Crizalk 250mg Capsule

Crizotinib (250mg)

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Crizalk 250mg Capsule is used in the treatment of non-small cell lung cancer that is locally advanced or has spread to other areas of the body.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)

₹95931

₹106602.35

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60 capsules

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Gurgaon

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General Information

Contains

Crizotinib (250mg)

Marketer

Pfizer Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Crizalk 250mg Capsule should be taken with food or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, edema (swelling), and diarrhea are some common side effects of this medicine. Some serious side effects that might occur which need doctor consultation include severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits. Your doctor may perform some blood tests during the treatment to check for liver function.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Crizalk Capsule

Non-small cell lung cancer

Benefits of Crizalk Capsule

Non-small cell lung cancer
Non-small cell lung cancer is the most common type of lung cancer, often linked to smoking and environmental exposure. It typically grows and spreads more slowly than small-cell lung cancer but can still be life-threatening if not treated early. Crizalk 250mg Capsule is used in patients whose tumors have specific genetic changes. It works by blocking these abnormal proteins that promote cancer cell growth. By targeting the root cause of tumor development, Crizotinib can slow or stop cancer progression, reduce tumor size, and improve overall survival and quality of life.

Side effects of Crizalk Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Crizalk

Dizziness
Vision disorder
Gastrointestinal toxicity
Increased transaminase level in blood
Upper respiratory tract infection
Abnormal blood cell count
Fatigue
Edema (swelling)
Decreased appetite
Neuropathy

How to use Crizalk Capsule

Take this medicine in the dose and duration as advised by your doctor. Crizalk 250mg Capsule may be taken with or without food.

How Crizalk Capsule works

Crizalk 250mg Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Quick tips

Crizalk 250mg Capsule helps in the treatment of non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
Take it at the same time each day, with or without food.
Diarrhea, nausea and vomiting may occur with Crizalk 250mg Capsule. Stay hydrated and inform your doctor if it persists.
It may cause dizziness or blurring of vision. Don't drive or do anything requiring concentration until you know how it affects you.
Inform your doctor if you experience severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits.
Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
Do not take Crizalk 250mg Capsule if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Crizalk 250mg Capsule. Please consult your doctor.

Pregnancy

UNSAFE

Crizalk 250mg Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Crizalk 250mg Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Crizalk 250mg Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Crizalk 250mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Crizalk 250mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Crizalk 250mg Capsule may not be advised in patients with the severe liver disease.

Interaction with drugs

Taking Crizalk with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Aripiprazole (Oral Route)

Do not consume Aripiprazole with Crizotinib.

Life-threatening

Ondansetron (Oral Route)

Do not consume Ondansetron with Crizotinib.

Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Crizotinib.

Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Crizotinib. Crizotinib may raise blood levels of Domperidone.

Life-threatening

Tetrabenazine (Oral Route)

Do not consume Tetrabenazine with Crizotinib.

Frequently asked questions

How is Crizalk 250mg Capsule administered?

Crizalk 250mg Capsule is generally administered in the form of capsules to be taken orally.

What is Crizalk 250mg Capsule used for?

Crizalk 250mg Capsule is used for treating non small-cell lung cancer caused due to a mutation or defect in a gene called as anaplastic lymphoma kinase in cancer cells in patients who have not responded to previous therapies.

How does Crizalk 250mg Capsule work?

Crizalk 250mg Capsule works by inhibiting an enzyme called as tyrosine kinase that transmits the signal for growth and spread of cancer cells.

Fact Box

Chemical Class

Pyrazolopyridine derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 331.
Crizotinib. Dublin, Ireland: Pfizer Ireland Pharmaceuticals; Aug. 2011. [Accessed 26 Mar. 2019] (online) Available from:
Crizotinib. Bruxelles Belgium: Pfizer Europe; 23 Oct. 2012 [revised Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Crizotinib. New York, NY: Pfizer Labs; 2023 [Accessed 08 Jan. 2026] (online). Available from:
Crizotinib. New York, NY: Pfizer Labs; 2022 [Accessed 08 Jan. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Crizalk 250mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Crizalk 250mg Capsule

Payment

Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Crizalk Capsule

Benefits of Crizalk Capsule

Side effects of Crizalk Capsule

How to use Crizalk Capsule

How Crizalk Capsule works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aripiprazole (Oral Route)

Ondansetron (Oral Route)

Hydroxyzine (Oral Route)

Domperidone (Oral Route)

Tetrabenazine (Oral Route)

Frequently asked questions

How is Crizalk 250mg Capsule administered?

What is Crizalk 250mg Capsule used for?

How does Crizalk 250mg Capsule work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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