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EMPRogest -SR 300 Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
EMPRogest -SR 300 Tablet provides progesterone, which is a natural hormone essential for reproductive health. It is used to support pregnancy in female infertility and as part of hormone replacement therapy. It helps regulate the menstrual cycle, prepares the uterus for pregnancy, and balances hormones.
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General Information

The content is shown in English
EMPRogest -SR 300 Tablet image
EMPRogest -SR 300 Tablet image
EMPRogest -SR 300 Tablet image
EMPRogest -SR 300 Tablet image
EMPRogest -SR 300 Tablet image

Product introduction

You should use EMPRogest -SR 300 Tablet as your doctor has advised. Do not use more or less than you have been advised, and do not use it for longer than recommended. You may be asked to continue taking this medicine for a certain period after it is confirmed that you are pregnant.


The most common side effects include headache, stomach cramps, irregular vaginal bleeding or spotting, fluid retention, and nausea. Your doctor may be able to help you reduce or prevent side effects if they bother you or do not go away. Very occasionally, people get a severe allergic reaction that needs urgent medical attention.


Using this medicine may increase your risk of blood clots or breast cancer. EMPRogest -SR 300 Tablet may not suit everybody, and you should tell your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You may be monitored more carefully if you have liver, kidney, or heart problems or have diabetes or asthma.


Let your doctor know your medical history to make sure it is safe for you. Check with your doctor about all other medicines that may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment to check your womb. This medicine can alter your thinking or reactions, and you may feel very tired, so be careful if you drive or need to be alert.

Uses of EMPRogest Tablet SR

Benefits of EMPRogest Tablet SR

Female infertility
EMPRogest -SR 300 Tablet contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. Progesterone helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.
Hormone replacement therapy
Hormone Placement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Side effects of EMPRogest Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of EMPRogest
  • Headache
  • Breast pain
  • Irregular menstrual cycle
  • Abdominal cramp
  • Bloating
  • Nausea
  • Vomiting
  • Hair loss
  • Vaginal yeast infection

How to use EMPRogest Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. EMPRogest -SR 300 Tablet is to be taken on an empty stomach.

How EMPRogest Tablet SR works

EMPRogest -SR 300 Tablet works by preparing the uterus for pregnancy and maintaining a healthy environment for fetal development. It thickens the uterine lining to support implantation and prevents contractions that could lead to early pregnancy loss. Additionally, it helps regulate the menstrual cycle and balances other reproductive hormones. In hormone therapy, it supports overall hormonal stability and helps manage symptoms related to hormonal imbalances.

Quick tips

  • EMPRogest -SR 300 Tablet helps regulate menstrual cycles, treats heavy bleeding, and prevents thickening of the uterus.
  • EMPRogest -SR 300 Tablet is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).
  • EMPRogest -SR 300 Tablet is best taken without food, preferably in the evening or at bedtime.
  • It may cause sleepiness or drowsiness. Do not drive or do anything that requires mental focus until you know how EMPRogest -SR 300 Tablet affects you.
  • It may cause bleeding or spotting between menstrual periods. Let your doctor know if this occurs frequently.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. EMPRogest -SR 300 Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
EMPRogest -SR 300 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
EMPRogest -SR 300 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
EMPRogest -SR 300 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of EMPRogest -SR 300 Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
EMPRogest -SR 300 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking EMPRogest with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Darunavir (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection.
Severe

Mycophenolate mofetil (Oral Route)

Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It is recommended to consult your doctor. Mycophenolate mofetil may reduce the efficacy of Progesterone.
Severe

Perampanel (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection. Perampanel may reduce the efficacy of Progesterone.
Severe

Saquinavir (Oral Route)

It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection.
Severe

Tamoxifen (Oral Route)

Do not consume Tamoxifen with Progesterone if you have or had breast cancer. If essential, consult your doctor.

Frequently asked questions

Yes, taking EMPRogest -SR 300 Tablet may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you. The risk of weight gain is generally less if EMPRogest -SR 300 Tablet is taken with estrogen as a combined pill. But, do not start any hormonal therapy without consulting your doctor.
Progesterone is a very important hormone in fertility. It is a hormone secreted by the ovaries that helps prepare and maintain the uterus for pregnancy. EMPRogest -SR 300 Tablet (a form of progesterone) is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent abortions in some cases. It is also used to prevent premature labor.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Natural Progesterone

References

  1. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
  2. Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
  3. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
  5. Progesterone [Prescribing Information]. St. Petersburg, FL: Catalent Pharma Solutions; 2009. [Accessed 28 Mar. 2023] (online) Available from:
  6. Progesterone [Prescribing Information]. Hyderabad, India: Eugia Pharma Specialities Limited; 2024. [Accessed 04 Mar. 2024] (online) Available from:
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User feedback

Once A Day
69%
Twice A Day
19%
Thrice A Day
12%
Female infertility
40%
Premenstrual syndrome (PMS)
20%
Others
20%
Hormone replacement therapy
20%
Poor
56%
Excellent
33%
Average
11%
Bloating
100%
With food
100%
Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India / Godown A, Gat No. 408 and 410, Vill: Urse, Tal: Maval, Pune-410 506, Maharashtra, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver EMPRogest -SR 300 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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