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25 Nov 2019 | 11:21 AM (IST)
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Grefac 20mg Injection


Overview

Introduction

Grefac 20mg Injection is known as an anticoagulant and is used to prevent and treat harmful blood clots. It stops existing clots getting any bigger and stops new ones forming. This helps prevent heart attack, and a type of clot called deep vein thrombosis (DVT) and pulmonary embolism.

Grefac 20mg Injection is injected under the skin by a doctor or nurse. It should not be injected into a muscle. The dose and length of treatment are based on your medical condition, your response to the medicine and what you are being treated for. It may also be based on your age and weight. It is important to keep using this medicine even if you feel no symptoms because it is preventing future harm. If you stop taking it, you could get a blood clot. While taking this medicine you should avoid doing things that increase your risk of bleeding or injury.

The most common side effect of this medicine is bleeding, including bruises. It can also cause a skin rash, itchy skin, headache and a lower number of red blood cells (anemia). A severe headache could be a sign of bleeding in the brain. A severe stomach ache could be a sign of bleeding in the stomach. Bleeding can be dangerous and may not be obvious. Look out for symptoms and tell your doctor if you are worried.

Before using this medicine, you should tell your doctor if you have high blood pressure, diabetes or you have had a recent stroke and you should not take it if you have any current bleeding. Some medicines should not be used with Grefac 20mg Injection. Tell your doctor what else you are taking to make sure it is safe. If you have low body weight, you may be at increased risk of bleeding and drinking alcohol can increase the risk of stomach bleeding. Consult your doctor about using this medicine if you are pregnant or breastfeeding.

Side effects of Grefac Injection

Common
  • Bleeding
  • Anemia (low number of red blood cells)
  • Headache
  • Itching

How to use Grefac Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Grefac Injection works

Grefac 20mg Injection is an anticoagulant. It works by inactivating certain blood-clotting proteins. This prevents the formation of blood clots and prevents blockages in the blood vessels of the body.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Grefac 20mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Grefac 20mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Grefac 20mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Grefac 20mg Injection is released in small amounts in the breast milk and amounts reaching the baby are also small, which would not be expected to cause any harmful effects to the baby.
Driving
SAFE
Grefac 20mg Injection does not usually affect your ability to drive.
Kidney
CAUTION
Grefac 20mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Grefac 20mg Injection may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Grefac 20mg Injection in patients with liver disease. Please consult your doctor.
However, cautious use is advised in patients with underlying liver disease.

What if you forget to take Grefac Injection?

If you miss a dose of Grefac 20mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Grefac 20mg Injection
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Quick Tips

  • You have been prescribed Grefac 20mg Injection for the treatment and prevention of blood clots.
  • Grefac 20mg Injection increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
  • Inform your doctor if you are also taking other medicines that increase the bleeding risk like aspirin and NSAIDs.
  • Inform your doctor if there is bleeding from gums, nose or wounds that lasts more than 15 minutes or if blood appears in your urine, stool or vomit.
  • Do not stop taking the medication suddenly without talking to your doctor.

Interaction with Drugs

Taking Grefac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Cantar, Candelong, Actinsar
SERIOUS
Brand(s): Capotril, Aceten, Angiopril
SERIOUS
Brand(s): Clopinorm, Hanatrel, Clopido
SERIOUS
Brand(s): Enatol
SERIOUS

Patient Concerns

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Suffering from pulmonary embolism (recurrent venous thrombosis)since 2014.Admitted in Asian hospital Faridabad for treatment in 2014(case summery is attached)now from one week suffering from breathlessness, congestion and cough and fainted on two occasions.l want to know the full treatment and wheather this would be treated by cardiologist or pulmonologist
Dr. Nabajit Talukdar
Heart Specialist
See a cardiologist. .can see me at medanta call 9XXXXXX
Hi Doctor good day I was diagnosed with pulmonary embolism in the year 2005 I was on warfarin for 6 months, till date I am on blood thinners anticoagulant tablets how long I can continue. If you stop taking anticoagulant tablets is there chance of getting a repeat episode. Do advice asap.
Dr. Anshum Aneja Arora
Lungs Specialist
Yes . Risk depend on your history which your doctor must have calculated . Usually if no cause is known treatment is given lifelong
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Do you have any questions related to Grefac 20mg Injection ?

FAQs

Q. How do you administer Grefac?

Grefac is a medicine which is injected beneath the skin. Fix the dose of the medicine and pinch the skin of your stomach between your finger and thumb to make a fold. After having cleaned the area, hold the syringe like a pencil and insert the full length of the needle into the skin fold. Inject the medicine and discard the syringe as instructed by your prescribing physician. Follow the instructions given by the healthcare provider strictly. Contact your doctor in case of any doubt or any reactions associated with the medicine.

Q. What are the conditions where I should be cautious before taking Grefac?

You must give a proper history to your doctor before you start taking Grefac. Inform your doctor if you have a heart valve fitted or have gastric ulcer, high blood pressure, diabetes, or kidney problems. You should also let your doctor know if you ever had a reaction to heparin or had a recent stroke, brain or spinal surgery. The chances of side effects and complications increase in presence of these conditions. Consult with your doctor and follow the instructions strictly.

Q. How to store Grefac injections?

Store Grefac injections at 25°C and do not freeze them. The multiple-dose vials should not be stored for more than 28 days after the first use. Discard the injection if you notice any particulate matter or abnormal color in the solution or any breach or damage in the syringe. Read the medicine package leaflet before using this medication and ask the pharmacist in case of any doubt.

Q. Can Grefac be used in heart attack?

Yes, Grefac is used in the treatment of chest pain and heart attack once the standard treatment has been provided to the patient. It is given along with another blood thinner like aspirin. Being a blood-thinning agent, it prevents the blood from clotting and prevents any further episodes and complications.

Q. Do you inject the air bubble in Grefac?

Yes, you should push the air bubbles into the site of injection. Removing the air bubbles leads to loss of the medicine thereby altering the prescribed dose.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 373-74.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 471.
  3. Enoxaparin sodium. Guildford, Surrey: SANOFI; 1997 [revised 08 Apr. 2018]. [Accessed 18 Mar. 2019] (online) Available from:External Link
  4. Drugs.com. Enoxaparin Pregnancy and Breastfeeding Warnings. [Accessed 18 Mar. 2019] (online) Available from:External Link
  5. U.S. National Library of Medicine. Enoxaparin. [revised 03 Dec. 2018]. [Accessed 18 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). Enoxaparin. [Accessed 18 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
A licensed pharmacy from your nearest location will deliver Grefac 20mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹159.22
MRP199.03  Get 20% OFF
This price is valid only on the orders above ₹500
1 ml in 1 prefilled syringe
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