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  • Rosuvastatin is used for the treatment of high cholesterol, high LDL, high triglycerides and low HDL in addition to diet, when response to non-medicine options (diet, exercise and weight loss) is not adequate.
  • It is also used to lower the risk of stroke, heart attack, or other heart complications in people who are at high risk of heart diseases, as an adjuvant to correction of the risk factors. 

How it works

Rosuvastatin belongs to a group of medications called statins (lipid-lowering agents) or HMG CoA reductase inhibitors. It acts by blocking the enzyme HMG CoA reductase which is important for  formation of cholesterol, thus, lowering the blood lipid levels.

Common side effects

Memory loss, Joint pain, Confusion, Constipation, Depression, Dizziness, Headache, Insomnia, Stomach pain


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Expert advice

  • Watch out for Muscle Symptoms. Please consult your doctor if you have any unexplained muscle pain,weakness or tenderness. 
  • Liver enzyme monitoring. Monitor liver enzymes before and after treatment. It can increase liver enzymes. 
  • Consult your doctor if you notice dark urine or yellowing of eyes or skin.
  • It can cause or worsen diabetes so appropiate precautions should be taken
  • Do not take antacids for atleast 2 hours before and after taking this drug.
  • Do not take rosuvastatin if you are allergic (hypersensitive) to rosuvastatin or any of the other ingredients of rosuvastatin.
  • Do not take this drug if you are pregnant or breast-feeding.

Frequently asked questions


Q. Is rosuvastatin lipophilic?
No. It is hydrophilic in nature.
Q. Is rosuvastatin safe?
Rosuvastatin is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is rosuvastatin gluten free?
Yes, rosuvastatin is gluten free 
Q. Is rosuvastatin better than simvastatin?
Rosuvastatin is better than simvastatin as this is longer acting, more potent and has less side effects.
Although, Rosuvastatin and simvastatin belong to same class of medication called as HMG CoA reductase inhibitor (or statins) with similar action

Content on this page was last updated on 27 October, 2016, by Dr. Varun Gupta (MD Pharmacology)