Defagem 6mg/5ml Suspension

Prescription Required
Store at room temperature (10-30°C)

Your Child’s Medicine At a Glance

Defagem 6mg/5ml Suspension belongs to a group of medicines known as corticosteroids. Its anti-inflammatory and immunosuppressive properties give it the ability to treat a wide range of conditions in children. It is also one of the primary medicines used for Duchenne muscular dystrophy in infants and children.

Give Defagem 6mg/5ml Suspension to your child orally, either before or after food. Giving it with food helps prevent the risk of developing a stomach upset. Always give the dose as prescribed by the doctor since that depends on the severity and type of infection, body weight, and age of your child. If your child gains or loses weight during treatment, make sure to let the doctor know. Never alter the dose by yourself as that may increase the risk of serious implications in your child. If your child vomits within 30 minutes of taking this medicine, help the child calm down and repeat the same dose, but skip it if it is already time for the next dose.

It is important to complete the full course of this medicine as stopping it abruptly may cause serious side effects. To stop this medicine, the doctor will gradually taper down the dose of this medicine to avoid withdrawal symptoms. Defagem 6mg/5ml Suspension can suppress your child’s immune system, making your child more prone to infections. Your child may need frequent medical checkups and tests. Therefore, it is important to follow up with your child’s doctor frequently during the treatment. The doctor may also advise vision and bone mineral density check for your child as Defagem 6mg/5ml Suspension can impact both of these.

This medicine may cause side effects like weight gain, increased appetite, upper respiratory tract infection, cough, abnormal hair growth, central obesity, fluid and electrolyte disturbance, and common cold symptoms. Reach out to your child’s doctor if these side effects appear.

Let your child’s doctor know if your child is already taking medicines for any type of infection. Also, narrate your child’s complete medical history, including heart, blood, skin, bone, and hormonal disorders or any prior episodes of allergy, eye disease, birth defects, lung anomaly, liver impairment, and kidney malfunction. This information is critical for dose alterations and in planning your child’s overall treatment.

Uses of Defagem 6mg/5ml Suspension in Children

  • Treatment of Inflammatory conditions
  • Treatment of Autoimmune conditions
  • Treatment of Cancer
  • Treatment of Duchenne muscular dystrophy(DMD)

Benefits of Defagem 6mg/5ml Suspension for your child

In Treatment of Inflammatory conditions

Defagem 6mg/5ml Suspension helps in the treatment of a wide variety of inflammatory conditions such as asthma, severe allergic reactions, juvenile arthritis, uveitis, ulcerative colitis, and Crohn’s disease. Defagem 6mg/5ml Suspension works by inhibiting the secretion of chemicals that cause inflammation like prostaglandins and leukotrienes.

In Treatment of Autoimmune conditions

Defagem 6mg/5ml Suspension has been found useful in organ transplantation and in treating several autoimmune disorders, including rheumatoid arthritis, systemic lupus erythematosus, connective tissue disease, skin disorders, nephrotic syndrome, acute interstitial nephritis, autoimmune hemolytic anemia, and idiopathic thrombocytopenic purpura.

Defagem 6mg/5ml Suspension stops the release of chemical messengers (interleukins) that are required for the multiplication of white blood cells (WBC) in the body. By doing so, it suppresses the body’s immune system and disables it from acting against the body’s organ systems, thereby reducing symptoms such as swelling, pain, itching, and other allergic-type reactions. Because this medicine weakens your child’s immune system, you should avoid having your child near people who are ill or have infections.

In Treatment of Cancer

Defagem 6mg/5ml Suspension helps in the treatment of a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. When given to children, it helps in expediting the system of damaging the cancer cells (apoptosis). It also stops the cancer cells from multiplying. Moreover, it helps to treat or prevent allergic reactions in cancer patients. This medicine also treats nausea and vomiting associated with some chemotherapy medicines. Besides, it is also used to stimulate appetite in cancer patients with severe appetite problems, thus aiding in cancer treatment.

In Treatment of Duchenne muscular dystrophy(DMD)

Duchenne muscular dystrophy (DMD) is a type of muscular dystrophy, characterized by muscle weakness and atrophy due to the effect of the body’s immune system mechanisms. Defagem 6mg/5ml Suspension slows the progression of DMD. The exact mechanism by which it acts is unclear, but it is thought to help mediate the condition by suppressing the immune system. For DMD, Defagem 6mg/5ml Suspension is approved to be used in children above 5 years of age.

Side effects of Defagem 6mg/5ml Suspension in Children

Defagem 6mg/5ml Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Defagem

  • Weight gain
  • Increased appetite
  • Upper respiratory tract infection
  • Cough
  • Frequent urge to urinate
  • Abnormal hair growth
  • Obesity
  • Common cold
  • Electrolyte imbalance

How can I give Defagem 6mg/5ml Suspension to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Defagem 6mg/5ml Suspension may be taken with or without food, but it is better to take it at a fixed time.
Avoid Defagem 6mg/5ml Suspension with salad and vegetable diet.

How Defagem Suspension works

Defagem 6mg/5ml Suspension is a corticosteroid medicine. It acts like the body’s natural anti-inflammatory hormones called glucocorticoids. Defagem 6mg/5ml Suspension decreases the formation of chemical substances like prostaglandins, leukotrienes, and interleukins that are involved in inflammation, allergy, and cell multiplication. It also suppresses the immune system and stops the immune mechanisms from causing any self-damage to the body.

Safety Advice

Defagem 6mg/5ml Suspension is safe to use in patients with kidney disease. No dose adjustment of Defagem 6mg/5ml Suspension is recommended.
Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Defagem 6mg/5ml Suspension to your child.
Defagem 6mg/5ml Suspension should be used with caution in patients with liver disease. Dose adjustment of Defagem 6mg/5ml Suspension may be needed. Please consult your doctor.

What if I forget to give Defagem 6mg/5ml Suspension to my child?

Do not panic. Unless your child’s doctor has advised a specific regime for your child, give the missed dose as soon as you remember it. Skip the missed dose if it is almost the time for the next dose. Do not give a double dose to catch up and follow the prescribed dosing schedule.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Defagem 6mg/5ml Suspension
Zefcort Suspension
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Defsure 6mg/5ml Suspension
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Quick Tips

  • Do not stop taking Defagem 6mg/5ml Suspension suddenly without talking to your doctor first as it may worsen your symptoms.
  • Prefer giving Defagem 6mg/5ml Suspension with food as an empty stomach can trigger acidity and gastric reflux.
  • Avoid giving antacids along with Defagem 6mg/5ml Suspension. If both need to be given, leave a gap of at least 2 hours between administration of Defagem 6mg/5ml Suspension and antacids.
  • Do not give it more often or for longer than advised by your doctor.
  • Defagem 6mg/5ml Suspension can make it harder for your child to fight off infections. Notify your doctor if you notice any signs of infection such as a fever or sore throat.
  • Do not stop the medicine abruptly. Seek the doctor’s guidance to taper the dose gradually as sudden withdrawal may result in a steroid withdrawal syndrome.

Fact Box

Chemical Class
Gluco/mineralocorticoids, progestogins and derivatives
Habit Forming
Therapeutic Class
Action Class

Interaction with Drugs

Taking Defagem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Diadose, Abacus, Disorb
Brand(s): M Spirin, Asalite, Dilsprin
Brand(s): Amom, Samlodon, Amodep
Brand(s): Hospicin B

Patient Concerns

Duchenne Muscular Dystrophy & Developmental delay , speech delay
Dr. Gopal Bansilal Samdani
Your Question is not clear to me . Please ask your question more clearly and in detail and also try be more specific and descriptive.
Babu ke muscular dystrophy genetic problam 48&50gens delite dmd Muscular dystrophy genetic problam medcian pls
Vipul Aggarwal
There are no medcines for It as far as my knowledge is concernedAnd these case are seen by PediatricianPlease let me know if there is any itber way i can help u
Do you have any questions related to Defagem 6mg/5ml Suspension ?

User Feedback


Q. Is Defagem 6mg/5ml Suspension a steroid?

Yes, Defagem 6mg/5ml Suspension is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Defagem 6mg/5ml Suspension increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).

Q. In what conditions should I avoid giving Defagem 6mg/5ml Suspension to my child?

Avoid giving Defagem 6mg/5ml Suspension to your child if they have conditions like cardiac disease or congestive heart failure (except in the presence of active rheumatic carditis), hypertension, thromboembolic disorders, or diabetes mellitus. Defagem 6mg/5ml Suspension should also be avoided if your child has a family history of active TB, active herpes infection, osteoporosis, myasthenia gravis, or renal insufficiency.

Q. What do I need to know about Defagem 6mg/5ml Suspension and my child’s immunizations?

For certain vaccines (live or live-attenuated vaccines), your child will need to wait 4 to 6 weeks before starting Defagem 6mg/5ml Suspension. Hence, your child needs to receive all immunizations according to immunization guidelines before they start taking Defagem 6mg/5ml Suspension.

Q. How can I store Defagem 6mg/5ml Suspension at home?

Keep the medicine in a cool dry place out of the reach of children and pets. This will help avoid any accidental intake.

Q. My child is suffering from a seizure disorder. Is it safe to give Defagem 6mg/5ml Suspension to my child?

Ans: Prolonged intake of Defagem 6mg/5ml Suspension can lead to mental illness as well as a seizure disorder. Therefore, any child who is already suffering from seizure disorder should not take Defagem 6mg/5ml Suspension.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Deflazacort [EMC SmPC]. Reading, UK: Sanofi; 1994 [revised 02 Jan. 2021]. [Accessed 18 Feb. 2021] (online) Available from:External Link
  2. University of Michigan: C.S. Mott Children’s Hospital. Deflazacort. [Updated 19 Ju. 2019]. [Accessed 18 Feb. 2021] (online) Available from:External Link
  3. Memorial Sloan Kettering Cancer Center. Deflazacort. [Accessed 18 Feb. 2021] (online) Available from:External Link
  4. Mayo Clinic: Drugs and Supplements. Deflazacort (Oral Route). [Accessed 18 Feb. 2021] (online) Available from:External Link
  5. Emflaza (deflazacort). Frequently asked questions. [Accessed 18 Feb. 2021] (online) Available from:External Link

Manufacturer/Marketer Address

80-82 LSC, DDA Market, 3rd Floor, J-Block, Vikas Puri, Delhi-18
Country of Origin: India

Expires on or after: June, 2021

A licensed vendor partner from your nearest location will deliver Defagem 6mg/5ml Suspension. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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