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Brethnol Syrup

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Brethnol Syrup is used to relieve symptoms of asthma and chronic obstructive pulmonary diseases (COPD) such as coughing, wheezing, and breathlessness. It helps in relaxing the muscles of the air passages, thus widening it and making it easier to breathe.
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The content is shown in English
Brethnol Syrup image
Brethnol Syrup image

Product introduction

You can take Brethnol Syrup with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. Use this medicine regularly to get the most benefit from it even if you feel well.

This medicine is generally safe however it may cause tremors, headaches, palpitation, fast heart rate, nervousness, and muscle cramps in some people. These are often not dangerous and should gradually improve as your body gets used to the medicine. There are other, rarer, side effects and you should call your doctor straight away if you get chest pain, a very bad headache, or very bad dizziness.

Before using this medicine, you should tell your doctor if you have high blood pressure, an overactive thyroid gland, a history of heart problems, diabetes, or low levels of potassium in your blood to make sure it is safe. Also, make sure your doctor knows if you are pregnant or breastfeeding before taking this medicine. This medicine can make you feel dizzy or shaky so avoid driving, cycling, or using tools or machinery until you feel better. You should not smoke as it causes damage to your lungs and will make your condition worse.

Benefits of Brethnol Syrup

Asthma
Brethnol Syrup can help prevent the onset of an asthma attack if it is taken before exercise or exposure to some “triggers”. These may include house dust, pollen, pets and cigarette smoke. This medicine will allow you to exercise more freely without worrying about getting symptoms such as wheezing, coughing and shortness of breath. It allows you to live your life more freely without worrying so much about things that set off your symptoms.
Chronic obstructive pulmonary disease (COPD)
Bronchodilators like Brethnol Syrup help the airways in your lungs stay open. They work by relaxing the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.

Side effects of Brethnol Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Brethnol
  • Tremors
  • Headache
  • Palpitations
  • Increased heart rate
  • Muscle cramp
  • Nervousness

How to use Brethnol Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Brethnol Syrup may be taken with or without food.

How Brethnol Syrup works

Brethnol Syrup is a bronchodilator. It works by relaxing the muscles in the airways and widens airways. This makes breathing easier.

Quick tips

  • Brethnol Syrup is used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD) such as coughing, wheezing and breathlessness.
  • It must be taken regularly to help keep the airways open at all times.
  • Your doctor may regularly monitor your blood potassium levels. Inform your doctor if you notice muscle twitching, weakness, or an irregular heartbeat.
  • Inform your doctor if you have a history of heart diseases or if you experience headaches, or chest pain.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Brethnol Syrup. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Brethnol Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

UNSAFE
Brethnol Syrup may cause side effects that could affect your ability to drive.
Brethnol Syrup may cause side effects such as dizziness, increased or uneven heart rate, muscle cramps or muscle pain. This may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Brethnol Syrup in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Brethnol Syrup in patients with liver disease.

Interaction with drugs

Taking Brethnol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Propranolol (Oral Route)

Do not use Propranolol with Salbutamol if you have asthma or COPD. Propranolol may reduce efficacy of Salbutamol.
Severe

Timolol (Eye Route)

Do not use Timolol with Salbutamol if you have asthma or COPD. Timolol may reduce efficacy of Salbutamol.
Severe

Pindolol (Oral Route)

Do not use Pindolol with Salbutamol if you have asthma or COPD. Pindolol may reduce efficacy of Salbutamol.
Severe

Propranolol (Injection Route)

Do not use Propranolol with Salbutamol if you have asthma or COPD. Propranolol may reduce efficacy of Salbutamol.
Severe

Levobunolol (Eye Route)

Do not use Levobunolol with Salbutamol if you have asthma or COPD. Levobunolol may reduce efficacy of Salbutamol.

Frequently asked questions

Yes, Brethnol Syrup is considered safe, but its use depends on the severity of your heart problem. If you experience chest pain or any other symptom of worsening heart disease while taking Brethnol Syrup, seek immediate medical advice.
Brethnol Syrup may cause blood sugar levels to rise. Therefore, your doctor may adjust your dose of insulin or antidiabetic medicines. Keep a regular check on your blood glucose levels and do not miss any appointments. Consult your doctor if you experience a sudden rise in blood sugar levels.
Yes, it could be due to Brethnol Syrup. Feeling shaky is a common side effect of Brethnol Syrup which goes away after some time. For headaches, drink plenty of water, get sufficient rest and avoid alcohol. Usually headaches go away after a week. If they persist for a long time, contact your doctor.
Use Brethnol Syrup as and when you need it. Brethnol Syrup relieves the symptoms of asthma like coughing, shortness of breath and tightness in the chest. You can also take it to prevent asthma attacks in circumstances where you know it may occur (e.g., after strenuous exercise or unavoidable exposure to allergen).
No, you should not smoke while taking Brethnol Syrup. Smoking irritates the lungs. The medicine may make breathing more difficult, especially in patients who have asthma. Take advice from your doctor if you are finding it hard to avoid smoking.

Fact Box

Chemical Class

Benzyl alcohols

Habit Forming

No

Therapeutic Class

RESPIRATORY

Action Class

Short-Acting β2-Agonists (SABA)

References

  1. Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 291.
  2. Boushey HA. Drugs Used in Asthma. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 344.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 30-32.
  4. Salbutamol. Stockley Park West Uxbridge: Glaxo Wellcome UK Ltd.; 2005 [revised 5 Feb. 2015]. [Accessed 01 Apr. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 01 Apr. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
  7. NAFDA. Salbutamol [Product Label]. [Accessed 06 Aug. 2023] (online) Available from:
  8. Albuterol [Prescribing Information]. Bridgewater, NJ: Amneal Pharmaceuticals LLC; 2023. [Accessed 06 Aug. 2023] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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