Author Details
Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated
15 Dec 2023 | 05:57 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Grafeel Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
arrow
arrow

Product introduction

Grafeel Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

Grafeel Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked to get regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.

The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat, and swelling around the face or neck.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Grafeel Injection

  • Prevention of Infections after chemotherapy

Benefits of Grafeel Injection

In Prevention of Infections after chemotherapy

Grafeel Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Grafeel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Grafeel

  • Bone pain
  • Weakness
  • Headache
  • Rash
  • Nausea
  • Increased lactate dehydrogenase level in blood
  • Vomiting
  • Increased uric acid level in blood
  • Oropharyngeal pain
  • Hair loss
  • Fatigue
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Cough
  • Breathing problems
  • Injection site reactions (pain, swelling, redness)

How to use Grafeel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Grafeel Injection works

Grafeel Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Grafeel Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Grafeel Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Grafeel Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Grafeel Injection may cause side effects which could affect your ability to drive.
Grafeel Injection may cause fatigue. This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Grafeel Injection is safe to use in patients with kidney disease. No dose adjustment of Grafeel Injection is recommended.
Liver
SAFE IF PRESCRIBED
Grafeel Injection is safe to use in patients with liver disease. No dose adjustment of Grafeel Injection is recommended.

What if you forget to take Grafeel Injection?

If you miss a dose of Grafeel Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Grafeel Injection reduces the risk of infection in people treated with chemotherapy.
  • It is usually given as a daily injection into the tissue just under the skin or into the vein. 
  • You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
  • Store it in the refrigerator, protect it from light, and don't shake it.
  • For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
  • Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
  • Use caution while driving or doing anything that requires concentration as Grafeel Injection may cause dizziness.
  • Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
  • Stop taking Grafeel Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Fact Box

Chemical Class
Granulocyte Colony-Stimulating Factor
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Granulocyte-colony stimulating factor (G-CSF)

Patient concerns

arrow
Plz check the report and reply She is my wife report one of hospital where operated the tumot operation and one of from delhi srl and last one from tmh mumbai After the diagnosis docror advice rediation now 1 st rediation therapy is finished and doctor giving now nublast 250mg tab So plz check the report and tell me as per the tata memorial final report what is the condition for patient She can live normal life or she can dead in ahead Doctor tells with my family she can live with treatment more than 1 to 2 years Is it right or wrong
Dr. Vijay Sharnangat
Medical Oncology and Hematology
You are on right treatmentAfter completion of radiation therapy you need to take chemotherapyThat tablet is the chemotherapy
What is symptomatic after chemotherapy for metastatic spine
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Back pain is main symptom which you can get after disease progression
arrow

User feedback


FAQs

Q. Is Grafeel Injection safe?

Grafeel Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Q. How does Grafeel Injection work?

Grafeel Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.

Q. What are the uses of Grafeel Injection?

Grafeel Injection is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation.

Q. Does Grafeel Injection cause cancer?

No, Grafeel Injection does not cause cancer.

Q. Why does Grafeel Injection cause bone pain?

The exact cause in unknown, but bone pain is a common side-effect of Grafeel Injection.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1074-75.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 545-46.
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Filgrastim. [Updated 2019 Jun 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., Village Malpur, P.O.Bhud, Baddi, Dist. Solan, H.P.
Country of origin: India

DISCONTINUED
We do not facilitate sale of this product at present

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.