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Fsprogest Gel

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 22 Sep 2025 | 02:25 AM (IST)
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The content is shown in English
Fsprogest Gel image
Fsprogest Gel image
Fsprogest Gel image

Benefits of Fsprogest Gel

Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other being is estrogen) used in this treatment. However, it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Treatment of Female infertility
Fsprogest Gel contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

How to use Fsprogest Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Fsprogest Gel works

Fsprogest Gel is a progesterone (female hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.

Quick tips

  • Fsprogest Gel is a natural progesterone available as a micronized formulation which helps in better absorption of this medicine.
  • It is used as a part of hormone replacement therapy generally in combination with an estrogen.
  • It may also be used in the treatment of problems related to menstrual periods such as amenorrhea (absence of periods).
  • It also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.
  • It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Fsprogest Gel is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking Fsprogest with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Chlorthalidone (Oral Route)

Monitor your blood pressure regularly and talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.
Moderate

Hydrochlorothiazide (Oral Route)

Monitor your blood pressure regularly and talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.
Moderate

Hydrochlorothiazide (Injection Route)

Monitor your blood pressure regularly and talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.
Mild

Glipizide (Oral Route)

Monitor your blood glucose levels.
Mild

Gliclazide (Oral Route)

Concurrent use may worsen blood sugar control.

Frequently asked questions

Fsprogest Gel contains progesterone, which is a natural female sex hormone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance. It may also be prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).
For best results, take it strictly as per the advice of your doctor. The dose and duration depend on your exact medical condition. It is recommended to use it at the same time each day to ensure consistent levels of medicine in your body.
If you miss the dose, you should take it as soon as possible. If it is almost the time for your next dose, do not take the missed dose, instead continue the usual dosing schedule. Do not take a double dose to make up for the for the missed one.
The common side effects are vaginal discharge, headache, feeling tired, stomach cramps, and breast tenderness. If any of the side effects bother you, please consult with your doctor.
Fsprogest Gel is a type of progesterone hormone which is extracted from plants, but its property matches with the human progesterone. This medicine undergoes a process called micronization where the size of the natural progesterone is reduced. The small size of the progesterone particles enhances its dissolution and absorption. This provides better availability of Fsprogest Gel in the body and decreases its side effects.
Fsprogest Gel is used to treat various disorders. It is given to women with secondary amenorrhea (no menstruation for 3 months in menstruating women). It is used to support pregnancy, prevent premature labor and treat bleeding disorders that may occur before menopause. It may be used as a part of fertility treatment and may be given as hormone replacement therapy after menopause. It is also given to relieve symptoms of premenstrual syndrome and painful bleeding like in dysfunctional uterine bleeding.
Yes, Fsprogest Gel can be taken every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month. However, the number of days for which you will need to take this medicine in each cycle will be suggested by your doctor depending upon your health condition.
Yes, Fsprogest Gel may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if Fsprogest Gel and estrogen are taken as a combined pill. However, it is advisable to consult your doctor before starting any hormonal therapy.
Yes, Fsprogest Gel is safer as compared to the normal synthetic progesterone. It is small in size which helps the body to absorb it easily. Because of its small size the risk of side effects like fluid retention, reduction of HDL cholesterol levels, headaches and mood disturbance are also very less. However, if any of these side effects bother you or persist for a longer duration, consult your doctor.
Progesterone is a very crucial hormone in fertility. It prepares the uterus for pregnancy and also helps maintain it. Fsprogest Gel (natural micronized form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent the abortions in some cases. It is also used to prevent premature labor.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Natural Progesterone

References

  1. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
  2. Apgar S, Greenberg G. Using Progestins in Clinical Practice. Am Fam Physician. 2000;62(8):1839-46. [Accessed 03 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Fertilesure Pharma
Address: Hirabaugh, Surat, Gujarat

Vendor Details

Country of origin: India
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