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Ednil 25mg Tablet CR

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 12 Dec 2025 | 11:03 PM (IST)
Ednil 25mg Tablet CR is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is used to treat major depression and anxiety-related conditions like obsessive-compulsive disorder and panic disorder.
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Ednil 25mg Tablet CR
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General Information

The content is shown in English
Ednil 25mg Tablet CR image
Ednil 25mg Tablet CR image

Product introduction

Ednil 25mg Tablet CR can be taken with or without food. The dose and how often you need to take the medicine will be decided by your doctor. They may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse, or you may suffer from unpleasant withdrawal symptoms such as anxiety, restlessness, palpitations, dizziness, and sleep disturbances.


To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.


Some common side effects of Ednil 25mg Tablet CR include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.


Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Inform your doctor about all the medicines you are taking to ensure safety.

Uses of Ednil Tablet CR

Benefits of Ednil Tablet CR

Treatment of Major Depression
Ednil 25mg Tablet CR helps improve symptoms of major depression by lifting mood, restoring interest in daily activities, and reducing feelings of sadness or hopelessness. It supports better emotional balance over time, which can enhance overall functioning and quality of life.
Treatment of Obsessive-compulsive disorder
In obsessive-compulsive disorder (OCD), Ednil 25mg Tablet CR helps reduce the intensity and frequency of persistent thoughts and the urge to perform repetitive actions. This makes it easier for individuals to manage daily tasks and experience relief from the distress caused by these symptoms.
Treatment of Panic disorder
Ednil 25mg Tablet CR helps people with panic disorder by reducing the number and severity of panic attacks. It also helps ease the constant worry about having another attack. This helps the individuals to feel more in control and comfortable in situations they may have previously avoided.

Side effects of Ednil Tablet CR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ednil
  • Fatigue
  • Dryness in mouth
  • Loss of appetite
  • Increased sweating
  • Nervousness
  • Low sexual desire
  • Insomnia (difficulty in sleeping)
  • Confusion
  • Yawning
  • Nausea
  • Tremors
  • Constipation
  • Erectile dysfunction
  • Delayed ejaculation
  • Decreased libido
  • Dizziness

How to use Ednil Tablet CR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ednil 25mg Tablet CR may be taken with or without food.

How Ednil Tablet CR works

Ednil 25mg Tablet CR is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of panic disorder and obsessive-compulsive disorder.

Quick tips

  • It can take 2-3 weeks for Ednil 25mg Tablet CR to start working.
  • Do not stop treatment suddenly, as this may cause upset stomach, flu-like withdrawal symptoms, and sleep disturbance.
  • If your doctor asks you to stop Ednil 25mg Tablet CR, you should reduce the dose slowly over 4 weeks.
  • Avoid consuming alcohol when taking Ednil 25mg Tablet CR, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Ednil 25mg Tablet CR is very less.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Ednil 25mg Tablet CR
Pregnancy

Pregnancy

UNSAFE
Ednil 25mg Tablet CR is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Ednil 25mg Tablet CR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Ednil 25mg Tablet CR may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Ednil 25mg Tablet CR should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Ednil 25mg Tablet CR should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Ednil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Tapentadol (Nasal Route)

Avoid concurrent use unless your doctor considers it safe.
Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Paroxetine. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Paroxetine. Please consult your doctor.
Life-threatening

Zolmitriptan (Nasal Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Paroxetine. If Tranylcypromine is essential, ensure a gap of at least 1 week after discontinuing Paroxetine. Please consult your doctor.
Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Paroxetine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Paroxetine. Please consult your doctor.

Frequently asked questions

You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.
No, do not stop taking Ednil 25mg Tablet CR abruptly, without consulting your doctor. This is a common problem with Ednil 25mg Tablet CR that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.
Yes, Ednil 25mg Tablet CR use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.
Ednil 25mg Tablet CR should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Ednil 25mg Tablet CR. If your doctor has prescribed Ednil 25mg Tablet CR for your child and you are worried about these side effects, discuss it with your doctor.
No, you should not take Ednil 25mg Tablet CR if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Ednil 25mg Tablet CR. But Ednil 25mg Tablet CR may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.
Yes, you need to be careful while taking this medicine if you are a diabetic. Ednil 25mg Tablet CR may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Selective Seretonin Reuptake Inhibitors (SSRIs)

References

  1. Stahl SM, editor. Paroxetine. In: Stahl's Essential Psychopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 513-19.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1060-69.
  3. Paroxetine [EMC Label]. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2025. [Accessed 25 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
  5. Paroxetine [Product Monograph]. Mississauga, Ontario: GlaxoSmithKline Inc.; 2023. [Accessed 12 Dec. 2025] (online) Available from:
  6. Paroxetine hydrochloride [Product Monograph]. East Windsor, NJ: Aurobindo Pharma Ltd.; 2025. [Accessed 11 Nov. 2025] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Godetia Healthcare
Address: Plot No. 429 Jharmajri, Shivalik Nagar, Baddi, Solan-174103, Himachal Pradesh, India

Vendor Details

Country of origin: India
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