Covnib 2mg Tablet is a Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis. It helps decrease pain, tenderness, and swelling in the joints by reducing inflammation. It also helps slow the progression of bone and joint damage.

Covnib 2mg Tablet can be taken with or without food, but it is best to take them at the same time each day. Your dose will depend on your condition and what other medicines you are taking. You should use it as your doctor tells you to. Do not stop taking this medicine unless your doctor tells you to because your condition could get worse.

The most common side effects of Covnib 2mg Tablet include throat and nose infections, nausea, and viral infection. You may also get cold sores, a feeling of sickness, or have symptoms of a cold like stuffy nose, sneezing, and sore throat. There are other less common side effects, some of them serious, including blood clots and tears in the stomach or intestine wall. These need urgent medical attention. If you have concerns regarding side effects, talk to your doctor.

You may need blood tests before you are given this medicine and you should not start taking it if you have any kind of infection. Make sure you talk to your doctor before starting treatment if you have or have ever had, tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Covnib 2mg Tablet can make you more likely to get infections or may worsen any current infections so avoid contact with people who have things you might catch (e.g., chickenpox, measles or flu). This medicine is not suitable for children under 18 years old and you should not use it if you’re pregnant or breastfeeding, unless your doctor feels the benefit is greater than the risk. Your doctor may need to examine you on a regular basis.

Uses of Covnib Tablet

Rheumatoid arthritis

Benefits of Covnib Tablet

In Rheumatoid arthritis

Covnib 2mg Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.

Side effects of Covnib Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Covnib

Upper respiratory tract infection
Nausea
Herpes virus infection
Cold sores
Viral infection
Sore throat

How to use Covnib Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Covnib 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Covnib Tablet works

Covnib 2mg Tablet is a Janus kinase (JAK) inhibitor that inhibits the activity of selective JAK1 and JAK2 enzymes, which interfere with the JAK-STAT signaling pathway (a chain of protein-cell interactions, involved in processes such as immunity, cell division, cell death, and tumor formation).

Safety advice

Alcohol

SAFE

Consuming alcohol with Covnib 2mg Tablet does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Covnib 2mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Covnib 2mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Covnib 2mg Tablet does not usually affect your ability to drive.

Kidney

UNSAFE

Covnib 2mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Covnib 2mg Tablet is safe to use in patients with liver disease. No dose adjustment of Covnib 2mg Tablet is recommended.
Covnib 2mg Tablet may not be recommended in patients with severe liver disease due to lack of information and research. Therefore, it is important to consult the doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Covnib 2mg Tablet

₹8.5/Tablet

Olumiant 2mg Tablet

Eli Lilly and Company India Pvt Ltd

₹960.57/tablet

11201% costlier

Quick tips

Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts or cholesterol level.
Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Fact Box

Chemical Class

Pyrrolo Pyrimidine Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Janus kinase inhibitors

Patient concerns

Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason?

Dr. Mehtab Baig

Orthopaedic Physiotherapy

This is the test for rheumatoid arthritis

What is gatheya. What is it solution

Dr. Akshat Goel

Orthopaedics

It is supposed to be Rheumatoid Arthritis

FAQs

Q. Can I take Covnib 2mg Tablet if I have liver problems?

Inform your doctor if you have liver problems, before starting Covnib 2mg Tablet. This is done because in some cases Covnib 2mg Tablet may cause an increase in liver enzymes. Therefore, your liver function needs to be investigated before starting Covnib 2mg Tablet. Although, Covnib 2mg Tablet can be given to patients with mild to moderate liver function impairment, but should not be prescribed to patients with severe liver impairment.

Q. Can Covnib 2mg Tablet cause cancer?

Covnib 2mg Tablet may increase the chances of developing the risk of certain cancers (lymphoma and other cancers including skin cancers) by affecting the working of the immune system. Hence, inform your doctor if you ever had or have any type of cancer.

Q. Do I need to get any investigations done before starting Covnib 2mg Tablet?

You may need to get your blood tests done before you start Covnib 2mg Tablet or while you are taking it. Blood tests are done in order to check if you have a low red blood cell count (anemia), low white blood cell count (neutropenia or lymphopenia), high blood fat (cholesterol) or high levels of liver enzymes. It also helps to ensure that treatment with Covnib 2mg Tablet is not causing problems. In addition to this, your doctor may advise you to get tested for tuberculosis before starting Covnib 2mg Tablet, as using Covnib 2mg Tablet may make an existing infection worse.

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

Related ayurvedic ingredients

Fish Oil

Top Rheumatologists

Dr. Naval Mendiratta

MBBS, MD, Fellowship

4.7 ★

Dr. Prasan Deep Rath

MBBS, MD, Fellowship, Certification, Fellowship

4.4 ★

4.3 ★

4.9 ★

5 ★

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Eli Lilly and Company. Olumiant (baricitinib). [Accessed 25 Jan. 2019] (online) Available from:
Drugs.com. Baricitinib. [Accessed 02 Apr. 2019] (online) Available from:
Baricitinib. Indianapolis, Indiana: Lilly USA; 2018. [Accessed 02 Apr. 2019] (online) Available from:
Baricitinib [Product Label]. Eli Lilly and Company; 2020. [Accessed 09 Jun, 2023] (online) Available from:
Medscape. Baricitinib. [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

Name: Torrent Pharmaceuticals Ltd

Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.