Ddretro 400mg Tablet

Didanosine (400mg)

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Ddretro 400mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 06 May 2026 | 05:19 PM (IST)

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General Information

Contains

Didanosine (400mg)

Marketer

Alkem Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Ddretro 400mg Tablet is used in the treatment of HIV infections

Uses of Ddretro Tablet

HIV infection

Benefits of Ddretro Tablet

HIV infection
HIV infection damages the immune system by attacking cells that protect the body from infections. Ddretro 400mg Tablet helps control the infection by reducing the amount of virus in the body. This supports the immune system, lowers the risk of HIV-related illnesses, and improves overall health and quality of life when taken as part of combination therapy.

Side effects of Ddretro Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ddretro

Headache
Nausea
Rash
Vomiting
Diarrhea
Pancreatic inflammation
Elevated serum glutamic oxaloacetic transaminase
Elevated serum glutamic pyruvic transaminase
Increased lipase in the blood

How to use Ddretro Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ddretro 400mg Tablet is to be taken on an empty stomach.

How Ddretro Tablet works

Ddretro 400mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Quick tips

In combination with other medicines, it is used for the treatment of HIV infections.
Take it with food, as this increases the absorption of the medicine into the body.
Ddretro 400mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
You may still develop infections or other illnesses associated with viral infection while taking this medication.
You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.
You have been prescribed Ddretro 400mg Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
In combination with other medicines, it is used for the treatment of HIV infections.
Take it with food, as this increases the absorption of the medicine into the body.
Ddretro 400mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
You may still develop infections or other illnesses associated with viral infection while taking this medication.
You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Ddretro 400mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Ddretro 400mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Ddretro 400mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

SAFE

Ddretro 400mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Ddretro 400mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Ddretro 400mg Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Ddretro with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Ribavirin (Oral Route)

Do not consume Didanosine with Ribavirin.

Severe

Tenofovir disoproxil fumarate (Oral Route)

Do not consume Tenofovir disoproxil fumarate with Didanosine. If concurrent use is essential, watch out for symptoms such as blurred vision, nausea, chills, common cold, cough, decreased appetite, rash, anxiety or bleeding gums and consult your doctor if you experience them. They may monitor your treatment, kidney functioning and adjust the doses as per the observations.

Severe

Allopurinol (Oral Route)

Do not consume Didanosine with Allopurinol. Allopurinol may raise blood levels of Didanosine.

Severe

Isoniazid (Oral Route)

Do not consume Didanosine with Isoniazid.

Severe

Stavudine (Oral Route)

Do not use Didanosine with Stavudine. If concurrent use is essential, talk to your doctor.

Frequently asked questions

What is Ddretro 400mg Tablet? What is it used for?

How does Ddretro 400mg Tablet work?

Ddretro 400mg Tablet prevents the multiplication of the virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Is Ddretro 400mg Tablet safe?

Ddretro 400mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

How should I take Ddretro 400mg Tablet?

Ddretro 400mg Tablet should be taken in the dose and duration advised by the doctor. This medicine is to be taken on an empty stomach to get maximum benefit. It is better to take Ddretro 400mg Tablet at a fixed time of the day to avoid the chances of missing a dose.

Is Ddretro 400mg Tablet effective?

Ddretro 400mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Ddretro 400mg Tablet too early, the symptoms may return or worsen.

What if I forget to take a dose of Ddretro 400mg Tablet?

If you forget a dose of Ddretro 400mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Fact Box

Chemical Class

Purine 2',3'- dideoxyribonucleosides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

References

Flexner C. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1638-40.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 858.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 399-401.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Ddretro 400mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Ddretro 400mg Tablet

Cash on delivery

Free Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Ddretro Tablet

Benefits of Ddretro Tablet

Side effects of Ddretro Tablet

How to use Ddretro Tablet

How Ddretro Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ribavirin (Oral Route)

Tenofovir disoproxil fumarate (Oral Route)

Allopurinol (Oral Route)

Isoniazid (Oral Route)

Stavudine (Oral Route)

Frequently asked questions

What is Ddretro 400mg Tablet? What is it used for?

How does Ddretro 400mg Tablet work?

Is Ddretro 400mg Tablet safe?

How should I take Ddretro 400mg Tablet?

Is Ddretro 400mg Tablet effective?

What if I forget to take a dose of Ddretro 400mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests