Bigatra 75mg Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 02 Mar 2026 | 11:50 PM (IST)

Bigatra 75mg Tablet is a medicine that helps prevent and treat blood clots. It is used for the treatment and prevention of deep vein thrombosis (DVT), treatment and prevention of pulmonary embolism (PE), and to reduce the risk of stroke in people with certain heart rhythm problems such as atrial fibrillation.

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General Information

Contains

Dabigatran Etexilate (75mg)

Marketer

Aprica Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Bigatra 75mg Tablet should be taken exactly as prescribed by your doctor, usually at regular intervals each day to maintain a steady blood-thinning effect. Taking the medicine with food may help reduce stomach discomfort. Do not skip doses, because missing doses or stopping treatment early can increase the risk of clot formation or stroke. Regular follow-up visits and kidney function checks may be required to ensure the medicine is working safely and effectively.

The most common side effects of Bigatra 75mg Tablet are related to bleeding and stomach-related problems such as indigestion, abdominal discomfort, nausea, or stomach irritation. Mild bruising or minor bleeding, such as nosebleeds or bleeding gums, may occur because the medicine reduces the blood’s ability to clot. Contact your doctor if bleeding lasts longer than usual, becomes severe, or if you notice unusual symptoms such as black stools, blood in urine, or dizziness.

Bigatra 75mg Tablet can increase the risk of serious or sometimes life-threatening bleeding, so extra caution is needed during treatment. Do not stop taking this medicine without medical advice, as sudden discontinuation can increase the risk of stroke or clot formation. Inform your doctor before any surgery, dental procedure, or spinal injection, since the medicine may need to be temporarily stopped to reduce bleeding risk.

This medicine should not be used in people with active bleeding, severe allergy to the medicine, or mechanical heart valves. Certain medicines, especially other blood thinners, pain relievers such as NSAIDs, or drugs that affect P-glycoprotein, may increase bleeding risk and should only be taken after medical consultation. Patients with kidney problems or older adults may require closer monitoring because the drug stays longer in the body. Pregnant and breastfeeding women should consult their doctors before taking this medicine to make sure it is safe for them.

Uses of Bigatra Tablet

Benefits of Bigatra Tablet

Treatment and prevention of Deep vein thrombosis
Bigatra 75mg Tablet helps treat and prevent deep vein thrombosis, a condition in which blood clots form in the deep veins, usually in the legs. It works by preventing the clot from growing larger and reducing the chance of new clots forming. This helps improve blood flow, relieves symptoms such as pain and swelling, and lowers the risk of serious complications caused by clot movement.

Treatment and prevention of Pulmonary embolism
In pulmonary embolism, a blood clot travels to the lungs and blocks blood flow, which can be life-threatening if untreated. This medicine helps stop existing clots from getting bigger and reduces the risk of new clots forming. Keeping the blood flowing more smoothly supports recovery, improves breathing symptoms, and helps prevent recurrence of pulmonary embolism.

Prevention of Stroke
Bigatra 75mg Tablet helps reduce the risk of stroke caused by blood clots, especially in people with certain heart rhythm disorders such as atrial fibrillation. It prevents harmful clots from forming and traveling to the brain, where they could block the blood supply. When used regularly as prescribed, it helps protect brain function and lowers the risk of long-term disability associated with stroke.

Side effects of Bigatra Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bigatra

Nausea
Anemia (low number of red blood cells)
Gastrointestinal bleeding
Diarrhea
Abdominal pain
Increased bleeding tendency

How to use Bigatra Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bigatra 75mg Tablet may be taken with or without food.

How Bigatra Tablet works

Bigatra 75mg Tablet works by slowing down the blood clotting process. It blocks the action of thrombin, a substance in the blood that helps form clots. Reducing clot formation helps prevent new clots from developing and stops existing clots from getting bigger, lowering the risk of stroke and other clot-related problems such as deep vein thrombosis and pulmonary embolism.

Quick tips

Bigatra 75mg Tablet increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects, or engaging in contact sports (e.g., football and wrestling).
If you are going to have surgery or dental treatment, you may be asked to stop taking Bigatra 75mg Tablet temporarily.
Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not stop taking the medication without talking to your doctor.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bigatra 75mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Bigatra 75mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Bigatra 75mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Bigatra 75mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Bigatra 75mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Bigatra 75mg Tablet is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Bigatra 75mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Bigatra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Amiodarone (Oral Route)

Watch out for symptoms of anemia or bleeding, and consult your doctor if you experience them. Your doctor may discontinue Dabigatran Etexilate if severe bleeding occurs. Amiodarone may raise blood levels of Dabigatran Etexilate.

Severe

Amiodarone (Injection Route)

Severe

Carbamazepine (Oral Route)

Do not consume Dabigatran Etexilate with Carbamazepine. Carbamazepine may reduce blood levels of Dabigatran Etexilate.

Severe

Fluconazole (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may discontinue Dabigatran Etexilate accordingly. Fluconazole may raise blood levels of Dabigatran Etexilate.

Severe

Fluconazole (Injection Route)

Frequently asked questions

When should I take Bigatra 75mg Tablet?

Mostly, Bigatra 75mg Tablet is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours.

Can I drink alcohol with Bigatra 75mg Tablet?

Taking alcohol while taking Bigatra 75mg Tablet can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.

Can Bigatra 75mg Tablet cause hair loss?

As compared to other blood-thinning medications, Bigatra 75mg Tablet does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Bigatra 75mg Tablet. Consult your doctor if you face hair loss while taking Bigatra 75mg Tablet to rule out any other causes of hair loss.

When will I feel better after taking Bigatra 75mg Tablet?

Bigatra 75mg Tablet reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Bigatra 75mg Tablet. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Does Bigatra 75mg Tablet affect the liver?

Unlike other anticoagulants, Bigatra 75mg Tablet usually does not affect the functioning of the liver. But long-term use of Bigatra 75mg Tablet may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.

How should I store Bigatra 75mg Tablet?

Bigatra 75mg Tablet should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Store the medicine at a dry place and protect the capsules from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once the bottle is opened, it should be used within 4 months. If unused within 4 months, please discard them safely.

Can the use of Bigatra 75mg Tablet increase the risk of bleeding?

Yes, Bigatra 75mg Tablet increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Who should not take Bigatra 75mg Tablet?

People experiencing any unusual bleeding or people allergic to Bigatra 75mg Tablet should not take it. Bigatra 75mg Tablet should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced.

Fact Box

Chemical Class

Benzimidazoles

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Oral Direct Thrombin Inhibitors

Related lab tests

Activated Partial Thromboplastin Time

Complete Blood Count

Platelet Count

Prothrombin Time

References

Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-66.
Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 594.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelet Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 363-65.
Dabigatran etexilate [Summary of Product Characteristics]. 2025. [Accessed 03 Mar. 2026] (online) Available from:
Dabigatran etexilate mesylate [Prescribing Information]. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2023. [Accessed 15 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Dabigatran Etexilate. [Accessed 15 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aprica Pharmaceuticals Pvt Ltd
Address: A/4 4th Floor, Safal Profitaire,Corporate Road,Nr Prahladnagar Garden, Prahladnagar,Ahmedabad- 380015, Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Bigatra 75mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Bigatra 75mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Bigatra Tablet

Benefits of Bigatra Tablet

Side effects of Bigatra Tablet

How to use Bigatra Tablet

How Bigatra Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Amiodarone (Oral Route)

Amiodarone (Injection Route)

Carbamazepine (Oral Route)

Fluconazole (Oral Route)

Fluconazole (Injection Route)

Frequently asked questions

When should I take Bigatra 75mg Tablet?

Can I drink alcohol with Bigatra 75mg Tablet?

Can Bigatra 75mg Tablet cause hair loss?

When will I feel better after taking Bigatra 75mg Tablet?

Does Bigatra 75mg Tablet affect the liver?

How should I store Bigatra 75mg Tablet?

Can the use of Bigatra 75mg Tablet increase the risk of bleeding?

Who should not take Bigatra 75mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Activated Partial Thromboplastin Time

Complete Blood Count

Platelet Count

Prothrombin Time

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests