Author Details
Written By
BDS
Reviewed By
MD Pharmacology, MBBS
Last updated
04 Dec 2024 | 11:15 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Dexdine 100mcg Injection

Prescription Required

Product introduction

Dexdine 100mcg Injection is a prescription medicine used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings. It may also be used for awake sedation during diagnostic and surgical procedures.

Dexdine 100mcg Injection is given as an infusion (drip) into a vein under the supervision of a healthcare professional. It is important to inform your doctor if you are suffering from any medical conditions like slow heart rate, low blood pressure, neurological disorder, severe liver problems, or have ever developed a serious fever after some medicines, especially after taking anesthesia. Your doctor will monitor the cardiac and respiratory state after providing this injection.

Common side effects of this medicine include dryness in the mouth, decreased blood pressure, and slow heart rate. Consult your doctor if these side effects do not improve with time or worsen. They may be able to suggest ways to prevent or reduce the side effects.

Uses of Dexdine Injection

  • Sedative

Side effects of Dexdine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dexdine

  • Dryness in mouth
  • Decreased blood pressure
  • Slow heart rate

How to use Dexdine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dexdine Injection works

Dexdine 100mcg Injection works by modulating the action of certain chemical messengers in the brain that relieves pain and induces sleep.

Safety advice

Alcohol
UNSAFE
Dexdine 100mcg Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Dexdine 100mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Dexdine 100mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
NOT RELEVANT
Not relevant, as Dexdine 100mcg Injection is intended for use in hospitalised patients.
Kidney
SAFE IF PRESCRIBED
Dexdine 100mcg Injection is safe to use in patients with kidney disease. No dose adjustment of Dexdine 100mcg Injection is recommended.
Liver
CAUTION
Dexdine 100mcg Injection should be used with caution in patients with liver disease. Dose adjustment of Dexdine 100mcg Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Dexdine 100mcg Injection
₹539/Injection
Dexem 100mcg Injection
Themis Medicare Ltd
₹690/injection
25% costlier
Dexmedine Injection
Samarth Life Sciences Pvt Ltd
₹241.56/injection
56% cheaper
Dexem 100mcg Injection
Themis Medicare Ltd
₹423.5/injection
23% cheaper
Dexmedine 100mcg Injection
Samarth Life Sciences Pvt Ltd
₹380/injection
31% cheaper
Alphadex 100mcg Injection
Fusion Healthcare Pvt Ltd
₹330/injection
40% cheaper

Quick tips

  • Dexdine 100mcg Injection is given as an infusion into the veins by healthcare professionals only.
  • Your doctor will closely monitor your heart rate, blood pressure, breathing rate and oxygen level during the treatment.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Imidazole Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Centrally Acting Alpha-2 Agonist- Sedative Agents

Interaction with drugs

Taking Dexdine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Although the likelihood is low, concurrent use may cause a slow heart rate. Monitor your heart rate regularly and talk to your doctor if you notice persistently low heart rate.
Although the likelihood is low, concurrent use may cause a slow heart rate. Monitor your heart rate regularly and talk to your doctor if you notice persistently low heart rate.

Patient concerns

arrow
For atleast 1 year she was on anti depressant and mild sedative in allopathic .now she is pregnant ,suggest me some medicine that can replace once and for all that allopathic medicines.
Dr. Deepak Kumar Soni
Ayurveda
http://www.1mgayush.com/Anxiety-and-Stress/products/BRAMHI-XT,-500MG/StandardClick this link & order the medicine for your problem
1) not getting sleep 2) in the afternoons drouzy, 3) too mucgh irritation
Dr. Ambrish Dharmadhikari
Psychiatry
It seems your sleep wake cycle is disturbed. You can try some home remedy like drinking warm milk, use of sedative spices (nutmeg) available at home. It this doesn't help then you can take help from psychiatrist for medications. - Dr. Ambrish Dharmadhikari Consultant Psychiatrist, Mumbai
arrow

FAQs

What is Dexdine 100mcg Injection used for?

Dexdine 100mcg Injection is used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings (i.e. in initially intubated and mechanically ventilated patients or non-intubated patients prior to and/or during surgical and other procedures).

Is Dexdine 100mcg Injection a controlled substance?

Dexdine 100mcg Injection is a sedative that belongs to a class of drugs called centrally active selective 2A agonists.It is not a controlled drug/substance

Is Dexdine 100mcg Injection approved by FDA?

Yes, Dexdine 100mcg Injection approved by FDA

Does Dexdine 100mcg Injection cause amnesia?

Dexdine 100mcg Injection is given as an infusion (drip) into veins. It may cause pain at the injection site and low heart rate (bradycardia). It does not cause amnesia.

How does Dexdine 100mcg Injection work?

Dexdine 100mcg Injection activates the central 2A receptors which causes sedation and analgesia.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Dextromethorphan. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 181-83.
  2. Patel PM, Patel HH, Roth DM. General Anesthetics and Therapeutic Gases. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 548-49.
  3. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 140, 145.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 381-82.
  5. Dexmedetomidine hydrochloride. Lake Forest, Illinois: Hospira, Inc.; 1999 [revised Jun. 2013]. [Accessed 12 Feb. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dexmedetomidine. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Country of origin: India

539
Inclusive of all taxes
MRP550  2% OFF
2.0 ml in 1 vial
SOLD OUT
Notify me

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.