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Dr. Swati Mishra
BDS
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MD Pharmacology, MBBS
Last updated
15 Dec 2024 | 01:01 AM (IST)

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Depravan ER 75 Tablet Tablet PR

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Product introduction

Depravan ER 75 Tablet Tablet PR is used in the treatment of depression and anxiety disorder. It alters the chemicals in the brain that cause symptoms of anxiety such as irritability, restlessness, lack of concentration, fatigue, sweating, increased heart rate, and unwanted or racing thoughts.

Depravan ER 75 Tablet Tablet PR should be taken with food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include nausea, vomiting, insomnia (difficulty in sleeping), decreased appetite, anxiety, constipation, increased sweating, and sexual dysfunction. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.

Before taking Depravan ER 75 Tablet Tablet PR, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.

Side effects of Depravan Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Depravan

  • Nausea
  • Vomiting
  • Dizziness
  • Insomnia (difficulty in sleeping)
  • Decreased appetite
  • Anxiety
  • Constipation
  • Increased sweating
  • Sexual dysfunction

How to use Depravan Tablet PR

Use it as advised by your doctor or check the label for directions before use. Depravan ER 75 Tablet Tablet PR is to be taken with food.

How Depravan Tablet PR works

Depravan ER 75 Tablet Tablet PR works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Depravan ER 75 Tablet Tablet PR.
Pregnancy
CONSULT YOUR DOCTOR
Depravan ER 75 Tablet Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Depravan ER 75 Tablet Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for excessive sleepiness and adequate weight gain.
Driving
UNSAFE
Depravan ER 75 Tablet Tablet PR may cause side effects which could affect your ability to drive.
As side effects of Depravan ER 75 Tablet Tablet PR are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
Kidney
CAUTION
Depravan ER 75 Tablet Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Depravan ER 75 Tablet Tablet PR may be needed. Please consult your doctor.
Liver
CAUTION
Depravan ER 75 Tablet Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Depravan ER 75 Tablet Tablet PR may be needed. Please consult your doctor.

What if you forget to take Depravan Tablet PR?

If you miss a dose of Depravan ER 75 Tablet Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Depravan ER 75 Tablet Tablet PR
₹10.8/Tablet PR
Ventab XL 75 Tablet PR
Intas Pharmaceuticals Ltd
₹14.1/tablet pr
31% costlier
Ventin XR-75 Tablet
D D Pharmaceuticals
₹8.56/tablet pr
21% cheaper
Venfax 75mg Tablet PR
Micro Labs Ltd
₹3.86/tablet pr
64% cheaper
Venjoy XR 75 Tablet
Manas Pharma MFG
₹5.65/tablet pr
48% cheaper
Venlayork 75 Tablet PR
Mediverge Healthcare Pvt Ltd
₹10.8/tablet pr
same price

Quick tips

  • Depravan ER 75 Tablet Tablet PR helps in treating depression and anxiety.
  • It may take 2 to 4 weeks for Depravan ER 75 Tablet Tablet PR to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Depravan ER 75 Tablet Tablet PR as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.
  • Depravan ER 75 Tablet Tablet PR helps in treating depression and anxiety.
  • It may also  be used to treat nerve pain from diabetes and some other forms of chronic pain.
  • It may take 2 to 4 weeks for Depravan ER 75 Tablet Tablet PR to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Depravan ER 75 Tablet Tablet PR as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause an increase in blood pressure, especially during the first month of treatment. Monitor your blood pressure regularly.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Anisole Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)

Interaction with drugs

Taking Depravan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moclobemide (Oral Route) Life-threatening
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Selegiline (Oral Route) Life-threatening
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Domperidone (Oral Route) Life-threatening
Concomitant use may affect heart rhythm and can be fatal. Do not consume Venlafaxine with Domperidone.
Tapentadol (Nasal Route) Life-threatening
Concurrent use may cause fatal rise in blood serotonin levels. Avoid concurrent use unless your doctor considers it safe.
Zolmitriptan (Oral Route) Life-threatening
Concurrent use may cause serotonin syndrome. If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult... More
View all drug interactions

Patient concerns

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Mental Depression , Anxiety disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
MORE
What are possible physical symptoms of anxiety disorder and depression.
Dr. Subrata Naskar
Psychiatry
Hi PATIENT me clear that for you. Depression is usually associated with a lot of physical symptoms like increased fatigue, decreased amount of sleep or interrupted sleep, loss of appetite usually cause more than 5% body weight loss, loss of libido. But its effect is mainly psychological whivh causes persist low mood, inability to enjoy pleasurable activities, low self esteem, bleak view of the future, guilty feeling etc. These symptoms have to be present persistently for 2 weeks to be called depression. On the other hand, anxiety has two main components, worry and fear. The common physical complaints are extreme sweating, butterfly like feeling in stomach, fidgetiness, increased frequency of urination. If associated with panic attacks, there is often palpitation, respiratory distress, dryness of throat, a sense of doom. Anxiety disorders are of various types and each have varied specific set of symptoms, but these are usually in common.
MORE
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FAQs

Can Depravan ER 75 Tablet Tablet PR cause sedation?

Yes. Depravan ER 75 Tablet Tablet PR can cause sedation. You should inform your doctor if you are taking any other sleep inducing medicines before starting Depravan ER 75 Tablet Tablet PR.

Is Depravan ER 75 Tablet Tablet PR a psychotropic drug?

Yes. Depravan ER 75 Tablet Tablet PR is a psychotropic drug. Any medication capable of affecting the mind, emotions, and behaviour are called psychotropic drugs.

Is Depravan ER 75 Tablet Tablet PR a narcotic?

No. Depravan ER 75 Tablet Tablet PR is not a narcotic drug. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

What is the difference between Depravan ER 75 Tablet Tablet PR ER and XR?

Both are same medication. Depravan ER 75 Tablet Tablet PR ER and XR both means extended release preparation which releases the medication slowly into the body and maintains a constant needed medications levels. The advantage of taking ER/XR tablets is the frequency of dosage can be decreased.

Can I take mirtazapine along with Depravan ER 75 Tablet Tablet PR?

No. There can be a serious side effect when mirtazapine is taken with Depravan ER 75 Tablet Tablet PR. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Can I take Depravan ER 75 Tablet Tablet PR with citalopram?

No. Citalopram and Depravan ER 75 Tablet Tablet PR both increase serotonin levels. Avoid or use any alternate drug. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

What is the relation between Depravan ER 75 Tablet Tablet PR and p-glycoprotein?

P-glycoprotein is responsible for the expulsion of Depravan ER 75 Tablet Tablet PR from the brain. Some studies have shown that Depravan ER 75 Tablet Tablet PR and its metabolite inhibit the p-glycoprotein.

Where is Depravan ER 75 Tablet Tablet PR absorbed?

Depravan ER 75 Tablet Tablet PR is absorbed from the intestine after being metabolised by the liver.

When should I take Depravan ER 75 Tablet Tablet PR?

Depravan ER 75 Tablet Tablet PR is a medication to treat generalised depressive disorder or depression. Consult your doctor before taking this medication.

Can Depravan ER 75 Tablet Tablet PR cause high blood pressure?

Depravan ER 75 Tablet Tablet PR treatment is associated with sustained increases in blood pressure in some people. It is recommended that people who are being treated with Depravan ER 75 Tablet Tablet PR should have regular monitoring of blood pressure. For such people, either dose reduction or discontinuation should be considered.

Can Depravan ER 75 Tablet Tablet PR cause constipation?

Yes. Depravan ER 75 Tablet Tablet PR is known to cause constipation in some patients. Take a fiber-rich diet and drink plenty of water. You may consider taking laxatives as well. Your doctor will suggest ways to prevent or manage it. Please consult your doctor if it does not resolve or gets worse.

Can Depravan ER 75 Tablet Tablet PR cause weight loss?

Yes. Depravan ER 75 Tablet Tablet PR is known to cause weight loss in some patients. In research studies, a dose-dependent weight loss was noted in patients treated with Depravan ER 75 Tablet Tablet PR for several weeks. Please consult your doctor if it bothers you.

Can Depravan ER 75 Tablet Tablet PR cause addiction?

No. Depravan ER 75 Tablet Tablet PR does not have habit-forming potential.

Can I take Depravan ER 75 Tablet Tablet PR tablet instead of a capsule?

You can take a tablet instead of the capsule but only under consultation or prescription of a doctor. You should not change it yourself as the different formulation of a medication may have a different action as drug release would be different in both. This can lead to an inappropriate treatment and may lead to side effects or even failure of treatment.

Can gabapentin be given along with Depravan ER 75 Tablet Tablet PR?

Yes. Gabapentin can be given with Depravan ER 75 Tablet Tablet PR but only with a consultation of a doctor. They both, when given together, causes an increase drowsiness, sleepiness and decreased concentration in work. Take with caution.

What is the difference between Depravan ER 75 Tablet Tablet PR and desvenlafaxine?

Desvenlafaxine is an active metabolite of Depravan ER 75 Tablet Tablet PR. It is the same medication in an active form.

Can fibromyalgia be treated with Depravan ER 75 Tablet Tablet PR?

Depravan ER 75 Tablet Tablet PR is not approved for the treatment of fibromyalgia. Some research studies have shown promising results of Depravan ER 75 Tablet Tablet PR in the treatment of fibromyalgia. Consult your doctor before starting this medication.

Can nerve pain be treated with Depravan ER 75 Tablet Tablet PR?

Depravan ER 75 Tablet Tablet PR is not approved for treatment of nerve pain disorders but some researchers have proved its efficacy in nerve pain. It is currently used off-label for nerve pain.

Why does Depravan ER 75 Tablet Tablet PR cause loss of appetite?

Depravan ER 75 Tablet Tablet PR is known to cause changes in the neurotransmitters levels and chemicals in the brain which leads to decrease in appetite and this loss of appetite is dose dependent.

What are good alternatives to Depravan ER 75 Tablet Tablet PR, particularly when a side effect is reduced sex drive?

If you find any side effects like decreased sex drive or impotence talk to your doctor and then you can have some other drug. Do not stop Depravan ER 75 Tablet Tablet PR by yourself it can lead to increased adverse effects.
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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Stahl SM, editor. Venlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 721-26.
    2. DeBattista C. Antidepressant Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 513.
    3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1466.
    4. Venlafaxine [FDA Label]. Marietta, GA: Urban Pharmaceuticals Inc.; 1993 [revised Jun. 2014]. [Accessed 19 Mar. 2019] (online) Available from:External Link
    5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Venlafaxine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:External Link
    6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link

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