Goselin 3.6mg Injection is used for the treatment of prostate cancer in men and for breast cancer, endometriosis and uterine fibroids in women. In combination with some other medicine, it is used in the treatment of female infertility.

Goselin 3.6mg Injection is given as an injection under the skin by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Hot flashes are a very common side effect of this medicine. It can also cause sexual dysfunction, decreased libido, and urinary tract disorders. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. Women might experience vaginal bleeding during the initials days of treatment, which will stop on its own. Consult with your doctor, if this bothers you or does not go away.

Before taking this medicine, inform your doctor if you have a history of drinking alcohol and diabetes. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Goselin Injection

Benefits of Goselin Injection

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Goselin 3.6mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

In Breast cancer

Goselin 3.6mg Injection relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on cancer to stop its growth.

In Endometriosis

Endometriosis is a condition where tissue like the lining of the womb starts to grow in other places. The main symptoms include pain in your lower stomach or back, period pain, pain during and after sex, constipation, diarrhea and feeling sick. It can also make it difficult to get pregnant. Goselin 3.6mg Injection works by preventing the lining of your womb and any endometriosis tissue from growing too quickly. This will help relieve the symptoms you may have. This medicine needs to be taken regularly to be effective and you may need other medicines or procedures to help control endometriosis.

In Uterine fibroids

Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. Goselin 3.6mg Injection helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result, they decrease in size and also stop growing further. Take this medicine as advised by the doctor to get the most benefit.

In Female infertility

Goselin 3.6mg Injection is used in combination with other medicines to treat infertility in women. It helps to control the release of eggs from the ovaries. You should use the medicine as prescribed for it to be effective.

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Side effects of Goselin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Goselin

Decreased libido
Erectile dysfunction
Depression
Headache
Dizziness
Nausea
High blood pressure
Breast atrophy
Pain during sexual intercourse
Hot flushes
Sexual dysfunction
Urinary tract disorder
Lethargy
Pain
Edema (swelling)
Upper respiratory tract infection
Rash
Sweating
Decreased appetite
Chronic obstructive pulmonary disease (COPD)
Heart failure
Insomnia (difficulty in sleeping)
Vaginal inflammation
Emotional lability
Acne
Breast enlargement
Pelvic discomfort
Application site reactions (burning, irritation, itching and redness)
Pain during periods
Uterine bleeding

How to use Goselin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Goselin Injection works

Goselin 3.6mg Injection is a synthetic hormone. In men, it works by reducing the level of testosterone (male hormone) which causes regression of prostate tumor and improves symptoms. In women, it suppresses the level of estradiol (female hormone) which helps treat advanced breast cancer, endometriosis and uterine fibroids. It also reduces the thickness of the endometrium, which is the uterus lining, prior to surgery.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Goselin 3.6mg Injection. Please consult your doctor.

Pregnancy

UNSAFE

Goselin 3.6mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Goselin 3.6mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Goselin 3.6mg Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Goselin 3.6mg Injection is safe to use in patients with kidney disease. No dose adjustment of Goselin 3.6mg Injection is recommended.

Liver

SAFE IF PRESCRIBED

Goselin 3.6mg Injection is safe to use in patients with liver disease. No dose adjustment of Goselin 3.6mg Injection is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Goselin 3.6mg Injection is used for the treatment of prostate cancer in men and for breast cancer, endometriosis, and uterine fibroids in women.
It may also be used along with other medicines to treat infertility in women.
It is a prefilled syringe that is injected under the skin of the abdomen, every 28 days.
It may cause a reduction in bone mineral density and weakened bones. Your doctor may prescribe other medicines to reduce bone loss.
Inform your doctor if you start to feel depressed or have disturbing thoughts or feelings during treatment with this medicine.
Vaginal bleeding may occur in the first month after starting treatment and usually stops on its own. Inform your doctor if bleeding continues.

Fact Box

Chemical Class

GNRH Analogue

Habit Forming

Therapeutic Class

HORMONES

Action Class

GNRH agonists/analogue

Patient concerns

Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Not a symptom of prostate cancer

I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

May not be prostate cancer, it is only begnin enlargement of prostate.

Related lab tests

Anti Mullerian Hormone

Breast Cancer (CA 15.3/ ER/ PR)

Glycosylated Hemoglobin

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

Testosterone Total

Thyroid Stimulating Hormone

Related ayurvedic ingredients

Olive oil

Soybean

Garlic

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Goserelin acetate. Luton, Bedfordshire: AstraZeneca UK Limited; 2001 [revised 24 Jan. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
Goserelin acetate implant. Macclesfield, England: AstraZeneca UK Limited; 2009. [Accessed 02 Apr. 2019] (online) Available from:
UpToDate. Goserelin: Drug information. [Accessed 25 Jun. 2019] (online) Available from:
OncoLink. Goserelin Acetate. [Accessed 25 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: Bharat Serums & Vaccines Ltd

Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Country of origin: India

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Goselin 3.6mg Injection

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