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Clobe 10 Tablet

Written By Dr. Mayank, Pharm.D
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 13 Oct 2025 | 04:21 PM (IST)
Clobe 10 Tablet belongs to a class of medicines known as benzodiazepines. It is used to treat epilepsy (seizures) and severe anxiety. It works by suppressing the abnormal and excessive activity of the nerve cells in the brain.
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General Information

Contains

Clobazam (10mg)

Marketer

Axonwave Pharmaceuticals Private Limited

Storage

Store below 30°C
The content is shown in English
Clobe 10 Tablet image
Clobe 10 Tablet image
Clobe 10 Tablet image

Product introduction

Clobe 10 Tablet may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming.

If you have missed a dose, take it as soon as you remember and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may increase seizure frequency.

Some common side effects of this medicine include tiredness, slurred speech, fever, cough, drooling, constipation, and difficulty in passing urine. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to consult the doctor if you notice blisters on the skin or inside your mouth. If you have been taking this medicine for a long time then regular monitoring of blood and liver functions may be required.

Uses of Clobe Tablet

Benefits of Clobe Tablet

Treatment of Severe anxiety
Clobe 10 Tablet reduces the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, and irritability. Therefore, it helps one to go about their daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping it suddenly can cause serious problems; so, do not stop taking it without discussing with the doctor.
Treatment of Epilepsy/Seizures
Clobe 10 Tablet slows down electrical signals in the brain that cause seizures (fits). It can also help reduce symptoms of seizures, such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. This medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Therefore, do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.

Side effects of Clobe Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clobe
  • Constipation
  • Dizziness
  • Dryness in mouth
  • Fatigue
  • Decreased appetite
  • Headache
  • Nausea
  • Irritability
  • Aggression
  • Restlessness
  • Drug tolerance
  • Difficulty in paying attention
  • Tremors
  • Abnormality of voluntary movements
  • Sleepiness
  • Depression
  • Sedation
  • Speech disorder

How to use Clobe Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clobe 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Clobe Tablet works

Clobe 10 Tablet is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Inform your doctor if you notice sores or blisters on your skin, lips, or inside your mouth.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Safety advice

Alcohol

Alcohol

UNSAFE
Clobe 10 Tablet may cause excessive drowsiness with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Clobe 10 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Clobe 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Short-term use is not expected to cause any adverse effects in the breastfed baby, especially if the baby is older than 2 months. During long-term use, monitor for possible sleepiness.
Driving

Driving

UNSAFE
Clobe 10 Tablet may cause side effects which could affect your ability to drive.
You may feel sleepy or have concentration or memory problems after taking Clobe 10 Tablet and this may affect your ability to drive.
Kidney

Kidney

CAUTION
Clobe 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Clobe 10 Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Clobe 10 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver

Liver

CAUTION
Clobe 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Clobe 10 Tablet may be needed. Please consult your doctor.
Limited information is available on use of Clobe 10 Tablet in patients with severe liver disease.

Interaction with drugs

Taking Clobe with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tramadol (Injection Route)

If concurrent use is essential, watch out for symptoms of Clobazam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Clobazam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Clozapine (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, headaches, tremors, sleep disturbances or mood changes and consult your doctor if you experience them. They may adjust the doses as per the observations.
Severe

Tramadol (Oral Route)

If concurrent use is essential, watch out for symptoms of Clobazam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Clobazam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Morphine (Oral Route)

If concurrent use is essential, watch out for symptoms of Clobazam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Clobazam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Codeine (Oral Route)

If concurrent use is essential, watch out for symptoms of Clobazam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Clobazam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Yes, Clobe 10 Tablet can be habit forming if used for a long time. The risk of dependence increases with dose and duration of treatment; it is also greater in patients with a history of alcohol or drug abuse. Therefore, the duration of treatment is generally as short as possible.
Yes, Clobe 10 Tablet can make you sleepy. It usually begins within the first month of treatment and may diminish with continued treatment.
Clobe 10 Tablet is a fast-acting medicine, which means that it quickly gets absorbed from the bloodstream. Clobe 10 Tablet reaches its highest blood levels within half an hour to 4 hours after the dose is taken.
No, Clobe 10 Tablet and clonazepam are not the same medicines but belong to the same class of drugs known as benzodiazepines.
Withdrawal syndrome may develop at any time up to 3 weeks after stopping Clobe 10 Tablet. Withdrawal signs may last anywhere from 4 weeks to a year or more.
No, do not stop taking Clobe 10 Tablet even if you are feeling well, unless your doctor tells you to. Suddenly stopping Clobe 10 Tablet may cause unwanted effects known as withdrawal symptoms. To prevent this, the dose of clobazam needs to be reduced gradually before completely stopping it. Therefore, it is important that you consult your doctor first.
Yes, Clobe 10 Tablet can be habit forming if used for a long time. The risk of dependence increases with dose and duration of treatment; it is also greater in patients with a history of alcohol or drug abuse. Therefore, the duration of treatment is generally as short as possible.
Yes, Clobe 10 Tablet can make you sleepy. It usually begins within the first month of treatment and may diminish with continued treatment.
Clobe 10 Tablet is a fast-acting medicine, which means that it quickly gets absorbed from the bloodstream. Clobe 10 Tablet reaches its highest blood levels within half an hour to 4 hours after the dose is taken.
No, Clobe 10 Tablet and clonazepam are not the same medicines but belong to the same class of drugs known as benzodiazepines.
Withdrawal syndrome may develop at any time up to 3 weeks after stopping Clobe 10 Tablet. Withdrawal signs may last anywhere from 4 weeks to a year or more.
No, do not stop taking Clobe 10 Tablet even if you are feeling well, unless your doctor tells you to. Suddenly stopping Clobe 10 Tablet may cause unwanted effects known as withdrawal symptoms. To prevent this, the dose of clobazam needs to be reduced gradually before completely stopping it. Therefore, it is important that you consult your doctor first.
Taking more than the recommended doses of Clobe 10 Tablet can affect in different ways, and the patient should seek immediate medical help. In mild cases, it may cause symptoms such as drowsiness, mental confusion, and tiredness. Whereas, in more serious cases, the symptoms may include the complete loss of control of bodily movements, decreased muscle tone, low blood pressure, respiratory depression, coma in rare cases, and death in very rare cases.
Clobe 10 Tablet tablets can be taken whole, broken in half along the score, or crushed and mixed in applesauce. Clobe 10 Tablet can be taken with or without food.
Generally, the use of Clobe 10 Tablet does not cause a decrease in the blood pressure, but taking more than the recommended doses of Clobe 10 Tablet may cause a fall in the blood pressure
Clobe 10 Tablet may cause tiredness along with muscle weakness. In case you experience tiredness or if tiredness persists for a long time, then you should consult your doctor.
No, Clobe 10 Tablet dose not cause depression, but it can cause recurrence of pre-existing depression.

Fact Box

Chemical Class

Benzodiazepines Derivative

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Benzodiazepines

References

  1. Porters RJ, Meldrum BS. Antiseizure Drugs. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 415.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 293-94.
  3. Clobazam. Winchester, Kentucky: Catalent Pharma Solutions, LLC; 2011 [revised Jun. 2018]. [Accessed 19 Jun. 2019] (online) Available from:
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Clobazam. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 20 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Axonwave Pharmaceuticals Private Limited
Address: Plot No.178, Kh No.117 Vipin Garden Extn. Uttam Nagar West Delhi DL 110059 India

Vendor Details

Country of origin: India

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