Author Details
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
09 Dec 2024 | 01:09 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Enizahex 25 Tablet

Prescription Required
arrow
arrow

Product introduction

Enizahex 25 Tablet is used to treat chorea (which is a movement disorder characterized by involuntary, jerky movements) associated with Huntington's disease. It balances dopamine levels, reducing movements and improving function. This helps it easier for the person to move and function better.

Enizahex 25 Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. This medication must not be stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience neuroleptic malignant syndrome, characterized by fever, muscle rigidity, and altered consciousness or seizures.

Some common side effects of this medicine include nausea, insomnia(difficulty sleeping), anxiety, fatigue, akathisia (restlessness and inability to stay still), and depression. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.

Uses of Enizahex Tablet


Side effects of Enizahex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Enizahex

  • Nausea
  • Insomnia (difficulty in sleeping)
  • Anxiety
  • Fatigue
  • Sleepiness
  • Akathisia (inability to stay still)
  • Depression

How to use Enizahex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Enizahex 25 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Enizahex Tablet works

Enizahex 25 Tablet works by depleting the stores of certain chemical messengers (such as dopamine, serotonin, norepinephrine, and histamine) in the brain that helps in controlling body movements.

Safety advice

Alcohol
UNSAFE
Enizahex 25 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Enizahex 25 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Enizahex 25 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Enizahex 25 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Enizahex 25 Tablet in patients with kidney disease. Please consult your doctor.
However, caution is advised in these patients.
Liver
UNSAFE
Enizahex 25 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Enizahex Tablet?

If you miss a dose of Enizahex 25 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Enizahex 25 Tablet
₹33.0/Tablet
Revocon Tablet
Sun Pharmaceutical Industries Ltd
₹43.3/tablet
31% costlier
Ticstop Tablet
Intas Pharmaceuticals Ltd
₹40.7/tablet
23% costlier
Atrest 25 Tablet
Centaur Pharmaceuticals Pvt Ltd
₹36.6/tablet
11% costlier
Ticfree Tablet
Lyf Healthcare
₹28.4/tablet
14% cheaper
Ticrest 25 Tablet
Chemo Healthcare Pvt Ltd
₹33.4/tablet
1% costlier

Quick tips

  • You have been prescribed Enizahex 25 Tablet to help control movement disorders such as in Huntington’s disease.
  • Be cautious while driving or doing anything that requires concentration as Enizahex 25 Tablet can cause dizziness and sleepiness.
  • Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as the neuroleptic malignant syndrome.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking Enizahex 25 Tablet without talking  to your doctor first as it may cause worsening of symptoms.
  • You have been prescribed Enizahex 25 Tablet to help control movement disorders such as in Huntington’s disease.
  • Be cautious while driving or doing anything that requires concentration as Enizahex 25 Tablet can cause dizziness and sleepiness.
  • Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as the neuroleptic malignant syndrome.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking Enizahex 25 Tablet without talking  to your doctor first as it may cause worsening of symptoms.

Fact Box

Chemical Class
Tetrahydroisoquinoline Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Vesicular Monoamine Transporter 2 (VMAT2) Inhibitors

Interaction with drugs

Taking Enizahex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal. Do not consume Efavirenz with Tetrabenazine.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Voriconazole with Tetrabenazine.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Fluconazole with Tetrabenazine.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Voriconazole with Tetrabenazine.
Concomitant use may affect heart rhythm and may be fatal. Do not consume Tetrabenazine with Bosutinib.

Patient concerns

arrow
The patient ;my uncle, is effected by Huntington's chorea. Please tell me few tips to control the involuntary movements and other problems in it like elevated moods, insomnia , violent behavior etc. Thank you
Dr. Vikas Sharma
Neurology
Needs medicine under medical supervision Deal with him calmly
I grind my teeth in sleep. What should i do?
Dr. Jyoti Kapoor Madan
Psychiatry
Grinding your teeth or bruxism is a sleep related movement disorder.Doctors don't completely understand what causes bruxism. Possible physical or psychological causes may include: Emotions, such as anxiety, stress, anger, frustration or tension Aggressive, competitive or hyperactive personality type Abnormal alignment of upper and lower teeth (malocclusion) Other sleep problems, such as sleep apnea Response to pain from an earache or teething (in children) Stomach acid reflux into the esophagus An uncommon side effect of some psychiatric medications, such as phenothiazines or certain antidepressants A coping strategy or focusing habit Complication resulting from a disorder such as Huntington's disease or Parkinson's diseaseIn case it is causing damage to your teeth , visit a dentist.In case you have headache, facial pain, get a psychiatric evaluation
arrow

FAQs

Can Enizahex 25 Tablet be crushed?

No, Enizahex 25 Tablet should not be crushed, cut, or chewed. It needs to be swallowed as a whole. But if you cannot swallow the whole tablet, tell your doctor who will probably prescribe you another medicine.

Is Enizahex 25 Tablet an antipsychotic?

Enizahex 25 Tablet is not an antipsychotic. It belongs to the vesicular monoamine transporter 2 (VMAT2) inhibitor class of medicines. It works by changing the activity of some natural substances in the brain that affect muscles and nerves.

What is the most important information that I should know about Enizahex 25 Tablet?

Enizahex 25 Tablet may increase the risk of depression or suicidal thoughts in patients with Huntington’s disease. Huntington’s disease is an inherited disease that causes the progressive breakdown of nerve cells in the brain. Therefore, you should not take Enizahex 25 Tablet if you have Huntington’s disease along with depression.

What should I avoid while taking Enizahex 25 Tablet?

Sleepiness is a common side effect of Enizahex 25 Tablet. Therefore, you should avoid driving or operating heavy machinery if you feel sleepy while taking Enizahex 25 Tablet.

Can I stop taking Enizahex 25 Tablet on my own?

No, you should not stop taking Enizahex 25 Tablet suddenly, without talking to your doctor. Sudden discontinuation of the medicine may cause neuroleptic malignant syndrome. This can be characterized by high fever, stiff muscles, confusion, hallucinations, increased sweating, and very fast or uneven heart beat. Hence, to avoid such side effects your doctor will gradually reduce your dose.

Can I take alcohol while on Enizahex 25 Tablet?

You should avoid alcohol since it may add to the sleepiness caused by Enizahex 25 Tablet. Similarly, you should avoid taking medicines which cause sleepiness. If you are not sure about the effects of the medicine, consult with your doctor.

Does Enizahex 25 Tablet affect blood pressure?

Yes, Enizahex 25 Tablet may affect the blood pressure. In some patients it may decrease the levels of blood pressure. Along with that, one may experience dizziness, lightheadedness, and fainting while getting up quickly from a lying position (orthostatic hypotension). To avoid this problem, get out of bed slowly, rest your feet on the floor for a few minutes before standing up.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 480.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1337-38.
  3. Tetrabenazine. Washington, DC: Prestwick Pharmaceutical; 2008. [Accessed 19 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
  5. Tetrabenazine [Product Label]. Centuar Pharma. [Accessed 07 Aug. 2023]. (online) Available from:External Link

Marketer details

Name: Mba Pharmaceuticals Pvt. Ltd.
Address: 2ND FLOOR PLOT NO-68 BLOCK-L DARYAGANJ NEW DELHI-110002 TEL: 011-43545820
Country of origin: India

330
Inclusive of all taxes
MRP340  3% OFF
10.0 tablets in 1 strip
SOLD OUT
Notify me

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.