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CPZ 50 Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 22 Sep 2025 | 12:25 AM (IST)
CPZ 50 Tablet is a medicine used to treat various disorders such as schizophrenia and other psychoses like paranoia (delusions and feeling extremely worried or nervous), mania (overactive behavior), anxiety, agitation, and dangerously impulsive behavior.
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General Information

The content is shown in English
CPZ 50 Tablet image
CPZ 50 Tablet image
CPZ 50 Tablet image

Product introduction

CPZ 50 Tablet is also used for controlling intractable hiccups, feeling or being sick (nausea), and autism (learning and communication difficulties). This medicine belongs to a group of drugs known as phenothiazines, which act on the central nervous system. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.

CPZ 50 Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly.

Before taking this medicine, inform your doctor if you have any liver disease, thyroid or kidney disease, epilepsy, Parkinson’s disease, or any heart disease. If you are diabetic, it is important to monitor your blood glucose regularly while taking this medicine.

Benefits of CPZ Tablet

Treatment of Anxiety
CPZ 50 Tablet reduces the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, and feeling irritable. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping it suddenly can cause serious problems. So, do not stop taking it without discussing it with your doctor.
Treatment of Mania
Mania means extremely excited or elevated mood. CPZ 50 Tablet helps calm the mood and relax the nerves. This stabilizes the mood and prevents the symptoms of mania from recurring again. Taking CPZ 50 Tablet will ensure that you have a better social life and can do daily activities more comfortably.

Side effects of CPZ Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of CPZ
  • Weight gain
  • Dryness in mouth
  • Sleepiness
  • Constipation
  • Extrapyramidal symptoms
  • Sedation

How to use CPZ Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. CPZ 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How CPZ Tablet works

CPZ 50 Tablet is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Quick tips

  • Take it at night to avoid feeling sleepy during the day.
  • Do not drive or do anything requiring concentration until you know how CPZ 50 Tablet affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Do not drink alcohol while taking CPZ 50 Tablet as it can cause serious breathing problems.
  • Inform your doctor if you notice involuntary muscle movements.
  • Monitor your weight during the treatment as CPZ 50 Tablet can cause weight gain.
  • Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with CPZ 50 Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
CPZ 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
CPZ 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
If the CPZ 50 Tablet is given, monitor the baby for excessive sleepiness during breastfeeding.
Driving

Driving

UNSAFE
CPZ 50 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
CPZ 50 Tablet is safe to use in patients with kidney disease. No dose adjustment of CPZ 50 Tablet is recommended.
However, inform your doctor if you have any underlying kidney disease. A close monitoring is advisable while you are taking this medicine.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of CPZ 50 Tablet in patients with liver disease. Please consult your doctor.

Interaction with drugs

Taking CPZ with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Sildenafil (Oral Route)

Do not consume Chlorpromazine with Sildenafil. Concomitant use may affect heart rhythm and can be fatal.
Life-threatening

Sildenafil (Oral Route)

Do not consume Chlorpromazine with Sildenafil. Concomitant use may affect heart rhythm and can be fatal.
Life-threatening

Sildenafil (Injection Route)

Do not consume Chlorpromazine with Sildenafil. Concomitant use may affect heart rhythm and can be fatal.
Life-threatening

Sildenafil (Injection Route)

Do not consume Chlorpromazine with Sildenafil. Concomitant use may affect heart rhythm and can be fatal.
Life-threatening

Sildenafil (Oral Route)

Do not consume Chlorpromazine with Sildenafil. Concomitant use may affect heart rhythm and can be fatal.

Frequently asked questions

CPZ 50 Tablet is not a benzodiazepine. It belongs to a class of medicines called phenothiazine antipsychotics. CPZ 50 Tablet should not be used as a sleeping tablet
It is used in patients with schizophrenia but it relieves anxiety too at certain levels
No. CPZ 50 Tablet is not a controlled substance/ narcotic. However, it can be purchased only after producing a doctor's prescription
Yes, CPZ 50 Tablet may cause weight gain and sleepiness
Chlorpromazine does not have high addictive potential and a very little propensity for abuse for euphoria
Chlorpromazine is dopamine receptor blocker so it decreases dopamine levels to calm the patients with schizophrenia
It has been observed that CPZ 50 Tablet helps in certain cases of opiate withdrawal. However, it is not widely used for this purpose. Please follow your doctor's advice regarding its use.

Fact Box

Chemical Class

Phenothiazine Derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Typical Antipsychotics

References

  1. Stahl SM, editor. Chlorpromazine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 117-21.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 245-46.
  3. Chlorpromazine hydrochloride. Beverley, Hull: Dr. Reddy's Laboratories (UK) Ltd.; 2005 [revised 14 Dec. 2016]. [Accessed 20 Mar. 2019] (online) Available from:
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: A N Pharmacia
Address: 315, 3rd Floor DLF Tower B, Jasola, Delhi -110044

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver CPZ 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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