Diafer Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 30 Mar 2026 | 02:16 PM (IST)

Diafer Tablet is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevents serious complications of diabetes. It is also used to treat a menstruation-related disorder known as polycystic ovary syndrome (PCOS) in women.

Genuine

Authenticity Assured

Prescription

required

NPPA Regulated

Show Details

₹16.5 MRP ₹18.3210% off

Diafer Tablet is currently sold out

Same composition alternative:

Okamet 500 Tablet

₹18.6~~₹26.33~~

44% cheaper alternative available from Cipla

Sold out

Diafer Tablet

strip of 10 tablets

₹16.5

~~₹18.32~~

Same composition

Okamet 500 Tablet

strip of 20 tablets

Metformin (500mg)

by Cipla Ltd

Get in 30 mins

₹18.6

₹0.79 per tablet

₹15.8

order for

₹1200

Save more with additional offers

Assured cashback up to ₹300 using Paytm UPI*

10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Save more with additional offers

Assured cashback up to ₹300 using Paytm UPI*

10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Metformin (500mg)

Marketer

East West Pharma

Storage

Store below 25°C

The content is shown in English

Product introduction

Diafer Tablet is best taken with food to avoid nausea and abdominal pain. You should take it regularly, at the same time each day, to get the most benefit. You should not stop taking this medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine.

The most common side effects of this medicine include diarrhea, nausea, vomiting, abdominal discomfort, headache, and loss of appetite. Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines or alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it.

Before taking this medicine, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function before starting treatment with it. Avoid excessive alcohol intake while taking it, as this may increase the risk of developing some side effects.

Uses of Diafer Tablet

Benefits of Diafer Tablet

Treatment of Type 2 diabetes mellitus
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level, you will reduce the risk of getting any of the serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking Diafer Tablet regularly, along with proper diet and exercise, will help you live a normal, healthy life.

Treatment of Polycystic ovarian syndrome (PCOS)
Diafer Tablet helps manage PCOS by improving insulin sensitivity, lowering insulin levels, and reducing androgen production, which aids in regulating menstrual cycles, improving ovulation, and reducing symptoms like acne and excess hair growth. It also supports weight management.

Side effects of Diafer Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Diafer

Diarrhea
Headache
Vomiting
Nausea
Abdominal discomfort

How to use Diafer Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diafer Tablet should be taken with or after food.

How Diafer Tablet works

Diafer Tablet is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin. In PCOS, Diafer Tablet improves insulin sensitivity, lowering insulin and androgen levels and restoring ovulation and menstrual regularity. Reducing insulin resistance helps manage acne, excess hair growth, weight, and diabetes risk, making it effective for both metabolic and reproductive symptoms.

All substitutes for Diafer Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

The chances of weight gain and low blood sugar are lower with this medicine as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines or alcohol, or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain, as Diafer Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Prolonged use of Diafer Tablet may lead to vitamin B12 deficiency, which may lead to anemia, causing fatigue, pale skin, shortness of breath, or headache. Notify your doctor if you experience any of these, as you may require supplements.
Your doctor will monitor your blood sugar levels and kidney function regularly while you are taking this medication.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Diafer Tablet

Pregnancy

SAFE IF PRESCRIBED

Diafer Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Diafer Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

SAFE

Diafer Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Diafer Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Diafer Tablet is, however, not recommended in patients with severe kidney disease.

Liver

UNSAFE

Diafer Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Diafer with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.

Moderate

Acetazolamide (Oral Route)

If concurrent use is essential, watch out for symptoms such as weakness, nausea, vomiting, abdominal pain, irregular heartbeat, fatigue or loss of appetite and consult your doctor if you experience them. They may monitor your kidney function frequently.

Moderate

Amisulpride (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Metformin.

Moderate

Amisulpride (Injection Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Metformin.

Moderate

Aripiprazole (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Aripiprazole may reduce the efficacy of Metformin.

Frequently asked questions

What does Diafer Tablet do exactly?

Diafer Tablet works in PCOS by making the body more sensitive to insulin. In PCOS, the body often doesn’t respond well to insulin, leading to high insulin levels. This can cause the ovaries to produce excess male hormones, leading to irregular periods, acne, and unwanted hair growth. Diafer Tablet lowers insulin levels, helping to balance hormones, regulate periods, and reduce these symptoms.<br><br>For type 2 diabetes, Diafer Tablet helps control blood sugar levels in three ways: it reduces the amount of sugar the liver makes, helps the body use insulin more effectively, and lowers sugar absorption from food. This helps prevent blood sugar spikes and manage diabetes better.

What are the benefits of taking Diafer Tablet?

Diafer Tablet benefits polycystic ovary syndrome (PCOS) by improving how the body responds to insulin, lowering insulin levels, and reducing excess male hormone production. This helps restore hormonal balance, regulate menstrual cycles, and relieve symptoms like acne and excess hair growth. It also supports weight management and lowers the risk of type 2 diabetes. Additionally, Diafer Tablet controls blood sugar by enhancing the body's insulin response, reducing sugar production in the liver, and limiting sugar absorption from the intestines. Unlike some other antidiabetic medicines, it rarely causes low blood sugar when taken alone.

Does Diafer Tablet cause weight loss?

Yes, Diafer Tablet has been shown to cause mild weight loss in some people. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

Can Diafer Tablet make you sleepy?

Diafer Tablet usually does not cause sleepiness and is well tolerated. However, the use of Diafer Tablet may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Diafer Tablet.

How to take Diafer Tablet?

Take Diafer Tablet with or after a meal. Do not crush or chew the Diafer Tablet, and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and the other in the evening with dinner. In the case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Diafer Tablet with meals will reduce digestive problems like indigestion, nausea, vomiting, diarrhea, stomachache, and loss of appetite.

Fact Box

Chemical Class

Biguanide derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Biguanides

Related lab tests

Follicle Stimulating Hormone

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

Luteinising Hormone

Thyroid Stimulating Hormone

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1258-60.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 741-42.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 873-75.
Metformin hydrochloride [FDA Label]. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 12 Mar. 2019] (online) Available from:
Metformin hydrochloride oral solution [FDA Label]. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 12 Mar. 2019] (online) Available from:
Metformin [EMC Label]. Middlesex, UK: Merck Serono Ltd.; 2020. [Accessed 27 Sep. 2021]. (online) Available from:
Metformin [FDA Label]. Princeton, NJ: Bristol-Myers Squibb Company; 2017. [Accessed 26 Sept. 2021] (online) Available from:
Metformin [FDA Label]. Hyderabad: Granules India Limited; 2016. [Accessed 27 Sept. 2021]. (online) Available from:
National Health Service. Pregnancy, breastfeeding and fertility while taking metformin. [Last Reviewed: 24 Mar. 2022]. [Accessed 11 Jul. 2023]. (online) Available from:
Metformin [Summary of Product Characteristics]. Abuja, Nigeria: Bell Bag Pharmaceuticals; 2025. [Accessed 11 Jul. 2023] (online) Available from:

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: East West Pharma
Address: H.O. No. 196, Raipur Ind. Area, Bhagwanpur, Roorkee, Haridwar, Uttarakhand-247661, INDIA

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Diafer Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Diafer Tablet

Benefits of Diafer Tablet

Side effects of Diafer Tablet

How to use Diafer Tablet

How Diafer Tablet works

All substitutes for Diafer Tablet

Okamet 500 Tablet

Biciphage 500 Tablet

Metform 500mg Tablet

Glyciphage Tablet

Glycomet Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Disopyramide (Oral Route)

Acetazolamide (Oral Route)

Amisulpride (Oral Route)

Amisulpride (Injection Route)

Aripiprazole (Oral Route)

Frequently asked questions

What does Diafer Tablet do exactly?

What are the benefits of taking Diafer Tablet?

Does Diafer Tablet cause weight loss?

Can Diafer Tablet make you sleepy?

How to take Diafer Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Follicle Stimulating Hormone

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

Luteinising Hormone

Thyroid Stimulating Hormone

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests