Medicine Overview of Grefac Injection
Grefac 20 mg Injection is used in the treatment and prevention of prevention of blood clots. It is also used in a heart attack.
Side Effects of Grefac are Low blood platelets, Increased liver enzymes, Anemia (low number of red blood cells), Bleeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Grefac 20 mg Injection is an anticoagulant. It works by inactivating certain blood-clotting proteins. This prevents the formation of blood clots and prevents blockages in the blood vessels of the body.
In Depth Information on Grefac Injection
- You have been prescribed Grefac 20 mg Injection for the prevention of blood clots.
Regular lab tests are not required to check whether it's working, unlike other similar medications.
- Grefac 20 mg Injection increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
- Inform your doctor if you are also taking other medicines that affect bleeding risk like aspirin and NSAIDs.
Notify your doctor if there is bleeding from gums, nose, or wounds that lasts more than 15 minutes, or if blood appears in urine, stool or vomit.
Do not stop taking the medication suddenly without talking to your doctor.
Grefac Injection related warnings
Interaction with alcohol is unknown. Please consult your doctor.
Grefac 20 mg Injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Grefac 20 mg Injection is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby.
Grefac 20 mg Injection is released in small amounts in the breast milk and amounts reaching the baby are also small, which would not be expected to cause any harmful effects to the baby.
Grefac 20 mg Injection does not usually affect your ability to drive.
Grefac 20 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Grefac 20 mg Injection may be needed. Please consult your doctor.
There is limited information available on the use of Grefac 20 mg Injection in patients with liver disease. Please consult your doctor.
However, cautious use is advised in patients with underlying liver disease.
If you miss a dose of Grefac 20 mg Injection, please consult your doctor.
Frequently asked questions about Grefac Injection
Q. Does it dissolve clots?
It does not dissolve existing clots
Q. Is Grefac a biosimilar?
Yes, Grefac is also available as biosmilar
Q. Is enoxaparin the same as heparin or lovenox?
Enoxaparin is not the same as heparin but both are used for similar indication. Lovenox is the brand name of enoxaparin
Q. Does it come in pill form?
It does not come in pill form
Q. Can I take paracetamol or ibuprofen with enoxaparin?
Enoxaparin is known to interact with paracetamol and ibuprofen and so should be taken only if prescribed by your doctor
Q. Is Grefac affect INR/ PTT/APTT/platelets?
Grefac increases the INR values (International normalized ratio; defines how long it takes for blood to clot when on anticoagulant therapy versus normal time) Partial thromboplastin time (PTT) or activated PTT (APTT) or platelets are not affected by Grefac.
Q. Is Grefac an anti-platelet, blood thinner/anticoagulant?
Grefac is an anticoagulant which does not allow blood to clot thus acting as a blood thinner but it is not anti-platelet
Q. Does Grefac contain pork?
Grefac is manufactured using pork intestine
Q. Does Grefac have to be refrigerated?
Grefac should not be refrigerated
Q. Does it contain benzyl alcohol?
It does contain benzyl alcohol
Q. Does Grefac make you tired?
Grefac is not known to cause tiredness as a side effect. Please consult the doctor when any side effects are observed while taking Grefac
Severely interacts with other drugs like
Taking Grefac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Clopidogrel: Clopinorm, Hanatrel, Clopido, Klopy, Flo, Clopizen, Clopilet, Clopifine, Clopace, MYO
Medicines with composition Oxyphenbutazone: Flanil
Medicines with composition Ticlopidine: Ticlopid, Tyklid
Medicines with composition Ramipril: Topram, Rigapril, Ram, Winpace, Artere, Beri, Topam, Xypril, Panpril, Ramison
Medicines with composition Valsartan: Valtan, Valent, Starval
Medicines with composition Metamizole / Dipyrone: Pyregin, Novalgin RC, Bral
Medicines with composition Irbesartan: Debipro, Sebri, Irbepex, Irovel
Medicines with composition Olmesartan: Olmirose, Olminir, Golme, Oltab, Olistor, Olque, Olran, Olsacare, Olmex, Olmecer
Medicines with composition Imidapril: Tanatril
Medicines with composition Nimesulide: Nimsun, Abinim, Nimulis, Neil, Zenee PR, Sanim, Renex, Nimoffin, Selide, Elide
Medicines with composition Enalapril: Enatol, AB-Pril, Inopril, Renin, Hiril, Lapril, Ecard, Enalcyp, Genlapril, Minipril
Medicines with composition Azilsartan: Aztra
Medicines with composition Benzydamine: Ready Rinse, Tantum, Mucobenz
Medicines with composition Losartan: Losin, Tosar, Closarten, L Sar, Rigapot, Lortan, Losarfine, Licosar, Lobeep, Aquazaar
Medicines with composition Telmisartan: Ontel, Telbind, Caditel, Telmicin, Rxtel, Telmiwell, Geotel, Fytel, Telmigold, Telga
Medicines with composition Lisinopril: K Pril, Lisinace, Lipril, Listril, Hipril, Lisoril
Medicines with composition Prasugrel: Prasunol, Prasuvas, Deklot, Prethromb, Prax, Ecogrel, Prasugrin, Prasusafe
Medicines with composition Aspirin / Acetylsalicylic acid: Disprin, M Spirin, Colsprin, Asprin, Loprin, Aspeeday, Acetyl Salicylic Acid, Delay Release Asprin
One of the following vendor pharmacies will deliver Grefac 20mg Injection: VNS, PMA, AGT, SNG, DHR, RSS, BAP, SHN, UVD, HLT, PRL, ANP, KHC, GFL, BBN, BDI, NDP, NXG, AXM, EAN, RKS, BHS, SHC, KLC, BJP, SLC, NSL, APS, IMC, SPD, AAR, NPH, HTS, VTR, DYL, RPI, SPF, BLP, AYU, UPA, SSS, JJE, BHA, KIS, JSL, WAD, JVO, SIO, 9MM, BHP, HCP, NTL, LHA, CLT, RDR, HWS, FRM, CPK, MPC, 4IT, GLM, EPS, ZVP, SGH, ENP, HEX, NAS, GHR, MRS, SRG, SWP, PSF, HMP, SAF, NLG, 1MH, RHS, SVS, BAL, TRP, NEO, BNA, MKT, CMD, LCC, VOP, HPP, AVL, BHM, OBS, DYG, TNH, LHP, CRN, VJS, AVB, DPL, SMS, SBA, BLS, ANT, DRA, VDH, ASP, PLT, OMV, GGL, JVN, ANS, ATL, DVH, TFP, SHD, HZF, HGI, SMN, STS, MKS, SSI, KHH, SVH, DGN, PVP, SGC, QTM, EMB, ATP, VHP, OWP, UMP, PPR, MLC, TAT, RGH, MAM, PRN, SLN, EQN, BLE, MJT, EVP, HNP, BMJ, RTL, MAP, AHP, QLF, MSD, BNT, HSM, GDA, MFN, GBL, RWP, SAA, TSS, AMR, RAC, KMC, HSP, ALC, ALY, HBV, PHN, AAY, JBT, KHD, AVS, HPC, FIP, SBL, ESY, RRP, PNQ, LMS, DHP, NVY, SNH, BIO, GPP, OLT, INC, DFP, STA, OIP, OHM, PRC, SCP, SDM, NTB, JHC, AYM, KIM, VSL, ARD, RHL, RVC, MBP, MDH, ZEL, WSI, SDE, GEO, AFT, BGS, ABP, GMA, HIP, RUS, SCH, DLP, BRC, SJP, DPP, JIV, WPL, BSN, RSA, BBS, RDH, ADT, THP, PTP, RPP, GNC, FGH, GTC, NNP, MDO, VRS, HAT, PTI, UHP, BNC, XMX, CMC, PEN, OWN, AMH, SWA, EEC, GLD, NVL, NLP, PNT, AYN, KNH, MIP, YMI, SBN, BJR, DLY, PWN, MAK, BTM, DZY, VSC, IAD, RHW, MAX, PHC, DAO, ZPR, WHL, WDE, IPL, TOM, PRT, IPP, WHP, USF