Curifix 400mg Tablet
Prescription Required
View available alternative with same salt composition
Product introduction
Curifix 400mg Tablet is an antibiotic that treats hepatic encephalopathy, a condition in which the liver fails to remove harmful toxins from the blood, leading to brain damage. It works by killing and stopping the growth of harmful bacteria in the intestines.
This medicine can be used alone or in combination with other medicines. It may be taken with or without food, preferably at the same time, each day. It should be used in the dose and duration as advised by the doctor. Take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat.
Some people may develop side effects like headache, dizziness, nausea, rashes, joint pain, and depression. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away. Your urine may become reddish in color due to this medicine. But, it is normal and harmless.
Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any medicine.
Uses of Curifix Tablet
- Treatment of Infectious diarrhea
Benefits of Curifix Tablet
In Treatment of Infectious diarrhea
Infectious diarrhea is a condition characterized by the sudden onset of loose or watery stools caused by harmful microorganisms in the digestive system. Curifix 400mg Tablet helps treat infectious diarrhea by targeting and stopping the growth of harmful bacteria in the intestines. This medicine interferes with the bacteria's ability to make important proteins they need to survive and multiply. This helps to get rid of the bad bacteria causing the infection, which in turn reduces the diarrhea and helps you feel better.
Side effects of Curifix Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Curifix
- Dizziness
- Nausea
- Peripheral edema
- Ascites (accumulation of fluid in the abdominal cavity)
- Depression
- Joint pain
- Rash
- Muscle pain
- Headache
- Breathing problems
- Stomach pain
- Diarrhea
How to use Curifix Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Curifix 400mg Tablet may be taken with or without food.
How Curifix Tablet works
Curifix 400mg Tablet is an antibiotic. It works by killing the ammonia-producing bacteria in the digestive tract. This treats your infection and relieves symptoms of hepatic encephalopathy (agitation, confusion, muscle problems). This also helps reduce the recurrence of episodes of hepatic encephalopathy.
Safety advice
Alcohol
UNSAFE
Do not drink alcohol while you are taking this medicine. Curifix 400mg Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Curifix 400mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Curifix 400mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Curifix 400mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Curifix 400mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Curifix 400mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
What if you forget to take Curifix Tablet?
If you miss a dose of Curifix 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Curifix 400mg Tablet
₹23.7/Tablet
Rexigut 400mg Tablet
Leeford Healthcare Ltd
₹24.1/tablet
2% costlier
Rifaford 400mg Tablet
Leeford Healthcare Ltd
₹25.8/tablet
9% costlier
Rifagut 400 Tablet
Sun Pharmaceutical Industries Ltd
₹38.4/tablet
62% costlier
Rcifax 400 Tablet
Lupin Ltd
₹43.8/tablet
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Rifastop 400 Tablet
Mankind Pharma Ltd
₹35.3/tablet
49% costlier
Quick tips
- Curifix 400mg Tablet reduces the risk of overt hepatic encephalopathy (HE) recurrence in patients with liver disease.
- It may cause reddish discoloration of urine. This is normal and harmless.
- Stop taking Curifix 400mg Tablet and inform your doctor if you have severe diarrhea during or after using Curifix 400mg Tablet.
- Finish the full course of the medication, even if you feel better.
Fact Box
Chemical Class
Macrolactams
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
RNA polymerase inhibitors- Rifamycins
Interaction with drugs
Taking Curifix with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Watch out for symptoms of Rifaximin side effects such as diarrhea, dizziness, swelling or fatigue and consult your doctor if you experience them. They may adjust the doses as per t
Watch out for symptoms of Rifaximin side effects such as diarrhea, dizziness, swelling or fatigue and consult your doctor if you experience them. They may adjust the doses as per t
Watch out for symptoms of Rifaximin side effects such as diarrhea, dizziness, swelling or fatigue and consult your doctor if you experience them. They may adjust the doses as per t
Watch out for symptoms of Rifaximin side effects such as diarrhea, dizziness, swelling or fatigue and consult your doctor if you experience them. They may adjust the doses as per t
Watch out for symptoms of Rifaximin side effects such as diarrhea, dizziness, swelling or fatigue and consult your doctor if you experience them. They may adjust the doses as per t
Patient concerns
User feedback
What are you using Curifix Tablet for?
Others
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How much was the improvement?
Average
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What were the side-effects while using Curifix 400mg Tablet?
No Side Effec*
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*No Side Effect
How do you take Curifix Tablet?
With food
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Please rate Curifix 400mg Tablet on price
Not Expensive
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FAQs
Should I take Curifix 400mg Tablet with food?
Yes, Curifix 400mg Tablet can be taken orally with or without food with a glass of water. Take it as prescribed by your doctor for the exact period of time.
What does Curifix 400mg Tablet do for the liver?
In liver disease, there is an increased growth of bacteria in the intestine which increases the load of toxins travelling through the body. This further increases the possibility of toxins reaching the brain which can cause abnormal brain function. Curifix 400mg Tablet slows down the growth of bacteria in the gut, decreasing the symptoms in cases of liver disease.
Can Curifix 400mg Tablet cause weight gain?
Usually Curifix 400mg Tablet does not cause weight gain. However, in case you feel there is an increase in weight, you should consult your doctor to determine the reason of weight gain.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1215-16.
- Rifaximin [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2015. [Accessed 05 Aug. 2023] (online) Available from:
- CiplaMed. Rifaximin [Prescribing Information]. [Accessed 05 Aug. 2023] (online) Available from:
- Rifaximin. Uxbridge, UK: Norgine Pharmaceuticals Ltd.; 2025 [Accessed 16 Feb. 2026] (online). Available from:
Marketer details
Name: Alvio Pharma
Address: Signature-2 Business Park Sanand - Sarkhej Road, Sarkhej Cir, Ahmedabad, Gujarat 382210
Country of origin: India
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₹237
Inclusive of all taxes
MRP₹262.5 10% OFF
10.0 tablets in 1 strip
SOLD OUT
Available alternative with same salt composition
Rifaford 400mg Tablet
strip of 10 tablets
by Leeford Healthcare Ltd
Get by Tomorrow
₹258
35% off
Rifaximin (400mg)