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Ticstop 25mg Tablet

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SALT COMPOSITION
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Product introduction

Ticstop 25mg Tablet is used to treat chorea (which is a movement disorder characterized by involuntary, jerky movements) associated with Huntington's disease. It reduces movements and improves function. This makes it easier for the person to move and function better.

Ticstop 25mg Tablet should be taken with or without food. However, it is advised to take it at the same time each day, as this helps maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor. This medication must not be stopped suddenly without talking to your doctor, as it may worsen your symptoms.


Some common side effects of this medicine include nausea, insomnia (difficulty sleeping), anxiety, fatigue, akathisia (restlessness and inability to stay still), and depression. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.


Stop taking this medicine immediately if you have a fever, stiff muscles, confusion, or seizures (signs of neuroleptic malignant syndrome). Let your doctor know if you have any medical conditions. Let your doctor also know about all the medications you are taking, as some medicines may interact with Ticstop 25mg Tablet. Pregnant or breastfeeding women should consult their doctor before taking Ticstop 25mg Tablet to ensure safety.


Uses of Ticstop Tablet

Benefits of Ticstop Tablet

In Huntington's disease

Ticstop 25mg Tablet is used to manage involuntary movements (chorea) associated with Huntington’s disease. It helps reduce sudden jerking or twitching motions, improving movement control and supporting better daily functioning and comfort.

Side effects of Ticstop Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ticstop

  • Nausea
  • Insomnia (difficulty in sleeping)
  • Anxiety
  • Fatigue
  • Sleepiness
  • Akathisia (inability to stay still)
  • Depression
  • Agitation

How to use Ticstop Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ticstop 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Ticstop Tablet works

Ticstop 25mg Tablet works by reducing extra dopamine levels in the brain. Dopamine is a chemical that controls movement, and too much of it can cause involuntary, jerky movements seen in Huntington’s disease. Balancing dopamine helps calm these movements, making it easier to control body motions and perform daily activities.

Safety advice

Alcohol
UNSAFE
Ticstop 25mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Ticstop 25mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Ticstop 25mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Ticstop 25mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Ticstop 25mg Tablet in patients with kidney disease. Please consult your doctor.
However, caution is advised in these patients.
Liver
UNSAFE
Ticstop 25mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Ticstop Tablet?

If you miss a dose of Ticstop 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Ticstop 25mg Tablet
₹29.5/Tablet
Revocon Tablet
Sun Pharmaceutical Industries Ltd
₹38.1/tablet
29% costlier
Ticstop Tablet
Intas Pharmaceuticals Ltd
₹39.3/tablet
33% costlier
atRest 25 Tablet
Centaur Pharmaceuticals Pvt Ltd
₹35.4/tablet
20% costlier

Quick tips

  • Be cautious while driving or doing anything that requires concentration, as Ticstop 25mg Tablet can cause dizziness and sleepiness.
  • Inform your doctor if you experience high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as neuroleptic malignant syndrome.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking Ticstop 25mg Tablet without talking to your doctor first, as it may cause worsening of symptoms.

Fact Box

Chemical Class
Tetrahydroisoquinoline Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Vesicular Monoamine Transporter 2 (VMAT2) Inhibitors

Interaction with drugs

Taking Ticstop with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Voriconazole with Tetrabenazine. Concomitant use may affect heart rhythm and may be fatal.
Do not consume Fluconazole with Tetrabenazine. Concomitant use may affect heart rhythm and may be fatal.
Do not consume Voriconazole with Tetrabenazine. Concomitant use may affect heart rhythm and may be fatal.
Do not consume Efavirenz with Tetrabenazine. Concomitant use may affect heart rhythm and may be fatal.
Do not consume Tetrabenazine with Amiodarone. Concomitant use may affect heart rhythm and may be fatal.

Patient concerns

The patient ;my uncle, is effected by Huntington's chorea. Please tell me few tips to control the involuntary movements and other problems in it like elevated moods, insomnia , violent behavior etc. Thank you
Dr. Vikas Sharma
Neurology
Needs medicine under medical supervision Deal with him calmly
I grind my teeth in sleep. What should i do?
Dr. Jyoti Kapoor Madan
Psychiatry
Grinding your teeth or bruxism is a sleep related movement disorder.Doctors don't completely understand what causes bruxism. Possible physical or psychological causes may include: Emotions, such as anxiety, stress, anger, frustration or tension Aggressive, competitive or hyperactive personality type Abnormal alignment of upper and lower teeth (malocclusion) Other sleep problems, such as sleep apnea Response to pain from an earache or teething (in children) Stomach acid reflux into the esophagus An uncommon side effect of some psychiatric medications, such as phenothiazines or certain antidepressants A coping strategy or focusing habit Complication resulting from a disorder such as Huntington's disease or Parkinson's diseaseIn case it is causing damage to your teeth , visit a dentist.In case you have headache, facial pain, get a psychiatric evaluation

FAQs

Is Ticstop 25mg Tablet an antipsychotic?

Ticstop 25mg Tablet is not an antipsychotic. It belongs to the vesicular monoamine transporter 2 (VMAT2) inhibitor class of medicines. It works by changing the activity of some natural substances in the brain that affect muscles and nerves.

What is the most important information that I should know about Ticstop 25mg Tablet?

Ticstop 25mg Tablet may increase the risk of depression or suicidal thoughts in patients with Huntington’s disease. Huntington’s disease is an inherited disease that causes the progressive breakdown of nerve cells in the brain. Therefore, you should not take Ticstop 25mg Tablet if you have Huntington’s disease along with depression.

What should I avoid while taking Ticstop 25mg Tablet?

Sleepiness is a common side effect of Ticstop 25mg Tablet. Therefore, you should avoid driving or operating heavy machinery if you feel sleepy while taking Ticstop 25mg Tablet.

Can I stop taking Ticstop 25mg Tablet on my own?

No, you should not stop taking Ticstop 25mg Tablet suddenly, without talking to your doctor. Sudden discontinuation of the medicine may cause neuroleptic malignant syndrome. This can be characterized by high fever, stiff muscles, confusion, hallucinations, increased sweating, and very fast or uneven heartbeat. Hence, to avoid such side effects, your doctor will gradually reduce your dose.

Can I take alcohol while on Ticstop 25mg Tablet?

You should avoid alcohol since it may add to the sleepiness caused by Ticstop 25mg Tablet. Similarly, you should avoid taking medicines that cause sleepiness. If you are not sure about the effects of the medicine, consult with your doctor.

Does Ticstop 25mg Tablet affect blood pressure?

Yes, Ticstop 25mg Tablet may affect blood pressure. In some patients, it may lower blood pressure. Along with that, one may experience dizziness, lightheadedness, and fainting while getting up quickly from a lying position (orthostatic hypotension). To avoid this problem, get out of bed slowly and rest your feet on the floor for a few minutes before standing up.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 480.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1337-38.
  3. Tetrabenazine [Prescribing Information]. Washington, DC: Prestwick Pharmaceutical; 2008. [Accessed 19 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
  5. Tetrabenazine [Product Label]. Centuar Pharma. [Accessed 07 Aug. 2023]. (online) Available from:External Link
  6. Tetrabenazine [Prescribing Information]. Princeton, NJ: Dr. Reddy’s Laboratories Inc.; 2020. [Accessed 13 Mar. 2025] (online) Available from: External Link

Marketer details

Name: Grievers Remedies
Address: Srinivasa Nagar, Tiruchirappalli, Tamil Nadu
Country of origin: India

295
Inclusive of all taxes
MRP328.13  10% OFF
10.0 tablets in 1 strip
SOLD OUT
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Revocon Tablet
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by Sun Pharmaceutical Industries Ltd
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₹381
₹422.81
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Tetrabenazine (25mg)

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