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Integrilin Injection

Eptifibatide (0.75mg/ml)
Genuine
Authenticity Assured
Prescription
required
Cold stored
Stored between 2-8°C
Integrilin Injection is a blood thinner which prevents formation of harmful blood clots. It is used in the treatment of a heart attack and also prevents the clotting of blood in the heart during an angioplasty (procedure to improve blood flow to the heart).

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 31 Mar 2026 | 02:31 PM (IST)
₹9431 MRP ₹102968% off 
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General Information

Contains

Eptifibatide (0.75mg/ml)

Marketer

Merck Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Integrilin Injection image
Integrilin Injection image

Product introduction

Integrilin Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

Use of this medicine may cause low blood platelets and increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool. It may also cause low blood pressure as a side effect. Your doctor will explain the benefits and risks associated with this medicine before it is administered.

This medicine is used with caution for some people. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Integrilin Infusion

Benefits of Integrilin Infusion

Prevention of Heart attack
It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Follow your doctor’s instructions carefully and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.
Prevention of Blood clots
Integrilin Injection prevents new blood clots from forming and prevents the existing ones from getting bigger. It works by blocking a substance in the body which is involved in blood clotting. Thus it helps your blood flow smoothly throughout the body. This can help reduce damage caused by clots in your lungs (pulmonary embolism), brain (stroke), heart (heart attack) or other blood vessels (thrombosis).

Side effects of Integrilin Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Integrilin
  • Bleeding
  • Decreased blood pressure

How to use Integrilin Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Integrilin Infusion works

Integrilin Injection is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots.

All substitutes for Integrilin Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • It is usually given by your nurse or doctor as an infusion (drip) into a vein.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
  • Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Integrilin Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Integrilin Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Integrilin Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

NOT RELEVANT
Not relevant, as Integrilin Injection is intended for use in hospitalized patients.
Kidney

Kidney

CAUTION
Integrilin Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Integrilin Injection is not recommended in patients with severe kidney disease.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Integrilin Injection in patients with liver disease.
Use of Integrilin Injection is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Integrilin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Apixaban (Oral Route)

Do not consume Apixaban with Eptifibatide. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate

Ticagrelor (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Moderate

Rivaroxaban (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Dabigatran Etexilate (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate

Desvenlafaxine (Oral Route)

If concurrent use is essential, watch out for bleeding and consult with your doctor immediately.

Frequently asked questions

Yes, Integrilin Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Integrilin Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
Integrilin Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Integrilin Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

BLOOD RELATED

Action Class

Glycoprotein IIb/IIIa Inhibitors

References

  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 871.
  2. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 355-56.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 485-46.
  4. Eptifibatide. Ferentino, Italy: Patheon Italia S.p.A.; 1998 [revised Mar. 2013]. [Accessed 18 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). Eptifibatide. [Accessed 18 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Merck Ltd
Address: L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India

Vendor Details

Country of origin: India
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