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Clobazam is used to treat severe anxiety over a short time, fits (epilepsy), mental illness, such as schizophrenia (in combination with other treatments) and Lennox-Gastaut Syndrome (fits in patients with 2 years of age or older). 

How it works

Clobazam belongs to class of medications called benzodiazepine. It works by decreasing abnormal electrical activity in the brain.

Common side effects

Frequent urge to urinate, Skin rash, Allergic reaction, Difficulty in speaking, Joint pain, Blisters on skin, Change in appetite, Coordination impaired, Cough, Dry mouth, Fatigue, Shortness of breath, Sore mouth, Sore throat, Urticaria, Vomiting, Constipation, Fever


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Expert advice

Clobazam may be habit forming. Keep the medication in a place where others/ children cannot get to it. Do not drive, operate heavy machinery or perform activities that require alertness while on this drug Always follow the instructions of doctor regarding the dosage and duration. Do not start or continue clobazam:
  • if you are allergic to clobazam, or to any of the other ingredients of this medicine.
  • if you are in the first three months of pregnancy or if you are breast-feeding.
  • if you have ever had problems with drugs or alcohol dependence in the past.
  • if you suffer from an illness that causes muscle weakness (called ‘myasthenia gravis’).
  • if you have liver problems or breathing problems or you stop breathing for short periods during sleep (called ‘sleep apnea syndrome’).
  • Brain disease (head injury, brain damage).
Talk with your doctor before taking clobazam:
  • if you have liver or kidney disease.
  • if you have a history of depression or suicidal thoughts or behaviour.
  • if you are over 65. 

Frequently asked questions


Q. Is clobazam/ frisium a benzodiazepine or narcotic or a controlled drug or sedative or addictive?
Clobazamis benzodiazepine and controlled drug (addictive), but not a narcotic substance and doesn’t cause addiction.
Q. Is clobazam FDA approved?
It is approved by FDA.
Q. Is clobazamthe same as Valium?
Both of this drugs belongs a to a class called benzodiazepine, but their effects are different.
Q. Is clobazam safe?
Clobazam is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Does clobazam cause weight gain/ make you sleepy or tired?
Clobazam may cause weight gain,make you feel sleepy or dizzy, especially when you first start treatment. Contact your doctor if you develop such symptom.
Q. Does clobazam get you high?
Yes. But do not use this medicine without prescription as this medicine has potential for abuse with many side effects.

Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)