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Colstim Injection

Filgrastim (300mcg)
Genuine
Authenticity Assured
Prescription
required
NPPA Regulated
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Cold stored
Stored between 2-8°C
Colstim Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)
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1 ml Injection
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General Information

Contains

Filgrastim (300mcg)

Marketer

Zydus Cadila

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Colstim Injection image
Colstim Injection image

Product introduction

Colstim Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked to get regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.

The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat, and swelling around the face or neck.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Colstim Injection

  • Prevention of Infections after chemotherapy

Benefits of Colstim Injection

Prevention of Infections after chemotherapy
Colstim Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Colstim Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Colstim
  • Nausea
  • Increased lactate dehydrogenase level in blood
  • Vomiting
  • Increased uric acid level in blood
  • Oropharyngeal pain
  • Hair loss
  • Fatigue
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Cough
  • Breathing problems
  • Bone pain
  • Weakness
  • Headache
  • Rash
  • Injection site reactions (pain, swelling, redness)

How to use Colstim Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Colstim Injection works

Colstim Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections. .

Quick tips

  • Colstim Injection reduces the risk of infection in people treated with chemotherapy.
  • It is usually given as a daily injection into the tissue just under the skin or into the vein. 
  • You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
  • Store it in the refrigerator, protect it from light, and don't shake it.
  • For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
  • Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
  • Use caution while driving or doing anything that requires concentration as Colstim Injection may cause dizziness.
  • Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
  • Stop taking Colstim Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Colstim Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Colstim Injection during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Colstim Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Colstim Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Colstim Injection may cause fatigue. This may affect your driving ability.
Kidney

Kidney

SAFE IF PRESCRIBED
Colstim Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Colstim Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Colstim with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Methotrexate (Injection Route)

Do not consume Filgrastim from 24 hours before or 24 hours after taking Methotrexate. Please consult with your doctor. Methotrexate may reduce the efficacy of Filgrastim.
Severe

Azathioprine (Oral Route)

Do not consume Filgrastim from 24 hours before and until 24 hours after taking Azathioprine.
Severe

Bendamustine (Injection Route)

Do not consume Filgrastim from 24 hours before and until 24 hours after taking Bendamustine.
Severe

Busulfan (Injection Route)

Do not consume Filgrastim from 24 hours before or 24 hours after taking Busulfan. Please consult with your doctor. Busulfan may reduce the efficacy of Filgrastim.
Severe

Busulfan (Oral Route)

Do not consume Filgrastim from 24 hours before or 24 hours after taking Busulfan. Please consult with your doctor. Busulfan may reduce the efficacy of Filgrastim.

Frequently asked questions

Colstim Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Colstim Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.
Colstim Injection is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation.
No, Colstim Injection does not cause cancer.
The exact cause in unknown, but bone pain is a common side-effect of Colstim Injection.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Granulocyte-Colony Stimulating Factor (G-CSF)

References

  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1074-75.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 545-46.
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Filgrastim. [Updated 2019 Jun 3]. [Accessed 18 Feb. 2020] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
  5. Filgrastim-txid. San Diego, CA: Tanvex BioPharma USA, Inc.; 2025.
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Fully sanitized facilities
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User feedback

Once A Day
41%
Once A Month
21%
Twice A Month
14%
Once A Week
14%
Thrice A week
3%
Twice A Week
3%
Alternate Day
3%
Infections after chemotherapy
100%
Excellent
67%
Average
33%
No Side Effect
100%
With or without food
100%
Expensive
67%
Average
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Colstim Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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