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Bigatra 150mg Tablet

Prescription Required

Overview

Introduction

Bigatra 150mg Tablet is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain and heart.

Bigatra 150mg Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise and losing weight if you need to.

The most common side effect of Bigatra 150mg Tablet are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headache, seizures, allergic reactions, changes to your eyesight, and tiredness.

Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, regular blood test (PT-INR) is not required while taking this medicine.

Uses of Bigatra Tablet

Side effects of Bigatra Tablet

Common
  • Bleeding
  • Nausea
  • Stomach pain
  • Indigestion

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Bleeding
    Hold a gauze over the area that is bleeding and apply pressure. Holding an ice pack to bruises may make them fade more quickly. Seek emergency help if you are bleeding profusely or if the bleeding doesn’t stop within 15 minutes. If you are bleeding more easily than normal, try to be careful when doing activities that might cause an injury or a cut, as it may take longer to stop bleeding. Use a soft toothbrush and waxed dental floss to clean your teeth. See a doctor if you're worried about any bleeding.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Stomach pain
    Try to get plenty of rest and relax. Putting a heat pad or covered hot water bottle on your stomach may relieve the stomach pain. It may help if you eat and drink slowly and have smaller and more frequent meals. Reduce your intake of coffee, tea and alcohol as these can make the pain worse. If you are in a lot of pain, speak to your doctor about possible medication. Your doctor may be able to prescribe some over-the-counter medicines to help reduce the pain.
  • Coping with Indigestion
    Try taking your medicine with a meal or snack, or shortly after eating. It might help to eat smaller and more frequent meals, and to eat and drink slowly. Avoid foods which can irritate your stomach such as carbonated soft drinks, caffeine, fatty and spicy foods, mints and citrus fruits. Quit smoking and alcohol because they increase the symptoms. Do not eat for 3 or 4 hours before going to bed. Try raising the head of your bed at night or use extra pillows. Ask your doctor or pharmacist about medicines that may help, such as antacids, if your condition does not improve.

How to use Bigatra Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bigatra 150mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Bigatra Tablet works

Bigatra 150mg Tablet is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Bigatra 150mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Bigatra 150mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Bigatra 150mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Bigatra 150mg Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Bigatra 150mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Bigatra 150mg Tablet may be needed. Please consult your doctor.
Use of Bigatra 150mg Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Bigatra 150mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bigatra 150mg Tablet may be needed. Please consult your doctor.

What if you forget to take Bigatra Tablet?

If you miss a dose of Bigatra 150mg Tablet, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Take it as per dose and duration suggested by your doctor. 
  • Bigatra 150mg Tablet increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling).
  • If you are going to have a surgery or dental treatment, you may be asked to stop taking Bigatra 150mg Tablet temporarily.
  • Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 
  • Do not stop taking the medication without talking to your doctor. 

Patient Concerns

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Deep vein thrombosis , swelling nd painful in both leg.
Dr. Sunil Sekhri
Diabetology
You need to take a surgical consultation
Looking for a specialist in Deep vein thrombosis preferably in Kochi
Dr. Nabajit Talukdar
Cardiology
See a vascular surgeon
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Do you have any questions related to Bigatra 150mg Tablet ?

FAQs

Q. When should I take Bigatra?

Mostly, Bigatra is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours. If you miss a dose of Bigatra then take it as soon as possible up to 6 hours prior to the next scheduled dose. However, skip the missed dose if your next dose is less than 6 hours away. Never take two doses of Bigatra at the same time.

Q. Can I drink alcohol with Bigatra?

Taking alcohol while taking Bigatra can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.

Q. Can Bigatra cause hair loss?

As compared to other blood-thinning medications, Bigatra does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Bigatra. Consult your doctor if you face hair loss while taking Bigatra to rule out any other causes of hair loss.

Q. When will I feel better after taking Bigatra?

Bigatra reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Bigatra. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Q. Does Bigatra affect the liver?

Unlike other anticoagulants, Bigatra usually does not affect the functioning of the liver. But long-term use of Bigatra may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.

Q. How should I store Bigatra?

Bigatra should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Store the medicine at a dry place and protect the capsules from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once the bottle is opened, it should be used within 4 months. If unused within 4 months, please discard them safely.

Q. Can the use of Bigatra increase the risk of bleeding?

Yes, Bigatra increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Q. Who should not take Bigatra?

People experiencing any unusual bleeding or people allergic to Bigatra should not take it. Bigatra should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced. The use of this medicine is not recommended in patients with severe kidney disease.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-66.
  2. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 594.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
  4. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 363-65.
  5. Dabigatran etexilate mesylate. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2010 [revised Nov. 2015]. [Accessed 15 Mar. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dabigatran. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). Dabigatran Etexilate. [Accessed 15 Mar. 2019] (online) Available from:External Link
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