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Fonaxel Injection is an anticoagulant medicine used in the treatment of deep vein thrombosis (clot in veins of leg) and pulmonary embolism (clot in artery of lungs). It helps to prevent formation of harmful blood clots in blood vessels.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 09 Feb 2025 | 01:07 AM (IST)
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General Information

The content is shown in English
Fonaxel Injection image
Fonaxel Injection image

Product introduction

Fonaxel Injection also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries, or who have been bedridden for long. It is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

Use of this medicine may increase your risk of bleeding. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Fonaxel Injection

Side effects of Fonaxel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Fonaxel
  • Bleeding
  • Anemia (low number of red blood cells)

How to use Fonaxel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Fonaxel Injection works

Fonaxel Injection is an anticoagulant. It stops the action of a substance (clotting factor Xa) from working in the blood. This prevents the formation of unwanted blood clots (thrombosis) in the blood vessels.

Quick tips

  • Fonaxel Injection prevents the formation of blood clots in the blood vessels of legs or lungs.
  • It may make you feel dizzy, tired or weak. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
  • Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
  • Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
  • Fonaxel Injection prevents the formation of blood clots in the blood vessels of legs or lungs.
  • It is given by injection, usually under the skin (subcutaneously) of the lower abdominal area.
  • It may make you feel dizzy, tired or weak. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
  • Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
  • Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Fonaxel Injection.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Fonaxel Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Fonaxel Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Fonaxel Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CAUTION
Fonaxel Injection should be used with caution in patients with kidney disease. Dose adjustment of Fonaxel Injection may be needed. Please consult your doctor.
Use of Fonaxel Injection is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Fonaxel Injection should be used with caution in patients with severe liver disease. Dose adjustment of Fonaxel Injection may be needed. Please consult your doctor.

Interaction with drugs

Taking Fonaxel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Diclofenac (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe

Diclofenac (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe

Cilostazol (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe

Clopidogrel (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe

Prasugrel (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Frequently asked questions

Yes, Fonaxel Injection increases the risk of bleeding, and the affects of Fonaxel Injection may last for 4 days even after stopping this medicine. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Fact Box

Chemical Class

Synthetic Glucopyranoside

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Selective Factor Xa Inhibitors

References

  1. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 375-76.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 591-92.
  3. Fondaparinux sodium. Notre-Dame-de-Bondeville, France: Aspen NDB; 2014. [Accessed 18 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). Fondaparinux. [Accessed 18 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Fonaxel Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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