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Dexmedine Injection


Overview

Introduction

Dexmedine Injection is a prescription medicine used to provide sedation (a state of calm, drowsiness, or sleep) for adult patients in intensive care settings. It may also be used for awake sedation during diagnostic and surgical procedures.

Dexmedine Injection is given as an infusion (drip) into a vein under the supervision of a healthcare professional. It is important to inform your doctor if you are suffering from any medical conditions like slow heart rate, low blood pressure, neurological disorder, severe liver problems, or have ever developed a serious fever after some medicines, especially after taking anesthesia. Your doctor will monitor the cardiac and respiratory state after providing this injection.

It may cause dryness in mouth, decreased blood pressure and slow heart rate as side effects of this medicine. Please consult your doctor if these side effects do not improve with time or worsen.

Uses of Dexmedine Injection

  • Sedative

Side effects of Dexmedine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dexmedine

  • Decreased blood pressure
  • Dryness in mouth

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Decreased blood pressure
    Get up slowly from a sitting or lying position. Try to avoid changing positions suddenly even in general. Try crossing your legs when you are sitting and wearing compression stockings. Drink plenty of water and try eating smaller, more frequent meals. Although salt is not good for everyone (and bad for some people), if you have low blood pressure increasing your intake of salt (sodium) can raise your blood pressure. Cut down the amount of alcohol you drink. If your blood pressure becomes very low, you should talk to your doctor.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.

How to use Dexmedine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dexmedine Injection works

Dexmedine Injection works by modulating the action of certain chemical messengers in the brain that relieves pain and induces sleep.

Safety Advice

Alcohol
UNSAFE
Dexmedine Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Dexmedine Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Dexmedine Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
NOT RELEVANT
Not relevant, as Dexmedine Injection is intended for use in hospitalised patients.
Kidney
SAFE IF PRESCRIBED
Dexmedine Injection is safe to use in patients with kidney disease. No dose adjustment of Dexmedine Injection is recommended.
Liver
CAUTION
Dexmedine Injection should be used with caution in patients with liver disease. Dose adjustment of Dexmedine Injection may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Dexmedine Injection
₹200.0/ml of Injection
Alphadex 100mcg Injection
Fusion Healthcare Pvt Ltd
₹330/ml of Injection
65% costlier
Dexem 100mcg Injection
Themis Medicare Ltd
₹345/ml of Injection
72% costlier
Dexmedine 100mcg Injection
Samarth Life Sciences Pvt Ltd
₹380/ml of Injection
90% costlier
Dextomid 100mcg Injection
Neon Laboratories Ltd
₹390/ml of Injection
95% costlier
Dexem 100mcg Injection
Themis Medicare Ltd
₹423.5/ml of Injection
112% costlier

Quick Tips

  • Dexmedine Injection is given as an infusion into the veins by healthcare professionals only.
  • Your doctor will closely monitor your heart rate, blood pressure, breathing rate and oxygen level during the treatment.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Imidazole Derivative
Habit Forming
No

Patient Concerns

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Do you have any questions related to Dexmedine Injection ?

FAQs

Q. What is Dexmedine/Dexmedine HCL used for?

Dexmedine. Dexmedine HCL is used to provide sedation (a state of calm, drowsiness or sleep) for adult patients in intensive care settings (i.e. in initially intubated and mechanically ventilated patients or non-intubated patients prior to and/or during surgical and other procedures)

Q. What class is Dexmedine/ is Dexmedine a controlled substance?

It is a sedative that belongs toclassof drugs called centrally active selective 2A agonists.It is not a controlled drug/substance

Q. Is Dexmedine approved by FDA?

Yes, Dexmedine approved by FDA

Q. Does Dexmedine cause amnesia/pain on inje ction/bradycardia?

Dexmedine is given as an infusion (drip) into veins. It may cause pain at injection site and low heart rate (bradycardia). It does not cause amnesia

Q. How does Dexmedine work?

Dexmedine activates the central 2A receptors which causes sedation and analgesia.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Dextromethorphan. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 181-83.
  2. Patel PM, Patel HH, Roth DM. General Anesthetics and Therapeutic Gases. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 548-49.
  3. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 140, 145.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 381-82.
  5. Dexmedetomidine hydrochloride. Lake Forest, Illinois: Hospira, Inc.; 1999 [revised Jun. 2013]. [Accessed 12 Feb. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dexmedetomidine. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Country of Origin: India
A licensed vendor partner from your nearest location will deliver Dexmedine Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹170
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0.5 ml in 1 vial
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