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11 Dec 2019 | 01:27 PM (IST)
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Cyrin 100mg Capsule


Overview

Introduction

Cyrin 100mg Capsule is used to prevent your body rejecting a new organ after a liver, kidney or heart transplant. It works by weakening your immune system so that your body does not attack the new organ. It can also be used to treat a skin complaint called psoriasis and severe rheumatoid arthritis.

The amount of Cyrin 100mg Capsule you take depends on your weight, medical condition and what you are taking it for. Your doctor will plan the correct dose for you. Do not change the dose without talking to your doctor. It can be taken with or without food but take it, in the same way, each time and at the same time every day to get the most benefit. Keep taking these tablets for as long as you have been told to, even if you feel well. Stopping treatment may increase the risk of your transplanted organ being rejected.

The most common side effects of this medicine include headache, unusual growth of facial or body hair, high blood pressure, diarrhea and shaking or tremors. Because it lowers your immune system, you may also catch more infections than usual. Tell your doctor straight away if you develop an infection. For the same reason, you may be more at risk of developing some cancers, particularly of the skin. You should limit your exposure to sunlight.

Before taking this medicine you should tell your doctor if you have liver or kidney problems, high blood pressure, gout(increased uric acid levels in the blood) or epilepsy. Also, tell your doctor about all other medicines you are taking as they may affect the working of the medicine. This medicine should only be used in pregnancy if it is clearly needed and is not recommended while breastfeeding. You will have frequent medical tests while taking this medicine to check your blood pressure, liver and kidney function and mineral levels. This may lead to changes in your dose.

Side effects of Cyrin Capsule

Common
  • Headache
  • Nausea
  • Vomiting
  • Increased hair growth
  • High blood pressure
  • Renal dysfunction
  • Loss of appetite
  • Diarrhea
  • Tremor

How to use Cyrin Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Cyrin 100mg Capsule is to be taken with food.

How Cyrin Capsule works

Cyrin 100mg Capsule is an immunosuppressant. It works by suppressing your body’s immune response to help accept a newly transplanted organ (eg. liver, kidney, heart). In rheumatoid arthritis, this immunosuppressive effect reduces inflammation (swelling) of joints and limits joint damage. In psoriasis, it works by reducing the activity of certain immune cells that cause overproduction of skin cells, thus improving scaling and redness.

Safety Advice

Alcohol
SAFE
Consuming alcohol with Cyrin 100mg Capsule does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Cyrin 100mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
UNSAFE
Cyrin 100mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Cyrin 100mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Cyrin 100mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Cyrin 100mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Cyrin 100mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Cyrin 100mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.

What if you forget to take Cyrin Capsule?

If you miss a dose of Cyrin 100mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Cyrin 100mg Capsule
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Quick Tips

  • Cyrin 100mg Capsule is used to prevent organ rejection in transplant patients. 
  • It is also used to treat arthritis and immune disorders of the eyes, lungs, muscles, skin, nerves, and blood vessels.
  • It may take 3 to 4 months for the medication to work. Keep taking it as prescribed.
  • Your doctor may get regular blood tests done to check the levels of blood cells in your blood. Inform your doctor if you experience unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness. 
  • Your doctor may monitor your kidney function regularly. Drink 8 to 10 glasses of water per day to help with your kidney function.
  • Do not stop taking Cyrin 100mg Capsule without talking to your doctor first.

Interaction with Drugs

Taking Cyrin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Rotasiil, Rotarix, RotaTeq
LIFE-THREATENING
LIFE-THREATENING
Brand(s): Abhay M, Measles, M-Vac
LIFE-THREATENING
Brand(s): Rubella
LIFE-THREATENING

Patient Concerns

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My joint of my fingers and toes become stiff and painful in the morning while wake up and also feelung mild pain in my heart. I have been diagonised rheumatoid arthritis.
Dr. Akshat Goel
Bone & Joint Specialist
Please refer to a RheumatologistApply Dynapar QPS spray and take Tab Zerodol-SP twice daily and Tab Saaz 500mg twice daily and Tab HCQS-200 once daily
My mother has problem of rheumatoid arthritis since 2 years i want to ask can homeopathy cure dis problem if it can be treated than how many time it takes to cure and what treatment should be taken
Dr. Saurav Arora
Homeopathy
Dear sir this problem can surely be treated with homeopathy but as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly. The duration of treatment in different cases.
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Do you have any questions related to Cyrin 100mg Capsule ?

FAQs

Q. Is Cyrin a steroid?

No, Cyrin is not a steroid. This belongs to a group of medicines known as immunosuppressive agents. It decreases the action of the body’s immune system.

Q. Can Cyrin cause weight gain?

Cyrin may either cause an increase or decrease in weight. However, the changes in weight are uncommon side effects of this medicine. Consult your doctor if these side effects worry you.

Q. Does Cyrin cause hair growth?

Yes, the use of Cyrin may cause abnormal hair growth (hypertrichosis) as a common side effect of Cyrin, though it does not affect everyone.

Q. Does Cyrin cause fatigue?

Yes, Cyrin may cause fatigue as a common side effect. However, fatigue could also be due to an underlying disease. Discuss with your doctor if this side effect worries you.

Q. Do I need to get any tests done while being treated with Cyrin?

Yes, the doctor may suggest tests to check the levels of Cyrin in your blood, especially if you have had a transplant. You may also be advised to get your blood pressure checked before the start of your treatment and regularly during treatment. In addition, liver and kidney function tests along with your blood lipids (fats), will be checked.

Q. Can Cyrin cause cancer?

Cyrin is known to suppress the immune system. This as a result, increases your risk of developing cancers, particularly of the skin and lymphoid system. You should limit your exposure to sunlight and UV light by wearing appropriate protective clothing. Sunscreen should be applied frequently with a high protection factor.

Q. What are the side effects of Cyrin?

Cyrin may cause side effects such as headache, diarrhea, heartburn, increased hair growth on the face, arms, or back, growth of extra tissue on the gums, acne, flushing, and uncontrollable shaking of a part of your body. You may also experience burning or tingling sensation in the hands, arms, feet, or legs, muscle or joint pain, cramps, pain or pressure in the face, ear problems, breast enlargement in men, depression and difficulty falling asleep or staying asleep.

Q. How should Cyrin be taken?

Take Cyrin strictly as advised by your doctor. The doctor will decide and carefully adjust your dose according to your medical requirements. It is important to keep a constant amount of Cyrin in the body, and hence, the medicine should be taken at the same time each day. Not only is the time of day important, but also when Cyrin is taken in relation to meals.

Q. How long do I need to take Cyrin?

Take Cyrin for as long as the doctor has advised. The duration of treatment depends on whether you are taking it after a transplant or for the treatment of other conditions. Usually, the treatment may last for 8 weeks if you are taking it for severe rash.

Q. What is Cyrin used for?

Cyrin is used in combination with other medications which are used to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have received kidney, liver, and heart transplants. These combination medicines also help to treat the symptoms of rheumatoid arthritis (a disease, affecting the joints with pain and swelling) in patients whose symptoms were not relieved by methotrexate alone, to treat psoriasis (a skin disease in which red, scaly patches form on some areas of the body), and atopic dermatitis (skin allergies).

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References
  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1821.
  2. Wallace JL, Sharkey KA. Pharmacotherapy of Inflammatory Bowel Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1358-59.
  3. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 630-31.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 340-42.
  5. Ciclosporine. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1983 [revised 24 Jul. 2015]. [A cessed 25 Jan. 2019].(online) Available from:External Link
  6. Drugs.com. Cyclosporine. [Accessed 06 Apr. 2019] (online) Available from:External Link
  7. Cyclosporine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation. [Accessed 06 Apr. 2019] (online) Available from:External Link
  8. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Claris Corporate Headquarters, Nr. Parimal Crossing, Ellisbridge, Ahmedabad - 380 006, India.
A licensed pharmacy from your nearest location will deliver Cyrin 100mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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