Defrijet 250 Tablet

Deferasirox (250mg)

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required

Defrijet 250 Tablet is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the body and reduce the risk of it causing organ damage.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 22 May 2026 | 06:22 PM (IST)

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General Information

Contains

Deferasirox (250mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Defrijet 250 Tablet should be taken on an empty stomach. Take it in the exact dose and duration and take it regularly at a fixed time each day to get the maximum benefit from it.

Using of Defrijet 250 Tablet may cause common side effects such as nausea, headache, constipation, and diarrhea. If the side effects persist or worsen, inform your doctor.

Before using this medicine, let your doctor know if you have any kidney or liver diseases. Let your doctor also know about all the other medicines you are taking to ensure your safety.

Uses of Defrijet Tablet

Treatment of Iron overload

Benefits of Defrijet Tablet

Treatment of Iron overload
Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Defrijet 250 Tablet, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Defrijet 250 Tablet as prescribed by the doctor to get the maximum benefit.

Side effects of Defrijet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Defrijet

Nausea
Headache
Vomiting
Rash
Abdominal pain
Constipation
Itching
Abdominal distension
Diarrhea

How to use Defrijet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defrijet 250 Tablet is to be taken on an empty stomach.

How Defrijet Tablet works

Defrijet 250 Tablet traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.

All substitutes for Defrijet 250 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Desirox 250mg Tablet

by Cipla Ltd

₹24.63/tablet

21% costlier

Quick tips

Defrijet 250 Tablet is used to reduce excess iron from the body.
Inform your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
Take an adequate amount of water while taking Defrijet 250 Tablet.
Defrijet 250 Tablet may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
If you are taking any antacid, take them 2 hours before or after Defrijet 250 Tablet.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Defrijet 250 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Defrijet 250 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Defrijet 250 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Defrijet 250 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Defrijet 250 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Defrijet 250 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Defrijet with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Acenocoumarol (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Moderate

Aminophylline (Oral Route)

Do not consume Deferasirox with Aminophylline. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Deferasirox may raise blood levels of Aminophylline.

Moderate

Aminophylline (Injection Route)

Moderate

Carbamazepine (Oral Route)

Your doctor may monitor the effects of Deferasirox along with your overall treatment and adjust the doses as per the observations. Carbamazepine may increase the metabolism of Deferasirox.

Moderate

Cholestyramine (Oral Route)

Do not consume Deferasirox with Cholestyramine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Cholestyramine may reduce blood levels of Deferasirox.

Frequently asked questions

What is Defrijet 250 Tablet used for?

Defrijet 250 Tablet is used for removing excess iron from the body due to repeated blood transfusions in patients with beta thalassemia major (a blood disorder)

How does Defrijet 250 Tablet work?

Defrijet 250 Tablet works by binding to excess iron in the blood and removing it from the body through stool.

Fact Box

Chemical Class

Phenyl- 1,2,4- triazoles

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Iron Chelators

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

References

Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365.
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 6 Apr. 2019] (online) Available from:
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:

User feedback

Patients taking Defrijet 250 Tablet

Once A Day

88%

Twice A Day

Twice A Week

Alternate Day

What are you using Defrijet Tablet for?

Transfusion dependent thalassemia

57%

Iron overload

29%

Others

14%

How much was the improvement?

Average

78%

Excellent

22%

What were the side-effects while using Defrijet 250 Tablet?

No Side Effect

100%

How do you take Defrijet Tablet?

Empty stomach

100%

Please rate Defrijet 250 Tablet on price

Not Expensive

50%

Average

50%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Acme Plaza, Andheri-Kurla Road, Andheri (East), Mumbai, Maharashtra -400059

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Blood Related

Chelating Agents

Defrijet 250 Tablet

Defrijet 250 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Defrijet Tablet

Benefits of Defrijet Tablet

Side effects of Defrijet Tablet

How to use Defrijet Tablet

How Defrijet Tablet works

All substitutes for Defrijet 250 Tablet

Desirox 250mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Acenocoumarol (Oral Route)

Aminophylline (Oral Route)

Aminophylline (Injection Route)

Carbamazepine (Oral Route)

Cholestyramine (Oral Route)

Frequently asked questions

What is Defrijet 250 Tablet used for?

How does Defrijet 250 Tablet work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

References

User feedback

Patients taking Defrijet 250 Tablet

What are you using Defrijet Tablet for?

How much was the improvement?

What were the side-effects while using Defrijet 250 Tablet?

How do you take Defrijet Tablet?

Please rate Defrijet 250 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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