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Epsolin 100 Tablet

Phenytoin (100mg)

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Epsolin 100 Tablet is a prescription medicine used to treat and prevent epilepsy (seizures). It controls seizures by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information

Contains

Phenytoin (100mg)

Marketer

Zydus Cadila

Storage

Store below 30°C

The content is shown in English

Product introduction

Epsolin 100 Tablet can be used alone or in combination with other medicines. It should be taken in the dose and duration as advised by your doctor. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine, unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.

The most common side effects of this medicine include skin involuntary eye movement, lack of coordination, slurred speech, mental confusion, nausea, vomiting, constipation, and rash. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects.

Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression or suicidal thoughts. Also let your healthcare team know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, Epsolin 100 Tablet can be taken if it is clearly needed but the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.

Uses of Epsolin Tablet

Treatment and prevention of Epilepsy/Seizures

Benefits of Epsolin Tablet

Treatment and prevention of Epilepsy/Seizures
Epsolin 100 Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Side effects of Epsolin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Epsolin

Slurred speech
Confusion
Nystagmus (involuntary eye movement)
Coordination disorder
Sleepiness

How to use Epsolin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epsolin 100 Tablet may be taken with or without food.

How Epsolin Tablet works

Epsolin 100 Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

All substitutes for Epsolin 100 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
It may increase blood sugar levels. Inform your doctor if you are taking any medicines to treat diabetes.
It may cause swollen gum (gum hypertrophy), hence take care of oral or dental hygiene.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Epsolin 100 Tablet

Pregnancy

CONSULT YOUR DOCTOR

Epsolin 100 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Epsolin 100 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Epsolin 100 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Epsolin 100 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Epsolin 100 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Epsolin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Ticagrelor (Oral Route)

Do not consume Ticagrelor with Phenytoin. Phenytoin may reduce blood levels of Ticagrelor.

Severe

Ranolazine (Oral Route)

Do not consume Ranolazine with Phenytoin. Phenytoin may reduce blood levels and efficacy of Ranolazine.

Severe

Aripiprazole (Oral Route)

If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses as per the observations. Phenytoin may reduce blood levels of Aripiprazole.

Severe

Lorlatinib (Oral Route)

Do not consume Lorlatinib with Phenytoin. Phenytoin may reduce blood levels of Lorlatinib.

Severe

Acenocoumarol (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

For how long does Epsolin 100 Tablet stay in your system?

On an average, Epsolin 100 Tablet may stay in your system for 5-6 days. This duration varies from person to person. In some cases, it may stay for about 9-10 days.

What happens if I stop taking Epsolin 100 Tablet?

Suddenly stopping Epsolin 100 Tablet may cause non-stop seizures (called status epilepticus), which can endanger life. Do not stop taking the medicine without consulting your doctor. If required, your doctor will slowly reduce the dose before stopping it completely.

What are the symptoms that occur if I take more than the recommended dose of Epsolin 100 Tablet? Can I die from Epsolin 100 Tablet overdose?

Overdose of Epsolin 100 Tablet may cause jerky movements of the eyes (nystagmus), unclear speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, lightheadedness, fainting, blurred vision, slow and shallow breathing and even coma. Epsolin 100 Tablet overdose can cause very low blood pressure and respiratory problems. As a result of this, the patient can even die.

Who should avoid taking Epsolin 100 Tablet?

You should not take Epsolin 100 Tablet if you have liver disease, especially if you have a history of developing a liver problem due to Epsolin 100 Tablet. Also, patients taking Delavirdine (a medicine used in the treatment of HIV infection) should not take Epsolin 100 Tablet. Epsolin 100 Tablet may reduce the effectiveness of Delavirdine on HIV and the virus may also become resistant to Delavirdine. It is advised that you inform your doctor if you have any existing heart disorder before you receive Epsolin 100 Tablet.

Can I take Epsolin 100 Tablet with ibuprofen?

Epsolin 100 Tablet can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

What are the effects of Epsolin 100 Tablet on children?

The most common side effects related to Epsolin 100 Tablet in children are jerky movements of the eyes (nystagmus) and overgrowth of the gums. In some children, Epsolin 100 Tablet causes problems with thinking or behavior, mood change, slow or clumsy movements, or a loss of energy. Other side effects from high doses include unsteadiness in the feet and hands, sleepiness, and vomiting. These may be avoidable if the dose is increased slowly. These side effects quickly disappear when the dose is reduced.

Does Epsolin 100 Tablet cause weight gain?

Epsolin 100 Tablet has not been reported to cause weight gain. However, weight loss can occur with longer term use of a higher dose of Epsolin 100 Tablet. Please consult your doctor if you experience weight gain after taking Epsolin 100 Tablet.

Does Epsolin 100 Tablet make you sleepy?

Epsolin 100 Tablet can make you feel sleepy (sedation, somnolence, and drowsiness). Please consult your doctor if you feel very sleepy after taking Epsolin 100 Tablet, especially during the first few weeks of treatment or following a dose increase. Talk to your doctor as you may be advised not to drive or use machines until it is established that your ability to perform such activities is not affected.

Does Epsolin 100 Tablet affect birth control?

Epsolin 100 Tablet does affect birth control. Epsolin 100 Tablet can decrease the effect of oral contraceptives (birth control pills) which can make the contraceptive (birth control) effect unreliable. Please talk to your doctor if you are asked to take the two medicines together as you may need to use extra protection for birth control.

Fact Box

Chemical Class

Phenylhydantoins

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Sodium Channel Modulators- Antiepileptic drugs (AEDs)

References

McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 591-93.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 403-405.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1111-116.
Phenytoin. Cedex, France: Famar Orleans; 2018. [Accessed 22 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
Phenytoin. New York, New York: Pfizer; 2009]. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Phenytoin sodium [FDA Label]. Mumbai, India: Wockhardt Limited; 2007. [Accessed 28 Mar. 2023] (online) Available from:
Phenytoin [Prescribing Information]. New York, NY: Parke Davis; 2025. [Accessed 10 Sep 2025] (online) Available from:
Phenytoin [Prescribing Information]. New York, NY: Pfizer Inc.; 2025. [Accessed 05 Nov 2025] (online). Available from:

User feedback

Patients taking Epsolin 100 Tablet

Thrice A Day

100%

What are you using Epsolin Tablet for?

Epilepsy

60%

Others

40%

How much was the improvement?

Average

51%

Excellent

38%

Poor

11%

What were the side-effects while using Epsolin 100 Tablet?

No Side Effect

35%

Rash

15%

Vomiting

10%

Headache

10%

Dizziness

10%

How do you take Epsolin Tablet?

With food

85%

With or without food

15%

Please rate Epsolin 100 Tablet on price

Not Expensive

46%

Average

31%

Expensive

23%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Epsolin 100 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Epsolin 100 Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Epsolin Tablet

Benefits of Epsolin Tablet

Side effects of Epsolin Tablet

How to use Epsolin Tablet

How Epsolin Tablet works

All substitutes for Epsolin 100 Tablet

Celetoin 100 Tablet

Epsod 100mg Tablet

Kiptoin 100mg Tablet

Episol 100mg Tablet

Epilan-P Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ticagrelor (Oral Route)

Ranolazine (Oral Route)

Aripiprazole (Oral Route)

Lorlatinib (Oral Route)

Acenocoumarol (Oral Route)

Frequently asked questions

For how long does Epsolin 100 Tablet stay in your system?

What happens if I stop taking Epsolin 100 Tablet?

What are the symptoms that occur if I take more than the recommended dose of Epsolin 100 Tablet? Can I die from Epsolin 100 Tablet overdose?

Who should avoid taking Epsolin 100 Tablet?

Can I take Epsolin 100 Tablet with ibuprofen?

What are the effects of Epsolin 100 Tablet on children?

Does Epsolin 100 Tablet cause weight gain?

Does Epsolin 100 Tablet make you sleepy?

Does Epsolin 100 Tablet affect birth control?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Epsolin 100 Tablet

What are you using Epsolin Tablet for?

How much was the improvement?

What were the side-effects while using Epsolin 100 Tablet?

How do you take Epsolin Tablet?

Please rate Epsolin 100 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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