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MD (Pharmacology), MBBS
Last updated on:
03 Oct 2019 | 02:49 PM (IST)
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Folitrax 25 Injection

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Overview

Uses of Folitrax Injection

Folitrax Injection side effects

Common
  • Nausea
  • Vomiting
  • Loss of appetite
  • Dyspepsia
  • Abdominal pain
  • Increased liver enzymes
  • Stomatitis (Inflammation of the mouth)

How to use Folitrax Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Folitrax Injection works

Folitrax 25 Injection is an immunosuppressant. In rheumatoid arthritis, it works by decreasing the activity of body's immune system. This decreases swelling, reduces pain and stiffness, and improves function. In psoriasis, it works by slowing down the rapid growth of skin cells.

Folitrax Injection related warnings

Alcohol
UNSAFE
It is unsafe to consume alcohol with Folitrax 25 Injection Taking Methotrxate with alcohol increases the risk of liver damage.
Pregnancy
UNSAFE
Folitrax 25 Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Lactation
UNSAFE
Folitrax 25 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Folitrax 25 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Folitrax 25 Injection should be used with caution in patients with kidney disease. Dose adjustment of Folitrax 25 Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Folitrax 25 Injection should be used with caution in patients with liver disease. Dose adjustment of Folitrax 25 Injection may be needed. Please consult your doctor.
Use of Folitrax 25 Injection is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Folitrax 25 Injection
₹55/Injection
11% costlier
₹55/ml of Injection
11% costlier

Expert Advice

  • It  is given as an injection under the skin (subcutaneously), usually in the upper thigh or the abdomen.
  • Take it once a week, on the same day every week.
  • Drink plenty of liquids to stay hydrated while taking this  medication.
  • Always take folic acid as advised by your doctor. This will help lessen the side effects of this medicine.
  • It may take 6 to 8 weeks for Folitrax 25 Injection to work. Keep taking the medication as prescribed.
  • Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
  • It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.

Interaction with Drugs

Taking Folitrax with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Densol
SERIOUS
Brand(s): Nimsun, Abinim, Nimulis
SERIOUS
Brand(s): Ducort, Defmark, Zacdef
SERIOUS

Patient Concerns

Questions Related to Folitrax

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I am taking cartigen 1500 and ccm after detection minor osteoarthritis on my left knee. Sometime i feel extreme pain but i am able to walk properly. Will you suggest other medicines?
Dr. Akshat Goel
Bone & Joint Specialist
Take Tab Rosortho twice daily and Tab Conjoint (Medley) twice daily along with CartigenAlso ask your treating doctor about Hyaluronic acid injection
She has sicatica problem & joint pain.I consulted with doctor they gave tramadol,shelecal ,vitamin d3sachet & neugaba tablets.still no improvement in pain.we consulted again with doctor and he gave same prescription again even we told no improvement in condition of patient.I want to ask u are these are only medicines to treat this problem or lack interest of doctor please guide me for better treatment.
Dr. Vipul Aggarwal
Bone & Joint Specialist
Please send me knee X-raysOsteoarthritis is the most common reasonPlease start with quadriceps exercises and try to loose weight in case over weightYour X-rays are bad but I still feel u should try managing it without surgery at this stageA local injection in knee will benefit u
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User Feedback


FAQs

Q. Can Folitrax cause mouth ulcers?

Yes, in fact a sore mouth and mouth ulcers are sometimes side effects of Folitrax therapy. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Q. Why do I have to take folic acid with Folitrax?

Folic acid is required to make new cells in the body and Folitrax decreases the folic acid levels in the body. By taking folic acid some of the common side effects, like mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems can be reduced.

Q. Why do I need to take regular blood tests while taking Folitrax?

Regular blood tests will help your doctor to check your response to Folitrax and monitor you for side effects. You will need to regularly check your liver function and your blood counts -white blood cells, red blood cells and platelets. Your doctor may also order additional tests depending on the results.

Q. Can Folitrax use make me more prone to infections?

Folitrax may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports of serious lung infections with Folitrax use. If you have an active infection, Folitrax should be used with extreme caution.

Q. Can Folitrax affect fertility?

Yes, it may affect fertility in both males and females. There may be a decrease in sperm count in males and menstrual disturbances in females. These effects are reversible and disappear once the therapy is discontinued.

Q. What to do if I am planning to become pregnant and my husband is taking Folitrax?

You should avoid pregnancy if your husband is taking Folitrax. Also, avoid pregnancy for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

Related Products

Related Ayurvedic Ingredients

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
  3. Drugs.com. Methotrexate Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
A licensed pharmacy from your nearest location will deliver Folitrax 25 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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