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Bisotidine 400mg Tablet

Prescription Required

Product introduction

Bisotidine 400mg Tablet is an antacid. It reduces the amount of acid produced by your stomach. It is used to treat and prevent heartburn, indigestion and other symptoms caused by too much acid in the stomach. It is also used to treat and prevent stomach ulcers, reflux disease and some other rare conditions.

Bisotidine 400mg Tablet is also commonly prescribed to prevent stomach ulcers and heartburn caused due to the use of painkillers. It must be swallowed whole with water preferably before meals to prevent the symptoms of acidity. The medicine must be taken in dose and duration as advised by the doctor. This medicine should relieve indigestion and heartburn within a few hours. If the symptoms persist or get worse even after 14 days of treatment, you should consult your doctor immediately. It is not recommended to take this medicine in severe stomach disease. You can help the medicine work better by eating smaller meals more often and avoiding spicy or oily foods.

Most people who take it do not have any side effects but the most common ones include headache, dizziness, diarrhea, muscle pain, skin rash, and tiredness. If you do get a side effect, it is usually mild and will go away when you stop taking this medicine or as you adjust to it. Consult your doctor if any of these side effects bother you or do not go away.

Before taking it, you should tell your doctor if you have any heart, kidney, or liver diseases so that your doctor can prescribe a suitable dose for you. Also, tell your doctor if you are taking other medications. This medicine is usually considered safe to take during pregnancy and breastfeeding if it has been prescribed by a doctor. Avoid drinking alcohol as this can increase the amount of acid in your stomach and make your symptoms worse.

Uses of Bisotidine Tablet

Benefits of Bisotidine Tablet

In Heartburn

Heartburn is a burning feeling in your chest caused by stomach acids travelling back up towards your throat and mouth (acid reflux). It happens because a muscle above your stomach relaxes too much and allows stomach contents and acid to come back up into your esophagus and mouth. This can be a symptom of indigestion (dyspepsia). Bisotidine 400mg Tablet works by reducing the amount of acid your stomach makes and relieves the pain associated with heartburn and indigestion.You should take it exactly as it is prescribed by your doctor for it to be effective. Some simple lifestyle changes can help stop or reduce heartburn. Think about what foods trigger heartburn and try to avoid them; eat smaller more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3–4 hours of going to bed.

Side effects of Bisotidine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bisotidine

  • Headache
  • Dizziness
  • Diarrhea
  • Muscle pain
  • Skin rash
  • Tiredness

How to use Bisotidine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bisotidine 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Bisotidine Tablet works

Bisotidine 400mg Tablet is a histamine H2 receptor antagonist. It works by reducing the amount of acid produced in the stomach which helps relieve acid-related indigestion and heartburn.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Bisotidine 400mg Tablet.
Pregnancy
SAFE IF PRESCRIBED
Bisotidine 400mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Bisotidine 400mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
SAFE
Bisotidine 400mg Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Bisotidine 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Bisotidine 400mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Bisotidine 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bisotidine 400mg Tablet may be needed. Please consult your doctor.

What if you forget to take Bisotidine Tablet?

If you miss a dose of Bisotidine 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Bisotidine 400mg Tablet
₹3.15/Tablet
C Met 400mg Tablet
Cyper Drugs & Pharmaceuticals Pvt Ltd
₹1.36/tablet
57% cheaper
Neotid 400mg Tablet
Neon Laboratories Ltd
₹2.48/tablet
21% cheaper
₹1.36/tablet
57% cheaper
Cimetiget 400mg Tablet
Franco-Indian Pharmaceuticals Pvt Ltd
₹1.44/tablet
54% cheaper
Ulciban 400mg Tablet
Torrent Pharmaceuticals Ltd
₹2.48/tablet
21% cheaper

Quick tips

  • Take Bisotidine 400mg Tablet before going to bed if you are taking this medicine once a day. It is very effective in controlling stomach acid that is released when you are asleep.
  • Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
  • Inform your doctor if you do not feel better after taking Bisotidine 400mg Tablet for 2 weeks as you may be suffering from some other problems.
  • Inform your doctor if you have ever been diagnosed with kidney disease as dose of your medicine may need to be adjusted.
  • Inform your doctor about any other medications or supplements that you are taking because Bisotidine 400mg Tablet can interfere with the working of other medications.
  • Do not stop taking the medication without talking to your doctor. 
  • Bisotidine 400mg Tablet is a well tolerated and safe medicine with a very low incidence of side effects.
  • Take it with or without food.
  • Take Bisotidine 400mg Tablet before going to bed if you are taking this medicine once a day. It is very effective in controlling stomach acid that is released when you are asleep.
  • If you are also taking other medications to treat acidity (e.g., antacid), take them 2 hours before or after taking Bisotidine 400mg Tablet.
  • Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
  • Inform your doctor if you do not feel better after taking Bisotidine 400mg Tablet for 2 weeks as you may be suffering from some other problems.
  • Inform your doctor if you have ever been diagnosed with kidney disease as dose of your medicine may need to be adjusted.
  • Do not stop taking the medication without talking to your doctor. 

Fact Box

Chemical Class
Imidazoles Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Histamine Type-2 Receptor Antagonists (H2 Blockers)

Interaction with drugs

Taking Bisotidine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Cimetidine may reduce blood levels of Dasatinib. Do not consume Dasatinib with Cimetidine.
Cimetidine may raise blood levels of the active form of Fosphenytoin. Concurrent use may decrease ability of bone marrow to produce blood cells. Do not consume Fosphenytoin with C... More
Concurrent use may decrease the ability of bone marrow to produce blood cells. Do not consume Phenytoin with Cimetidine.
Concurrent use may cause decreased blood cell production. If concurrent use is essential, your doctor may monitor blood cell counts and your overall treatment closely.
Concurrent use may decrease the ability of bone marrow to produce blood cells. Do not consume Phenytoin with Cimetidine.

Patient concerns

arrow
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
Having problem of acid reflux disease with throat infection and pain in right side of abdomen
Dr. Aanchal Maheshwari
Ayurveda
take avipattikar churan 1 spoon twice before meal, for throat infection do gargles with lyuke warm water and mixing tankan bhasma a littlein it,,
arrow

FAQs

How can Bisotidine 400mg Tablet cause gynecomastia?

Bisotidine 400mg Tablet causes gynecomastia (enlarged breasts of males) by decreasing the male hormone (testosterone) levels and blocking the sensitivity of the target areas on which testosterone acts. However, the breast enlargement is not bothersome. Please consult your doctor if this worries you.

Can I take Bisotidine 400mg Tablet with loperamide?

Bisotidine 400mg Tablet can decrease the metabolism of Loperamide, increase its blood levels. This can in turn increase the effects and side effects of Loperamide. So, consult your doctor prior to taking both the medicines together as your dose of Loperamide may need to be decreased.

Is there any vitamin and mineral loss when Bisotidine 400mg Tablet is taken?

Bisotidine 400mg Tablet is not known to cause vitamin and mineral loss or deficiency. However, Bisotidine 400mg Tablet belongs to the class of H2 receptor blocker which can decrease vitamin B12 absorption and cause its deficiency as reported in some studies especially when used for more than two years.

Is Bisotidine 400mg Tablet an antacid?

No, Bisotidine 400mg Tablet is not an antacid as it does not neutralize the acids of the stomach rather it works by decreasing the production of the acid.

Are there any withdrawal symptoms associated with the use of Bisotidine 400mg Tablet?

Clinical studies or reports so far have not reported any withdrawal symptoms when the patient stops taking Bisotidine 400mg Tablet and this suggests that Bisotidine 400mg Tablet has no addictive potential.

Can I take Bisotidine 400mg Tablet with antacids?

Antacids and Bisotidine 400mg Tablet both can be taken at the same time as they are not known to affect each other’s action. However, both Bisotidine 400mg Tablet and antacids help in decreasing the acidity and use of more than one drug for the same effect is not advisable unless absolutely necessary.

Can I take Bisotidine 400mg Tablet with coffee?

There are no reports of any harmful effects of taking Bisotidine 400mg Tablet along with coffee. However, Bisotidine 400mg Tablet can decrease the breakdown of coffee and increase its effects. Also, coffee is a gastric stimulant and can increase acid secretion and aggravate your underlying condition.

How is Omeprazole better than Bisotidine 400mg Tablet?

Omeprazole is a proton pump inhibitor and Bisotidine 400mg Tablet is an H2 receptor blocker. They act in different ways but both decrease the acid production in the stomach. However, according to some studies, omeprazole is more potent, longer acting, and has fewer side effects when compared to Bisotidine 400mg Tablet.

Why should Bisotidine 400mg Tablet be taken at bedtime?

Bisotidine 400mg Tablet can be given as a single daily dose or as multiple daily doses depending on your condition. When given in a single dose, it is preferred that you should take it before going to bed as it is very effective in decreasing nighttime acid secretion and a fixed time will help you to remember to take the medicine.

Does Bisotidine 400mg Tablet work for molluscum contagiosum?

Oral Bisotidine 400mg Tablet has been seen to be effective in treating molluscum in children. However, this is not an approved indication for its use. Please consult your doctor before taking it for this condition.

Why does Bisotidine 400mg Tablet increase the action of opiates?

Bisotidine 400mg Tablet increases the action of an opioid like substances by inhibiting enzymes which are responsible for the breakdown of opiates. Due to a decrease in the breakdown, opioid levels increase in the body and hence their action is also increased.

Is Bisotidine 400mg Tablet available over the counter?

No, Bisotidine 400mg Tablet is not available as an over-the-counter medication. It is a prescription medicine and is available only when prescribed by a physician.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, BC Knollmann, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 29 Jan. 2019] (online) Available from:External Link
  2. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Cimetidine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Globela Pharma Pvt Ltd
Address: 357, G.I.D.C. Road No.3,Sachin, Surat - 394 230 ,Gujarat, India
Country of origin: India

31.5
Inclusive of all taxes
MRP32.5  3% OFF
10.0 tablets in 1 strip
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