 09:24 PM (IST)

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Lastet 50 Capsule

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Lastet 50 Capsule is used to treat different cancers of lung, and testicles. It is also sometimes used to treat some other kinds of cancer in both men and women. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.

Lastet 50 Capsule should be taken on an empty stomach, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you. It can lower your immunity, hence maintain distance from people suffering from cold and any other infection.

The most common side effect of this medicine includes low blood platelets, vomiting, nausea, hair loss, and anemia (low number of red blood cells).  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment.

Before taking this medicine, let your doctor know if you have liver or kidney disease, or if have been on radiation therapy. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may check you for blood cells and liver functioning while taking this medicine.

Benefits of Lastet Capsule

In Small cell lung cancer

Small cell lung cancer is a fast-growing type of lung cancer commonly caused by smoking that starts with small tumors in the lungs but eventually spreads to the other parts of the body as well. Lastet 50 Capsule helps treat such types of cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Testicular cancer

Testicular cancer is the cancer in the male organs called testicles, that make male hormones and sperm. The testicles are located inside a loose bag of skin (scrotum) underneath the penis. Lastet 50 Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. It is given as an injection by a doctor or nurse and should not be self-administered.

Side effects of Lastet Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lastet

  • Anemia (low number of red blood cells)
  • Decreased blood cells (red cells, white cells, and platelets)
  • Decreased white blood cell count
  • Diarrhea
  • Hair loss
  • Liver damage
  • Low blood platelets
  • Nausea
  • Rash
  • Stomatitis (Inflammation of the mouth)
  • Vomiting

How to use Lastet Capsule

Take this medicine in the dose and duration as advised by your doctor. Lastet 50 Capsule is to be taken empty stomach.

How Lastet Capsule works

Lastet 50 Capsule is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lastet 50 Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Lastet 50 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Lastet 50 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Lastet 50 Capsule does not usually affect your ability to drive.
Kidney
CAUTION
Lastet 50 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Lastet 50 Capsule may be needed. Please consult your doctor.
Use of Lastet 50 Capsule is not recommended in patients with end-stage kidney disease.
Liver
CAUTION
Lastet 50 Capsule should be used with caution in patients with liver disease. Dose adjustment of Lastet 50 Capsule may be needed. Please consult your doctor.
Use of Lastet 50 Capsule is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Lastet 50 Capsule
₹62.29/Capsule
Etoplast 50mg Capsule
Neon Laboratories Ltd
₹39.21/capsule
37% cheaper
Posid 50mg Capsule
Cadila Pharmaceuticals Ltd
₹49.5/capsule
21% cheaper
Etovel 50 Capsule
GLS Pharma Ltd.
₹55.25/capsule
11% cheaper
Etopa 50mg Capsule
Getwell Pharmaceutical Pvt Ltd
₹59.5/capsule
4% cheaper
Toposide 50mg Capsule
Chandra Bhagat Pharma Pvt Ltd
₹85/capsule
36% costlier

Quick tips

  • Lastet 50 Capsule should be taken on an empty stomach.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
  • Let your doctor know if you notice a skin rash, shortness of breath, difficulty breathing and swelling of the tongue.

Fact Box

Chemical Class
Podophyllotoxins Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkaloids-cytotoxic agents

Interaction with drugs

Taking Lastet with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Milorgen, Fosphen, Fosentin
Serious
Brand(s): Shinosun, Epikon, Sonal
Serious
Brand(s): Stoin, Marantin, Notian
Serious
Brand(s): Imudrops
Serious

Patient concerns

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What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Medical Oncology and Hematology
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
I seem to have lung cancer , becoz all the symptoms are same as lung cancer. I test my blood, they suggests me that it is highly probable to lung cancer. Sir what can i do now. This is in preliminary stage
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Do you think that lung cancer is diagnosed from blood
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1715-16.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 520-21.
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Etoposide. [Updated 2019 Jun 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  4. Etoposide. Sanderson Road Uxbridge Middlesex: Bristol-Myers Squibb Pharmaceuticals; 1983 [revised Nov. 2017]. [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

KHANDELWAL LABORATORIES PVT. LTD, 79/87 D.LADPATH, MUMBAI 400 033, INDIA
Country of origin: India
Expires on or after: October, 2022

A licensed vendor partner from your nearest location will deliver Lastet 50 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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