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Dexem 100mcg Injection

Dexmedetomidine (100mcg)

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Dexem 100mcg Injection is a prescription medicine used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings. It may also be used for awake sedation during diagnostic and surgical procedures.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 22 Sep 2025 | 06:07 PM (IST)

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2 ml Injection

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General Information

Contains

Dexmedetomidine (100mcg)

Marketer

Themis Medicare Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Dexem 100mcg Injection is given as an infusion (drip) into a vein under the supervision of a healthcare professional. It is important to inform your doctor if you are suffering from any medical conditions like slow heart rate, low blood pressure, neurological disorder, severe liver problems, or have ever developed a serious fever after some medicines, especially after taking anesthesia. Your doctor will monitor the cardiac and respiratory state after providing this injection.

Common side effects of this medicine include dryness in the mouth, decreased blood pressure, and slow heart rate. Consult your doctor if these side effects do not improve with time or worsen. They may be able to suggest ways to prevent or reduce the side effects.

Uses of Dexem Injection

Sedative

Benefits of Dexem Injection

Sedative
Dexem 100mcg Injection is used to help calm and sedate patients, especially in intensive care or during surgical procedures. It provides sedation without causing significant breathing problems, making it safer in controlled settings. It also helps reduce anxiety and discomfort while ensuring the patient remains relaxed.

Side effects of Dexem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dexem

Slow heart rate
Dryness in mouth
Decreased blood pressure

How to use Dexem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dexem Injection works

Dexem 100mcg Injection works by modulating the action of certain chemical messengers in the brain that relieves pain and induces sleep.

All substitutes for Dexem 100mcg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Dexem 100mcg Injection is given as an infusion into the veins by healthcare professionals only.
Your doctor will closely monitor your heart rate, blood pressure, breathing rate and oxygen level during the treatment.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

UNSAFE

Dexem 100mcg Injection may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Dexem 100mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Dexem 100mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

NOT RELEVANT

Not relevant, as Dexem 100mcg Injection is intended for use in hospitalised patients.

Kidney

SAFE IF PRESCRIBED

Dexem 100mcg Injection is safe to use in patients with kidney disease. No dose adjustment of Dexem 100mcg Injection is recommended.

Liver

CAUTION

Dexem 100mcg Injection should be used with caution in patients with liver disease. Dose adjustment of Dexem 100mcg Injection may be needed. Please consult your doctor.

Interaction with drugs

Taking Dexem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Mild

Digoxin (Oral Route)

Monitor your heart rate regularly and talk to your doctor if you notice persistently low heart rate.

Mild

Digoxin (Injection Route)

Monitor your heart rate regularly and talk to your doctor if you notice persistently low heart rate.

Frequently asked questions

What is Dexem 100mcg Injection used for?

Dexem 100mcg Injection is used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings (i.e. in initially intubated and mechanically ventilated patients or non-intubated patients prior to and/or during surgical and other procedures).

Is Dexem 100mcg Injection a controlled substance?

Dexem 100mcg Injection is a sedative that belongs to a class of drugs called centrally active selective 2A agonists.It is not a controlled drug/substance

Is Dexem 100mcg Injection approved by FDA?

Yes, Dexem 100mcg Injection approved by FDA

Does Dexem 100mcg Injection cause amnesia?

Dexem 100mcg Injection is given as an infusion (drip) into veins. It may cause pain at the injection site and low heart rate (bradycardia). It does not cause amnesia.

How does Dexem 100mcg Injection work?

Dexem 100mcg Injection activates the central 2A receptors which causes sedation and analgesia.

Fact Box

Chemical Class

Imidazole Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Centrally Acting Alpha-2 Agonist- Sedative Agents

References

Stahl SM, editor. Dextromethorphan. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 181-83.
Patel PM, Patel HH, Roth DM. General Anesthetics and Therapeutic Gases. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 548-49.
Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 140, 145.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 381-82.
Dexmedetomidine hydrochloride. Lake Forest, Illinois: Hospira, Inc.; 1999 [revised Jun. 2013]. [Accessed 12 Feb. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dexmedetomidine. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:

User feedback

What are you using Dexem Injection for?

Others

50%

Sedative

50%

How much was the improvement?

Excellent

67%

Average

33%

What were the side-effects while using Dexem 100mcg Injection?

Decreased blood pressure

100%

How do you take Dexem Injection?

Empty stomach

100%

Please rate Dexem 100mcg Injection on price

Expensive

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Themis Medicare Ltd
Address: 11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Dexem 100mcg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Dexem 100mcg Injection

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Expiry after

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Dexem Injection

Benefits of Dexem Injection

Side effects of Dexem Injection

How to use Dexem Injection

How Dexem Injection works

All substitutes for Dexem 100mcg Injection

Dextomid 100mcg Injection

Dexmedine 100mcg Injection

Dexmedine Injection

Dexit 100mcg Injection

Xamex 100 Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Digoxin (Oral Route)

Digoxin (Injection Route)

Frequently asked questions

What is Dexem 100mcg Injection used for?

Is Dexem 100mcg Injection a controlled substance?

Is Dexem 100mcg Injection approved by FDA?

Does Dexem 100mcg Injection cause amnesia?

How does Dexem 100mcg Injection work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

What are you using Dexem Injection for?

How much was the improvement?

What were the side-effects while using Dexem 100mcg Injection?

How do you take Dexem Injection?

Please rate Dexem 100mcg Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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