

Defsure 6mg/5ml Suspension
Product Summary :
Defsure 6mg/5ml Suspension contains deflazacort, a medicine used to treat Duchenne muscular dystrophy. It helps maintain muscle strength and slow the progression of muscle weakness. It is usually taken once daily, with or without food. Common side effects include weight gain, increased appetite, facial rounding, and cough. Regular monitoring of growth, bone health, blood pressure, and blood sugar is important during treatment.Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Oct 2026 | 02:56 PM (IST)


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Product expires after Jan, 2027
Expiry date may vary by batch. All batches have a 3-month shelf life from the date of dispatch.
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General Information



Your child’s medicine at a glance
Give Defsure 6mg/5ml Suspension to your child orally, either before or after food. Always give the dose as prescribed by the doctor since that depends on the severity and type of infection, body weight, and age of your child. If your child gains or loses weight during treatment, make sure to let the doctor know. Never alter the dose by yourself, as that may increase the risk of serious implications in your child. If your child vomits within 30 minutes of taking this medicine, help the child calm down and repeat the same dose, but skip it if it is already time for the next dose.
It is important to complete the full course of this medicine as stopping it abruptly may cause serious side effects. To stop this medicine, the doctor will gradually taper down the dose of this medicine to avoid withdrawal symptoms. Defsure 6mg/5ml Suspension can suppress your child’s immune system, making your child more prone to infections. Your child may need frequent medical checkups and tests. Therefore, it is important to follow up with your child’s doctor frequently during the treatment. The doctor may also advise vision and bone mineral density check for your child as Defsure 6mg/5ml Suspension can impact both of these.
This medicine may cause side effects like weight gain, increased appetite, upper respiratory tract infection, cough, abnormal hair growth, central obesity, and fluid and electrolyte disturbance. Reach out to your child’s doctor if these side effects appear.
Let your child’s doctor know if your child is already taking medicines for any type of infection. Also, narrate your child’s complete medical history, including heart, blood, skin, bone, and hormonal disorders or any prior episodes of allergy, eye disease, birth defects, lung anomaly, liver impairment, and kidney malfunction. This information is critical for dose alterations and in planning your child’s overall treatment.
Uses of Defsure 6mg/5ml Suspension in children
- Treatment of Duchenne muscular dystrophy(DMD)
Benefits of Defsure 6mg/5ml Suspension for your child
Duchenne muscular dystrophy is a genetic condition that causes gradual muscle weakness, making everyday movements like walking, climbing stairs, and lifting objects increasingly difficult over time. Defsure 6mg/5ml Suspension helps reduce muscle inflammation and damage associated with this condition, which supports better preservation of muscle strength and function. With continued use, it can help slow disease progression, maintain mobility for a longer period, and support overall physical functioning and quality of life.
Side effects of Defsure 6mg/5ml Suspension in children
- Weight gain
- Increased appetite
- Cough
- Pollakiuria
- Excessive hair growth on face
- Central obesity
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Cushing syndrome
- Upper respiratory tract infection
How can I give Defsure 6mg/5ml Suspension to my child?
Avoid Defsure 6mg/5ml Suspension with grapefruit juice.
How Defsure Suspension works
Dosage
Defsure 6mg/5ml Suspension is usually taken once daily, with or without food, as prescribed by your child’s doctor. The dose is determined according to body weight, age, response to treatment, and other medicines being taken. Do not take Defsure 6mg/5ml Suspension with grapefruit juice. Do not stop giving it suddenly, as the dose may need to be reduced gradually.
All substitutes for Defsure 6mg/5ml Suspension
Zefcort Suspension
Mahacort DZ Suspension
Cortimax-XL Suspension
Nestacort Suspension
Defiz Suspension
Quick tips
- Prefer giving Defsure 6mg/5ml Suspension with food as an empty stomach can trigger acidity and gastric reflux.
- Avoid giving antacids along with Defsure 6mg/5ml Suspension. If both need to be given, leave a gap of at least 2 hours between administration of Defsure 6mg/5ml Suspension and antacids.
- Do not give it more often or for longer than advised by your doctor.
- Defsure 6mg/5ml Suspension can make it harder for your child to fight off infections. Notify your doctor if you notice any signs of infection such as a fever or sore throat.
- Do not stop the medicine abruptly. Seek the doctor’s guidance to taper the dose gradually as sudden withdrawal may result in a steroid withdrawal syndrome.
Safety advice

Kidney
Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Defsure 6mg/5ml Suspension to your child.

Liver
Interaction with drugs
Gliclazide (Oral Route)
Glibenclamide (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- University of Michigan: C.S. Mott Children’s Hospital. Deflazacort. [Updated 19 Ju. 2019]. [Accessed 18 Feb. 2021] (online) Available from:
- Memorial Sloan Kettering Cancer Center. Deflazacort. [Accessed 18 Feb. 2021] (online) Available from:
- Emflaza (deflazacort). Frequently asked questions. [Accessed 18 Feb. 2021] (online) Available from:
- Deflazacort [Prescribing Information]. Northbrook, IL: Marathon Pharmaceuticals, LLC; 2017. [Accessed 20 Feb. 2024] (online) Available from:
- Deflazacort [Prescribing Information]. Hyderabad, India: Aurobindo Pharma Limited; 2024.[Accessed 11 Mar. 2026] (online) Available from:
- Deflazacort. Hyderabad, Telangana: Aurobindo Pharma Limited; 2026. [Accessed 05 Jan. 2026] (online). Available from:




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Marketer details
Address: Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072.
Vendor Details
A licensed vendor partner from your nearest location will deliver Defsure 6mg/5ml Suspension. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)



