Febuvas 40 Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 21 Sep 2025 | 05:27 PM (IST)

Febuvas 40 Tablet is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals that can appear around your joints leading to painful and swollen joints. This medicine helps to keep uric acid levels low.

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Febuxostat (40mg)

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General Information

Contains

Febuxostat (40mg)

Marketer

Crestmed Pharmaceuticals Private Limited

Storage

Store below 25°C

The content is shown in English

Product introduction

Febuvas 40 Tablet can be taken with or without food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because of the formation of more crystals in your joints. You can help yourself by making some changes to your diet (eg. avoiding alcohol and non-vegetarian foods) and drinking plenty of fluids.

Some of the common side effects of this medicine are liver function abnormalities, nausea, joint pain, and rashes. You may experience a temporary increase in the gout symptoms (rapid onset of severe pain, warmth, and redness in the joint) when you first start taking the medicine. However, do not stop taking the medicine. Your doctor may suggest some painkillers and additional medicines to help reduce or prevent these symptoms. Tell your doctor right away if you get any symptoms of liver disease like persistent nausea, dark urine, or yellowing of the eyes or skin.

Before taking this medicine, let your doctor know if you have any heart problems, stroke, thyroid problems, or kidney or liver problems. If you are pregnant or breastfeeding, this medicine is best avoided. Check with your doctor. You will need regular blood tests while taking this medicine to check that your liver is working properly.

Uses of Febuvas Tablet

Treatment of Gout

Benefits of Febuvas Tablet

Treatment of Gout
Febuvas 40 Tablet is used to prevent and treat gout. Gout is caused by too much uric acid in your body. When the level becomes too high, crystals may form in and around certain joints and your kidneys. This can cause sudden and severe pain, redness, warmth, and swelling. This medicine works by preventing crystals from forming and reducing the levels of uric acid in your blood. This makes it less likely that you will suffer the symptoms and make them milder if you do have them. It is usually for long-term treatment and should be taken regularly until the dose is completed.

Side effects of Febuvas Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Febuvas

Nausea
Skin rash
Abnormal liver function
Joint pain
Rash

How to use Febuvas Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Febuvas 40 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Febuvas Tablet works

Febuvas 40 Tablet is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

All substitutes for Febuvas 40 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Your doctor has prescribed Febuvas 40 Tablet to reduce episodes of gout attack.
Take it at the same time every day, with or without food.
Take plenty of fluids (2-3 litres) daily while on Febuvas 40 Tablet.
When you first start taking this medicine, you might have more gout attacks. Do not stop Febuvas 40 Tablet on having an acute attack of gout as that could make an attack worse.
Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
Stop taking this medicine and inform your doctor straight away if you have symptoms like rash, itchiness, difficulties in breathing, fever, or swelling of limbs or face.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Febuvas 40 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Febuvas 40 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Febuvas 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Febuvas 40 Tablet may cause side effects which could affect your ability to drive.
Febuvas 40 Tablet may cause dizziness, sleepiness, blurred vision, numbness or tingling sensation. This may affect your driving ability.

Kidney

CAUTION

Febuvas 40 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Febuvas 40 Tablet may be needed. Please consult your doctor.
Limited information is available regarding the use of Febuvas 40 Tablet in these patients.

Liver

CAUTION

Febuvas 40 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Febuvas 40 Tablet may be needed. Please consult your doctor.
Limited information is available regarding the use of Febuvas 40 Tablet in these patients.

Interaction with drugs

Taking Febuvas with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Rosuvastatin (Oral Route)

Do not consume Rosuvastatin with Febuxostat. If concurrent use is essential, watch out for symptoms such as unexplained muscle pain, tenderness or weakness and consult your doctor if you experience them. They may monitor and adjust the dose of Rosuvastatin as per the observations. Febuxostat may raise blood levels of Rosuvastatin.

Moderate

Aminophylline (Oral Route)

If concurrent use is essential, watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you experience them. They may monitor and adjust the dose of Aminophylline accordingly. Febuxostat may raise blood levels of Aminophylline.

Moderate

Aminophylline (Injection Route)

Moderate

Azathioprine (Oral Route)

Do not consume Febuxostat with Azathioprine. If concurrent use is essential, watch out for symptoms such as abdominal pain, blurred vision, flushing or discomfort and consult your doctor if you experience them. They may adjust your doses as per the observations. Febuxostat may raise blood levels of Azathioprine.

Moderate

Mercaptopurine (Oral Route)

If concurrent use is essential, watch out for symptoms such as abdominal pain, blurred vision, flushing or discomfort and consult your doctor if you experience them. They may adjust your doses as per the observations. Febuxostat may raise blood levels of Mercaptopurine.

Frequently asked questions

What is Febuvas 40 Tablet used for?

Febuvas 40 Tablet is used to treat gout in adults. It is mainly used in patients who did not respond to the treatment with allopurinol or who are not able to take allopurinol. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints. It causes sudden attacks of redness, swelling, pain, and heat in one or more joints.

What are the side effects of Febuvas 40 Tablet?

Febuvas 40 Tablet may cause common side effects such as abnormal liver test results, diarrhea, headache, rash, nausea, and even an increase in gout symptoms and localized swelling due to retention of fluids in tissues (edema). Whereas, the serious side effects of Febuvas 40 Tablet include heart problems, gout flares, liver problems, and severe skin and allergic reactions. Immediately inform your doctor if you experience any serious side effects.

How long should I take Febuvas 40 Tablet?

The dose and duration of Febuvas 40 Tablet vary from person to person and are decided by your doctor. It may take several months before Febuvas 40 Tablet begins to prevent gout attacks. Do not stop taking Febuvas 40 Tablet without the advice of your doctor even if you feel better.

What is the best time to take Febuvas 40 Tablet?

Febuvas 40 Tablet is advised to be taken once a day. It can be taken at any time of the day, but preferably at the same time each day so that you remember to take it every day. This will help maintain the levels of Febuvas 40 Tablet in the body. You can take this medicine with or without food.

Can Febuvas 40 Tablet cause kidney damage?

Febuvas 40 Tablet may affect kidneys in different ways, though it is quite uncommon. You may experience blood in the urine, frequent urination, kidney stones, abnormal urine tests (increased level of proteins in the urine), and a reduction in the ability of the kidneys to function properly. Rarely, it may cause changes or decrease in urine amount due to inflammation in the kidneys (tubulointerstitial nephritis). Consult your doctor if your kidney functions get further affected.

Can I stop taking Febuvas 40 Tablet on my own if I am fine and have no pain or swelling in joints?

No, do not stop taking Febuvas 40 Tablet without your doctor's advice even if you feel better. Discontinuation of medicine may increase the levels of uric acid. It may also worsen your symptoms due to the formation of new crystals of urate in and around your joints and kidneys.

What are the things which I need to know while taking Febuvas 40 Tablet?

You should be aware that Febuvas 40 Tablet may cause serious heart problems which can be life-threatening in some cases. The symptoms of heart problems include chest pain, shortness of breath or trouble breathing, dizziness, fainting or feeling light-headed, rapid or irregular heartbeat. It may also cause numbness or weakness in one side of your body, slurring of speech and sudden blurry vision, or sudden severe headache. Immediately inform your doctor and seek medical help if you experience any of these symptoms.

Can Febuvas 40 Tablet cause any liver problems?

Yes, Febuvas 40 Tablet use may cause liver problems. Your doctor may advise you to get regular blood tests done before and during treatment with Febuvas 40 Tablet to check how well your liver was working before and while taking this medicine. Inform your doctor if you notice symptoms such as fatigue, pain, or tenderness on the right side of the abdomen or loss of appetite for several days or longer. It may also cause changes in the color of urine (dark or tea-colored) and may make your skin or the white part of your eyes turn yellow (jaundice).

Fact Box

Chemical Class

Thiazole Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Xanthine Oxidase Inhibitors

Related lab tests

Creatinine

Creatinine - Spot

Uric Acid

References

Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 997-98.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 534-35.
Febuxostat. Wooburn Green, Buckinghamshire: A. Menarini Farmaceutica Internazionale SRL; 2008 [revised 29 Oct. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Febuxostat. Deerfield, Illinois: Takeda Pharmaceuticals America, Inc.; 2009. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Crestmed Pharmaceuticals Private Limited
Address: 32/49 A&B,Madathil Parambil Building, Puthiyakavu, Thrippunithura Ernakulam Ernakulam Kl 682301 In

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Febuvas 40 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Febuvas Tablet

Benefits of Febuvas Tablet

Side effects of Febuvas Tablet

How to use Febuvas Tablet

How Febuvas Tablet works

All substitutes for Febuvas 40 Tablet

Febuvel 40mg Tablet

Febutax 40 Tablet

Febutec 40 Tablet

Foxstat 40 Tablet

Febumac 40 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Rosuvastatin (Oral Route)

Aminophylline (Oral Route)

Aminophylline (Injection Route)

Azathioprine (Oral Route)

Mercaptopurine (Oral Route)

Frequently asked questions

What is Febuvas 40 Tablet used for?

What are the side effects of Febuvas 40 Tablet?

How long should I take Febuvas 40 Tablet?

What is the best time to take Febuvas 40 Tablet?

Can Febuvas 40 Tablet cause kidney damage?

Can I stop taking Febuvas 40 Tablet on my own if I am fine and have no pain or swelling in joints?

What are the things which I need to know while taking Febuvas 40 Tablet?

Can Febuvas 40 Tablet cause any liver problems?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Creatinine

Creatinine - Spot

Uric Acid

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests