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Genotropin Injection

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Genotropin Injection is a medicine used in the treatment of acromegaly, carcinoid tumors, and bleeding esophageal varices. It works by blocking certain hormones in the body as well as decreasing the bleeding from food pipe by narrowing the blood vessels.
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General Information

Contains

Somatostatin (5.3mg)

Marketer

Pfizer Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Genotropin Injection image
Genotropin Injection image

Product introduction

Genotropin Injection is given by a healthcare professional. You should not self-administer this medicine at home. Your doctor will decide the dose and how often you should take them. You should use it regularly to get the most benefit from the medicine. Do not stop using the medicine even if you feel better unless the doctor tells you so.

Using this medicine may cause few common side effects such as diarrhea, abdominal pain, nausea, constipation, flatulence, and headache. Let your doctor know if any of these side effects do not go away or get worse.

Before using this medicine, inform your doctor if you have problems with your liver. You should also tell your doctor all the other medicines you are taking. Your doctor may monitor your blood glucose regularly while on treatment with this medicine.

Uses of Genotropin Injection

  • Acromegaly
  • Bleeding esophageal varices
  • Carcinoid tumours

Benefits of Genotropin Injection

Acromegaly
Acromegaly is a hormonal disorder caused by excess growth hormone, leading to enlarged bones and tissues, especially in the hands, feet, and face. Genotropin Injection helps by reducing the release of growth hormone, which helps control symptoms and prevent complications associated with the condition.
Bleeding esophageal varices
Bleeding esophageal varices are swollen veins in the esophagus that can rupture and cause serious bleeding, often seen in patients with liver disease. Genotropin Injection helps reduce blood flow to these veins, effectively controlling bleeding and lowering the risk of further complications.
Carcinoid tumours
Carcinoid tumors are slow-growing tumors that can release hormones into the body, causing flushing, diarrhea, and other issues. Genotropin Injection aids in controlling the symptoms by suppressing the secretion of these excess hormones, improving patient comfort and quality of life.

Side effects of Genotropin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Genotropin
  • Diarrhea
  • Abdominal pain
  • Constipation
  • Flatulence
  • Headache
  • Increased glucose level in blood
  • Injection site reaction
  • Gallstones

How to use Genotropin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Genotropin Injection works

Genotropin Injection works by blocking the effects of certain natural hormones in the body such as serotonin and growth hormone. It also decreases bleeding from food pipe by constricting (narrowing) the blood vessels.

Quick tips

  • Genotropin Injection helps treat acromegaly and certain hormone-producing tumors of stomach, liver, and pancreas.
  • It is given as an injection under the skin or into a vein.
  • It may temporarily cause pain at the site of injection. You can relieve this by gently rubbing the site of injection for a few seconds afterwards. 
  • When used long term, your doctor may monitor your thyroid function, gallbladder function, liver function and vitamin b12 levels regularly.
  • Inform your doctor if you are taking medicines to control your blood pressure or if you are diabetic.
  • Women who do not wish to conceive should practice an effective method for contraception while taking this medication.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Genotropin Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Genotropin Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Genotropin Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Genotropin Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Genotropin Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Genotropin Injection in patients with liver disease.

Interaction with drugs

Taking Genotropin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Ivabradine (Oral Route)

Monitoring of blood pressure is recommended. Your doctor may adjust the dose if required.
Moderate

Digoxin (Injection Route)

Somatostatin may increase absorption of Digoxin, potentially enhancing its effects or side effects.
Mild

Miglitol (Oral Route)

Monitoring of blood glucose level is recommended.
Mild

Dapagliflozin (Oral Route)

Monitoring of blood glucose level is recommended.
Mild

Human insulin (Injection Route)

Monitoring of blood glucose level is recommended.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Somatostatin Analogues (SSAs)

References

  1. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1094.
  2. ScienceDirect. Somatostatin. [Accessed 04 Apr. 2019] (online) Available from:
  3. Sodium Iodide. Kirkland, Quebec: Draximage, Inc. [Accessed 04 Apr. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 3 Apr. 2019] (online) Available from:
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User feedback

Acromegaly
50%
Others
50%
Poor
67%
Average
33%
Headache
25%
Vomiting
25%
Flatulence
25%
Diarrhea
25%
Empty stomach
100%
Expensive
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Vendor Details

Country of origin: India
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