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Last updated on:
09 Sep 2019 | 11:46 AM (IST)
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Cyclomune 50 mg Tablet


Overview

Cyclomune Tablet side effects

Common
  • Headache
  • Nausea
  • Vomiting
  • Increased hair growth
  • High blood pressure
  • Renal dysfunction
  • Loss of appetite
  • Diarrhea
  • Tremor

How to use Cyclomune Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cyclomune 50 mg Tablet is to be taken with food.

How Cyclomune Tablet works

Cyclomune 50 mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response to help accept a newly transplanted organ (eg. liver, kidney, heart). In rheumatoid arthritis, this immunosuppressive effect reduces inflammation (swelling) of joints and limits joint damage. In psoriasis, it works by reducing the activity of certain immune cells that cause overproduction of skin cells, thus improving scaling and redness.

Cyclomune Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Cyclomune 50 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
UNSAFE
Cyclomune 50 mg Tablet is unsafe to use during lactation. Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Driving
It is not known whether Cyclomune 50 mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Cyclomune 50 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Cyclomune 50 mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Cyclomune 50 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Cyclomune 50 mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.

What if you miss a dose of Cyclomune Tablet?

If you miss a dose of Cyclomune 50 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Cyclomune 50 mg Tablet
₹36.5/Tablet
Graftin 50mg Tablet
Sun Pharmaceutical Industries Ltd
₹51.36/Tablet
41% costlier
Esporine 50mg Tablet
Zanetaz Medicorp
₹53.28/Tablet
46% costlier

Expert Advice

  • Cyclomune 50 mg Tablet is used to prevent organ rejection in transplant patients. 
  • It is also used to treat arthritis and immune disorders of the eyes, lungs, muscles, skin, nerves, and blood vessels.
  • It may take 3 to 4 months for the medication to work. Keep taking it as prescribed.
  • Your doctor may get regular blood tests done to check the levels of blood cells in your blood. Inform your doctor if you experience unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness. 
  • Your doctor may monitor your kidney function regularly. Drink 8 to 10 glasses of water per day to help with your kidney function.
  • Do not stop taking Cyclomune 50 mg Tablet without talking to your doctor first.

Interaction with Drugs

Taking Cyclomune with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Begenta, Indogenta, Spagen
SERIOUS
Brand(s): Indizole, Itracip, Itraspan
SERIOUS
Brand(s): Stoin, Marantin
SERIOUS
SERIOUS
Brand(s): Antep
SERIOUS
Brand(s): Shinosun
SERIOUS
Brand(s): Auxicasp, Canducid
SERIOUS
Brand(s): Had Q
SERIOUS
Brand(s): Samwell
SERIOUS

Patient Concerns

Questions Related to Cyclomune

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I have stop tablet for last six months for Rhematology , but today had a serious pain in left hand , what is tablets now ?
Dr. Vipul Aggarwal
Bone & Joint Specialist
u are not supposed to stop treatment all of a sudden if u are taking it for rheumatoid arthritis u can take tab etoshine 90 mg sosbetter get a follow up down its ur docotor
My mother is suffering from interstitial lung dieses and she is taking azithioprine 50mg and prednisolone 10 mg from last 4 years .she is feeling good.so we try to reduce the dose but after reducing the dose coughing gets started.kindly tell us that is their any permanent solution of this dieses or any medicine which you want to add?kindly give your feedback on my email id.thanksNON SPECIFIC INTERSTITIAL PNEUMONITIS- CAUSE RHEMATOID ARTHRITIS DIABETES MELLITUS RHEUMATOID ARTHRITISReport of ct hogh resolution thorex LUNGS AND PLEURA: * Irregular reticular lines, ground glass opacity and architectural distortion in the form of traction bronchiolectasis, with basal and subpleural predominance * Pleural thickening near sites of parenchymal involvement TRACHEA AND MAIN BRONCHI: nil significant ADENOPATHY: * Mediastinal nodes up to 9 mm CARDIA AND GREAT VESSELS: nil significant * MPA - 20 mm ESOPHAGUS, THYMUS: nil significant CHEST WALL: nil significant BONES: degenerative changes of spine VISUALIZED UPPER ABDOMEN: No focal lesions in liver / spleen /adrenals / pancreas IMPRESSION: --- Overall features of mild disease regressionSpirometry test report excludes an obstructive ventilatory defect at the time of testing. The low FVC is suggestive of restrictive process.Would suggest testing lung volumes and DLCO for confirmation and quantification, if clinically indicated.
Dr. Anshum Aneja Arora
Lungs Specialist
Your mother is suffering from Rheumatoid - arthritis induced ILD. Since ILD occuring secondary to a disease requires complete control of underlying diseas, it is important that your mother is seen by a rheumatologist as well as Pulmonologist.A rheumatologist may add further treatment which in turn also prevents progression of ILD. also, DLCO testing is important.Further treatment options are available. U can get her reviewed .PLease read :http://www.arohealth.com/interstitial-lung-disease/ for more information on ILD
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FAQs

Q. Is Cyclomune a steroid?

No, Cyclomune is not a steroid. This belongs to a group of medicines known as immunosuppressive agents. It decreases the action of the body’s immune system.

Q. Can Cyclomune cause weight gain?

Cyclomune may either cause an increase or decrease in weight. However, the changes in weight are uncommon side effects of this medicine. Consult your doctor if these side effects worry you.

Q. Does Cyclomune cause hair growth?

Yes, the use of Cyclomune may cause abnormal hair growth (hypertrichosis) as a common side effect of Cyclomune, though it does not affect everyone.

Q. Does Cyclomune cause fatigue?

Yes, Cyclomune may cause fatigue as a common side effect. However, fatigue could also be due to an underlying disease. Discuss with your doctor if this side effect worries you.

Q. Do I need to get any tests done while being treated with Cyclomune?

Yes, the doctor may suggest tests to check the levels of Cyclomune in your blood, especially if you have had a transplant. You may also be advised to get your blood pressure checked before the start of your treatment and regularly during treatment. In addition, liver and kidney function tests along with your blood lipids (fats), will be checked.

Q. Can Cyclomune cause cancer?

Cyclomune is known to suppress the immune system. This as a result, increases your risk of developing cancers, particularly of the skin and lymphoid system. You should limit your exposure to sunlight and UV light by wearing appropriate protective clothing. Sunscreen should be applied frequently with a high protection factor.

Q. What are the side effects of Cyclomune?

Cyclomune may cause side effects such as headache, diarrhea, heartburn, increased hair growth on the face, arms, or back, growth of extra tissue on the gums, acne, flushing, and uncontrollable shaking of a part of your body. You may also experience burning or tingling sensation in the hands, arms, feet, or legs, muscle or joint pain, cramps, pain or pressure in the face, ear problems, breast enlargement in men, depression and difficulty falling asleep or staying asleep.

Q. How should Cyclomune be taken?

Take Cyclomune strictly as advised by your doctor. The doctor will decide and carefully adjust your dose according to your medical requirements. It is important to keep a constant amount of Cyclomune in the body, and hence, the medicine should be taken at the same time each day. Not only is the time of day important, but also when Cyclomune is taken in relation to meals.

Q. How long do I need to take Cyclomune?

Take Cyclomune for as long as the doctor has advised. The duration of treatment depends on whether you are taking it after a transplant or for the treatment of other conditions. Usually, the treatment may last for 8 weeks if you are taking it for severe rash.

Q. What is Cyclomune used for?

Cyclomune is used in combination with other medications which are used to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have received kidney, liver, and heart transplants. These combination medicines also help to treat the symptoms of rheumatoid arthritis (a disease, affecting the joints with pain and swelling) in patients whose symptoms were not relieved by methotrexate alone, to treat psoriasis (a skin disease in which red, scaly patches form on some areas of the body), and atopic dermatitis (skin allergies).

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References
  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1821.
  2. Wallace JL, Sharkey KA. Pharmacotherapy of Inflammatory Bowel Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1358-59.
  3. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 630-31.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 340-42.
  5. Ciclosporine. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1983 [revised 24 Jul. 2015]. [A cessed 25 Jan. 2019].(online) Available from:External Link
  6. Drugs.com. Cyclosporine. [Accessed 06 Apr. 2019] (online) Available from:External Link
  7. Cyclosporine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation. [Accessed 06 Apr. 2019] (online) Available from:External Link
  8. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:External Link
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