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Dukinase 75000IU Injection

Urokinase (75000IU)

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Dukinase 75000IU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 13 Sep 2026 | 01:05 AM (IST)

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Gurgaon

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General Information

Contains

Urokinase (75000IU)

Marketer

Taj Pharma India Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Dukinase 75000IU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable.

Use of this medicine may cause nausea, vomiting, injection site bleeding, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Dukinase Powder for Injection

Benefits of Dukinase Powder for Injection

Heart attack
Dukinase 75000IU Injection is used in heart attacks to dissolve blood clots that block blood flow to the heart. This helps restore circulation quickly, reduce heart damage, and improve survival outcomes.

Pulmonary embolism
In pulmonary embolism, Dukinase 75000IU Injection helps break down clots in the lungs, improving oxygen flow and relieving symptoms like chest pain and breathlessness. It supports faster recovery and prevents complications.

Side effects of Dukinase Powder for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dukinase

Allergic reaction
Nausea
Vomiting
Injection site bleeding
Decreased blood pressure

How to use Dukinase Powder for Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dukinase Powder for Injection works

Dukinase 75000IU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Quick tips

It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Dukinase 75000IU Injection helps break down blood clots in blood vessels, thereby treating conditions such as heart attack, pulmonary embolism, and stroke.
It should be given as soon as possible (within 12 hours) after the onset of a heart attack.
It is usually given by your nurse or doctor as an infusion (drip) into a vein.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Dukinase 75000IU Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Dukinase 75000IU Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Dukinase 75000IU Injection during breastfeeding is not available. Please consult your doctor.

Driving

NOT RELEVANT

Not relevant, as Dukinase 75000IU Injection is intended for use in hospitalized patients.

Kidney

CAUTION

Dukinase 75000IU Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Dukinase 75000IU Injection is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Dukinase 75000IU Injection is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Dukinase with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cilostazol (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).

Severe

Apixaban (Oral Route)

Do not consume Apixaban with Urokinase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Urokinase may increase the effect of Apixaban.

Severe

Streptokinase (Injection Route)

Do not consume Streptokinase with Urokinase. If Streptokinase is essential, ensure a gap of At least 5 days between taking Streptokinase and Urokinase. Please consult your doctor. Urokinase may reduce the efficacy of Streptokinase.

Moderate

Ticagrelor (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Rivaroxaban (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

Can the use of Dukinase 75000IU Injection increase the risk of bleeding?

Yes, Dukinase 75000IU Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

What medicines should I avoid while taking Dukinase 75000IU Injection?

Dukinase 75000IU Injection can interact with several medicines. Do not take any medicine without talking to your doctor.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

CARDIAC

Action Class

First-Generation Thrombolytics

Related lab tests

Platelet Count

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1414-5.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Taj Pharma India Ltd
Address: first floor, 15-6-108 afzal gunj, hyderabad, telangana 500012

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Dukinase 75000IU Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Cardiac

Fibrinolytics

Dukinase 75000IU Injection

Dukinase 75000IU Injection

Payment, Returns & Expiry

Cash on delivery available

7 day free return

Product expires after Dec, 2026

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Dukinase Powder for Injection

Benefits of Dukinase Powder for Injection

Side effects of Dukinase Powder for Injection

How to use Dukinase Powder for Injection

How Dukinase Powder for Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cilostazol (Oral Route)

Apixaban (Oral Route)

Streptokinase (Injection Route)

Ticagrelor (Oral Route)

Rivaroxaban (Oral Route)

Frequently asked questions

Can the use of Dukinase 75000IU Injection increase the risk of bleeding?

What medicines should I avoid while taking Dukinase 75000IU Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Platelet Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests