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16 Oct 2019 | 03:29 PM (IST)
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Grafotas 100 mg Capsule


Overview

Introduction of Grafotas Capsule

Grafotas 100 mg Capsule is used in combination with other medications to prevent transplant rejection. It treats the symptoms of rheumatoid arthritis (a disease, affecting the joints with pain and swelling), psoriasis (a skin disease) and atopic dermatitis (skin allergies).

Grafotas 100 mg Capsule should be taken in the dose and duration as advised by the doctor. But, before taking it report to doctor if you have known allergy to this medication. Your doctor may get regular blood tests done to check the levels of blood cells in your blood. Remember to inform doctor if you experience unexplained bleeding, fever, or general illness. Your doctor may advice for monitoring of kidney function.

It may cause nausea, headache and fatigue as its side effects. It may also cause increase in abnormal hair growth.

Grafotas Capsule side effects

Common
  • Headache
  • Nausea
  • Vomiting
  • Increased hair growth
  • High blood pressure
  • Renal dysfunction
  • Loss of appetite
  • Diarrhea
  • Tremor

How to use Grafotas Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Grafotas 100 mg Capsule is to be taken with food.

How Grafotas Capsule works

Grafotas 100 mg Capsule is an immunosuppressant. It works by suppressing your body’s immune response to help accept a newly transplanted organ (eg. liver, kidney, heart). In rheumatoid arthritis, this immunosuppressive effect reduces inflammation (swelling) of joints and limits joint damage. In psoriasis, it works by reducing the activity of certain immune cells that cause overproduction of skin cells, thus improving scaling and redness.

Grafotas Capsule related warnings

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Grafotas 100 mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Grafotas 100 mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Lactation
UNSAFE
Grafotas 100 mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Grafotas 100 mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Grafotas 100 mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Grafotas 100 mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Grafotas 100 mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Grafotas 100 mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.

What if you miss a dose of Grafotas Capsule?

If you miss a dose of Grafotas 100 mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Grafotas 100 mg Capsule
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8% costlier
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Expert Advice

  • Grafotas 100 mg Capsule is used to prevent organ rejection in transplant patients. 
  • It is also used to treat arthritis and immune disorders of the eyes, lungs, muscles, skin, nerves, and blood vessels.
  • It may take 3 to 4 months for the medication to work. Keep taking it as prescribed.
  • Your doctor may get regular blood tests done to check the levels of blood cells in your blood. Inform your doctor if you experience unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness. 
  • Your doctor may monitor your kidney function regularly. Drink 8 to 10 glasses of water per day to help with your kidney function.
  • Do not stop taking Grafotas 100 mg Capsule without talking to your doctor first.

Interaction with Drugs

Taking Grafotas with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Samwell
SERIOUS
Brand(s): Had Q
SERIOUS
Brand(s): Itraspan, Canzit, Cositra
SERIOUS
Brand(s): Begenta, Indogenta, Spagen
SERIOUS
Brand(s): Auxicasp, Canducid
SERIOUS
Brand(s): Stoin, Marantin
SERIOUS
Brand(s): Shinosun
SERIOUS
SERIOUS
Brand(s): Antep
SERIOUS

Patient Concerns

Questions Related to Grafotas

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My joint of my fingers and toes become stiff and painful in the morning while wake up and also feelung mild pain in my heart. I have been diagonised rheumatoid arthritis.
Dr. Akshat Goel
Bone & Joint Specialist
Please refer to a RheumatologistApply Dynapar QPS spray and take Tab Zerodol-SP twice daily and Tab Saaz 500mg twice daily and Tab HCQS-200 once daily
My mother has problem of rheumatoid arthritis since 2 years i want to ask can homeopathy cure dis problem if it can be treated than how many time it takes to cure and what treatment should be taken
Dr. Saurav Arora
Homeopathy
Dear sir this problem can surely be treated with homeopathy but as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly. The duration of treatment in different cases.
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User Feedback


FAQs

Q. Is Grafotas a steroid?

No, Grafotas is not a steroid. This belongs to a group of medicines known as immunosuppressive agents. It decreases the action of the body’s immune system.

Q. Can Grafotas cause weight gain?

Grafotas may either cause an increase or decrease in weight. However, the changes in weight are uncommon side effects of this medicine. Consult your doctor if these side effects worry you.

Q. Does Grafotas cause hair growth?

Yes, the use of Grafotas may cause abnormal hair growth (hypertrichosis) as a common side effect of Grafotas, though it does not affect everyone.

Q. Does Grafotas cause fatigue?

Yes, Grafotas may cause fatigue as a common side effect. However, fatigue could also be due to an underlying disease. Discuss with your doctor if this side effect worries you.

Q. Do I need to get any tests done while being treated with Grafotas?

Yes, the doctor may suggest tests to check the levels of Grafotas in your blood, especially if you have had a transplant. You may also be advised to get your blood pressure checked before the start of your treatment and regularly during treatment. In addition, liver and kidney function tests along with your blood lipids (fats), will be checked.

Q. Can Grafotas cause cancer?

Grafotas is known to suppress the immune system. This as a result, increases your risk of developing cancers, particularly of the skin and lymphoid system. You should limit your exposure to sunlight and UV light by wearing appropriate protective clothing. Sunscreen should be applied frequently with a high protection factor.

Q. What are the side effects of Grafotas?

Grafotas may cause side effects such as headache, diarrhea, heartburn, increased hair growth on the face, arms, or back, growth of extra tissue on the gums, acne, flushing, and uncontrollable shaking of a part of your body. You may also experience burning or tingling sensation in the hands, arms, feet, or legs, muscle or joint pain, cramps, pain or pressure in the face, ear problems, breast enlargement in men, depression and difficulty falling asleep or staying asleep.

Q. How should Grafotas be taken?

Take Grafotas strictly as advised by your doctor. The doctor will decide and carefully adjust your dose according to your medical requirements. It is important to keep a constant amount of Grafotas in the body, and hence, the medicine should be taken at the same time each day. Not only is the time of day important, but also when Grafotas is taken in relation to meals.

Q. How long do I need to take Grafotas?

Take Grafotas for as long as the doctor has advised. The duration of treatment depends on whether you are taking it after a transplant or for the treatment of other conditions. Usually, the treatment may last for 8 weeks if you are taking it for severe rash.

Q. What is Grafotas used for?

Grafotas is used in combination with other medications which are used to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have received kidney, liver, and heart transplants. These combination medicines also help to treat the symptoms of rheumatoid arthritis (a disease, affecting the joints with pain and swelling) in patients whose symptoms were not relieved by methotrexate alone, to treat psoriasis (a skin disease in which red, scaly patches form on some areas of the body), and atopic dermatitis (skin allergies).

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1821.
  2. Wallace JL, Sharkey KA. Pharmacotherapy of Inflammatory Bowel Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1358-59.
  3. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 630-31.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 340-42.
  5. Ciclosporine. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1983 [revised 24 Jul. 2015]. [A cessed 25 Jan. 2019].(online) Available from:External Link
  6. Drugs.com. Cyclosporine. [Accessed 06 Apr. 2019] (online) Available from:External Link
  7. Cyclosporine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation. [Accessed 06 Apr. 2019] (online) Available from:External Link
  8. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link
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