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Disonate 200mg Tablet

Etidronate (200mg)
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Disonate 200mg Tablet is used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or use of steroids. Using this medicine can reduce your risk of breaking bones.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 05 Jan 2026 | 05:03 PM (IST)
₹199 MRP ₹222.6611% off 
 
 
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General Information

The content is shown in English
Disonate 200mg Tablet image
Disonate 200mg Tablet image

Product introduction

Disonate 200mg Tablet is best taken without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. Do not stop taking it until you have finished, even when you feel better. It may take several days to get the full benefit of this drug. Disonate 200mg Tablet is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.

The most common side effects include headache, musculoskeletal (bone, muscle or joint) pain, indigestion, heartburn, and diarrhea. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Disonate 200mg Tablet can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills), or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away.

You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also, let your doctor know what other drugs you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.

Uses of Disonate Tablet

Benefits of Disonate Tablet

Osteoporosis
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause or who are taking steroids. This condition can be treated with bone-strengthening medicines. Disonate 200mg Tablet slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. You can also help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D, and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Side effects of Disonate Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Disonate
  • Headache
  • Musculoskeletal (bone, muscle or joint) pain
  • Heartburn
  • Diarrhea
  • Indigestion

How to use Disonate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Disonate 200mg Tablet may be taken with or without food.

How Disonate Tablet works

Disonate 200mg Tablet is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.

All substitutes for Disonate 200mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Your doctor has prescribed Disonate 200mg Tablet to make your bones stronger and lower the risk of fractures.
  • Take it in the morning at least 30 minutes before eating or drinking anything.
  • Maintain an upright posture for 30 minutes after taking the medication so the medicine does not irritate your food pipe.
  • It may cause the amount of calcium in your blood to fall. Take calcium-rich food in your diet and have regular blood tests to monitor the level of calcium in your blood.
  • It is important to look after your mouth and teeth while you are taking this medicine. Have regular dental check-ups and inform your dentist about taking Disonate 200mg Tablet.
  • Your doctor has prescribed Disonate 200mg Tablet to make your bones stronger and lower the risk of fractures.
  • Take it in the morning at least 30 minutes before eating or drinking anything.
  • Maintain an upright posture for 30 minutes after taking the medication so the medicine does not irritate your food pipe.
  • It may cause the amount of calcium in your blood to fall. Take calcium-rich food in your diet and have regular blood tests to monitor the level of calcium in your blood.
  • It is important to look after your mouth and teeth while you are taking this medicine. Have regular dental check-ups and inform your dentist about taking Disonate 200mg Tablet.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Disonate 200mg Tablet does not usually cause any harmful side effects.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Disonate 200mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Disonate 200mg Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
If you are taking Disonate 200mg Tablet during breastfeeding, monitor baby's blood calcium levels during the first two months.
Driving

Driving

SAFE
Disonate 200mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Disonate 200mg Tablet in patients with kidney disease. Please consult your doctor.
However, regular monitoring of kidney function tests is advised while the patient is taking this medicine. Use of Disonate 200mg Tablet is not recommended in severe kidney disease patients.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Disonate 200mg Tablet in patients with liver disease.

Interaction with drugs

Taking Disonate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Iron (Oral Route)

Take Etidronate on an empty stomach at least 2 hours after taking Iron.
Moderate

Amikacin (Injection Route)

Your doctor may monitor your calcium and magnesium levels along with your overall treatment and adjust the doses as per the observations.
Moderate

Calcium (Oral Route)

Take Etidronate on an empty stomach at least 2 hours after taking Calcium.
Moderate

Gentamicin (Injection Route)

Your doctor may monitor your calcium and magnesium levels along with your overall treatment and adjust the doses as per the observations.
Moderate

Kanamycin (Injection Route)

Your doctor may monitor your calcium and magnesium levels along with your overall treatment and adjust the doses as per the observations.

Frequently asked questions

It should be taken in the morning after getting up on an empty stomach with a full glass of water. Do not lie down and stay fully upright for at least 30 minutes after swallowing the medicine. Avoid taking any food or medication for the next 30 mins after taking this medicine. Take this medicine only after consulting the doctor and follow the instructions advised.
If you forget a dose of Disonate 200mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Disonate 200mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
No, one should not lie down. This is because there is a possibility that the medication might come back up into the esophagus (food pipe) and even damage the esophagus. Staying upright will help the medicine to settle down quickly in your stomach and prevent side effects like heartburn and pain.
Yes, Disonate 200mg Tablet can cause hair loss, but this is not a common side effect. If you experience hair loss while taking this medication immediately report to your doctor and follow the advice given.
Disonate 200mg Tablet should be avoided during pregnancy. There is a lack of data regarding the use of Disonate 200mg Tablet in pregnant women. You should consult your doctor if you are pregnant or planning to get pregnant before taking this medication.
Disonate 200mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Disonate 200mg Tablet too early, the symptoms may return or worsen.

Fact Box

Chemical Class

Bisphosphonates

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Bone Resorption Inhibitors- Bisphosphonates

Related lab tests

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 517.
  2. Etidronate. North Norwich, New York: Norwich Pharmaceuticals, Inc.; 2009. [Accessed 02 Apr. 2019] (online) Available from:
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090. || 136, New Ashirwad Ind. Est. No.5, Ram Mandir Road, Goregaon (W), Mumbai - 400 104, India

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Country of origin: India
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